Development Level

Tbio 53 | 11,651
Tchem 4 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
abnormal embryo size 2 | 220
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal femur morphology 1 | 14
abnormal humerus morphology 1 | 11
abnormal placenta size 1 | 20
abnormal tail morphology 1 | 25
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
long tibia 1 | 25
pallor 1 | 34
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened QT interval 1 | 4
small superior vagus ganglion 1 | 74
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 46 | 11,493
ovarian cancer 31 | 8,520
glioblastoma 30 | 5,792
Cancer 29 | 2,499
osteosarcoma 28 | 7,950
psoriasis 28 | 6,694
medulloblastoma, large-cell 27 | 6,241
lung cancer 23 | 4,740
Breast cancer 22 | 3,578
ependymoma 21 | 4,679
Astrocytoma, Pilocytic 20 | 3,081
adult high grade glioma 20 | 3,801
atypical teratoid / rhabdoid tumor 19 | 5,112
pancreatic cancer 19 | 2,398
lung adenocarcinoma 18 | 2,716
interstitial cystitis 16 | 2,312
invasive ductal carcinoma 16 | 2,951
non-small cell lung cancer 16 | 2,890
ductal carcinoma in situ 15 | 1,745
oligodendroglioma 15 | 2,850
pituitary cancer 15 | 1,972
astrocytic glioma 14 | 2,597
ulcerative colitis 14 | 1,819
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
primitive neuroectodermal tumor 13 | 3,035
cystic fibrosis 12 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
malignant mesothelioma 12 | 3,232
Autosomal recessive predisposition 11 | 1,442
Short stature 11 | 531
breast carcinoma 11 | 1,638
colon cancer 11 | 1,478
gastric carcinoma 11 | 807
Brachydactyly 10 | 156
Kidney cancer 10 | 2,613
Obesity 10 | 678
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
subependymal giant cell astrocytoma 10 | 2,287
tuberculosis 10 | 2,010
Cleft Palate 9 | 271
Duchenne muscular dystrophy 9 | 601
Hypoplastic mandible condyle 9 | 275
Mandibular hypoplasia 9 | 275
Micrognathism 9 | 275
Osteoarthritis 9 | 184
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
juvenile dermatomyositis 9 | 1,187
lung carcinoma 9 | 2,843
primary pancreatic ductal adenocarcinoma 9 | 1,109
acute quadriplegic myopathy 8 | 1,158
diabetes mellitus 8 | 1,728
nasopharyngeal carcinoma 8 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Asthma 7 | 385
Craniofacial Abnormalities 7 | 151
Kidney disease 7 | 430
Pick disease 7 | 1,894
Prostatic Neoplasms 7 | 495
group 4 medulloblastoma 7 | 1,855
Arthritis 6 | 290
Cleft Lip 6 | 141
Congenital hypoplasia of penis 6 | 176
Dull intelligence 6 | 645
Endometriosis 6 | 540
Intellectual disability 6 | 1,016
Liver Cirrhosis, Experimental 6 | 769
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Narrow thorax 6 | 53
Neoplasm Invasiveness 6 | 161
Osteoporosis 6 | 363
Poor school performance 6 | 645
Schizophrenia 6 | 1,160
active Crohn's disease 6 | 922
active ulcerative colitis 6 | 764
pediatric high grade glioma 6 | 1,064
Cognitive delay 5 | 608
Congenital clubfoot 5 | 109
Cryptorchidism 5 | 296
Disease Models, Animal 5 | 155
Global developmental delay 5 | 608
Hypertension 5 | 396
Hypertensive disease 5 | 292
Major Depressive Disorder 5 | 301
Mental and motor retardation 5 | 608
Microstomia 5 | 78
Pectus excavatum 5 | 100
Polydactyly 5 | 107
Short distal phalanges 5 | 50
Short hands 5 | 50
Unipolar Depression 5 | 250
Uranostaphyloschisis 5 | 167
Vascular disease 5 | 319
cutaneous lupus erythematosus 5 | 1,057
esophageal adenocarcinoma 5 | 737
primary Sjogren syndrome 5 | 735
Glaucoma 4 | 239
spina bifida 4 | 1,074

Tissue

Endocrine System 58 | 18,159
Digestive Tract 57 | 17,369
Female tissues 56 | 17,400
Male tissues 56 | 17,142
Nervous System 55 | 16,725
Skin and soft tissues 55 | 17,230
Liver and Pancreas 54 | 16,750
Blood and immune system 53 | 16,909
Respiratory system 53 | 16,393
Urinary Tract 53 | 16,678
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 28 | 12,091
Transcription Factor 19 | 1,400
Enzyme 10 | 4,145
Kinase 1 | 634
Nuclear Receptor 1 | 48

GO Process

cartilage development 59 | 59
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Integrin beta-8 ITGB8 Tbio Non-IDG -1.47947 27.7 99
Hyaluronidase-1 HYAL1 Tbio Enzyme -1.88328 77.3 220
Collagen alpha-1(II) chain COL2A1 Tbio Non-IDG -2.89229 724.4 424
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Metalloproteinase inhibitor 1 TIMP1 Tbio Enzyme -3.57247 3714.8 810
Protein Wnt-5a WNT5A Tbio Non-IDG -2.77525 650.2 321
Interleukin-17F IL17F Tbio Non-IDG -2.59592 347.9 586
Mothers against decapentaplegic homolog 5 SMAD5 Tbio Transcription Factor -2.16078 121.7 359