Development Level

Tbio 51 | 10,625
Tchem 6 | 1,890
Tclin 1 | 602
Tdark 1 | 7,003

IMPC Term

preweaning lethality, incomple... 2 | 260
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal femur morphology 1 | 14
abnormal humerus morphology 1 | 11
abnormal tail morphology 1 | 17
decreased circulating alanine ... 1 | 53
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
enlarged heart 1 | 111
herniated abdominal wall 1 | 4
hydrometra 1 | 13
increased heart weight 1 | 37
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
preweaning lethality, complete... 1 | 633
shortened QT interval 1 | 4
small superior vagus ganglion 1 | 20

Disease

glioblastoma 30 | 5,572
ovarian cancer 30 | 8,492
osteosarcoma 28 | 7,933
psoriasis 28 | 6,685
Cancer 27 | 2,346
medulloblastoma, large-cell 27 | 6,234
lung cancer 22 | 4,473
pilocytic astrocytoma 20 | 3,086
pancreatic cancer 19 | 2,300
Breast cancer 18 | 3,099
lung adenocarcinoma 18 | 2,714
atypical teratoid / rhabdoid tumor 16 | 4,369
interstitial cystitis 16 | 2,299
invasive ductal carcinoma 16 | 2,950
non-small cell lung cancer 16 | 2,798
pediatric high grade glioma 16 | 2,712
ductal carcinoma in situ 15 | 1,745
oligodendroglioma 15 | 2,849
pituitary cancer 15 | 1,972
ulcerative colitis 15 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
posterior fossa group A ependymoma 13 | 1,511
primitive neuroectodermal tumor 13 | 3,031
cystic fibrosis 12 | 1,670
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
malignant mesothelioma 12 | 3,163
breast carcinoma 11 | 1,614
colon cancer 11 | 1,475
gastric carcinoma 11 | 832
adult high grade glioma 10 | 2,148
ependymoma 10 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
primary pancreatic ductal adenocarcinoma 10 | 1,271
subependymal giant cell astrocytoma 10 | 2,287
Carcinoma 9 | 2,147
Cleft palate 9 | 125
Duchenne muscular dystrophy 9 | 602
Obesity 9 | 616
astrocytic glioma 9 | 2,241
juvenile dermatomyositis 9 | 1,189
lung carcinoma 9 | 2,844
acute quadriplegic myopathy 8 | 1,157
astrocytoma 8 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
group 4 medulloblastoma 8 | 1,875
nasopharyngeal carcinoma 8 | 1,056
sonic hedgehog group medulloblastoma 8 | 1,482
Craniofacial Abnormalities 7 | 147
Kidney disease 7 | 397
Osteoarthritis 7 | 96
Pick disease 7 | 1,893
Prostatic Neoplasms 7 | 471
diabetes mellitus 7 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
tuberculosis 7 | 1,563
Endometriosis 6 | 535
Neoplasm Invasiveness 6 | 127
Polydactyly 6 | 93
active Crohn's disease 6 | 918
Arthritis 5 | 248
Asthma 5 | 349
Esophageal atresia 5 | 25
Osteoporosis 5 | 259
cutaneous lupus erythematosus 5 | 1,056
esophageal adenocarcinoma 5 | 737
group 3 medulloblastoma 5 | 2,254
medulloblastoma 5 | 1,524
posterior fossa group B ependymoma 5 | 1,530
primary Sjogren syndrome 5 | 789
Amyotrophic Lateral Sclerosis 4 | 432
Anemia 4 | 252
Brachydactyly 4 | 52
Cleft Lip 4 | 91
Degenerative disc disease 4 | 28
Fibrodysplasia ossificans progressiva 4 | 17
Heart disease 4 | 279
Hypospadias 4 | 65
Intellectual disability 4 | 573
Lung disease 4 | 136
Mammary Neoplasms 4 | 410
Myopia 4 | 99
Pulmonary hypertension 4 | 52
Rheumatoid Arthritis 4 | 1,171
Stomach Neoplasms 4 | 282
VACTERL association 4 | 23
Vascular disease 4 | 281
Waldenstrons macroglobulinemia 4 | 765
X-linked cerebral adrenoleukodystrophy 4 | 115
active ulcerative colitis 4 | 477
adrenocortical carcinoma 4 | 1,427
atypical teratoid/rhabdoid tumor 4 | 1,095
ovarian neoplasm 4 | 97
spina bifida 4 | 1,064
Atopic dermatitis 3 | 944
Down syndrome 3 | 548
Schizophrenia 3 | 503
aldosterone-producing adenoma 3 | 664
chronic lymphosyte leukemia 3 | 232
mucosa-associated lymphoid tissue lymphoma 3 | 480
nephrosclerosis 3 | 329

Tissue

Digestive Tract 58 | 18,473
Endocrine System 58 | 18,512
Female tissues 58 | 18,647
Liver and Pancreas 58 | 18,136
Nervous System 58 | 18,561
Urinary Tract 58 | 18,444
Blood and immune system 57 | 17,995
Cardiovascular System 57 | 17,958
Male tissues 57 | 17,969
Skin and soft tissues 56 | 18,115
Respiratory system 55 | 17,484

Target Family

Non-IDG 28 | 11,969
Transcription Factor 19 | 1,400
Enzyme 10 | 4,146
Kinase 1 | 634
Nuclear Receptor 1 | 48

GO Process

cartilage development 59 | 59
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mothers against decapentaplegic homolog 5 SMAD5 Tbio Transcription Factor -2.13357 104.4 325
Hyaluronidase-1 HYAL1 Tbio Enzyme -1.85417 78.6 191
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.80852 630.1 57
Collagen alpha-1(II) chain COL2A1 Tbio Non-IDG -2.86562 689.3 377
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.62805 3186.8 1232
Integrin beta-8 ITGB8 Tbio Non-IDG -1.38851 21.7 68
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.54189 32.3 215
Growth/differentiation factor 2 GDF2 Tchem Non-IDG -2.10341 139.5 200
Metalloproteinase inhibitor 1 TIMP1 Tbio Enzyme -3.55219 3513.4 673
Hyaluronidase-2 HYAL2 Tbio Enzyme -2.00177 102.5 193