Development Level

Tbio 16 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal eyelid morphology 1 | 7
abnormal gait 1 | 69
abnormal tail morphology 1 | 25
absent vibrissae 1 | 12
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased circulating alkaline... 1 | 46
decreased circulating total pr... 1 | 49
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
eyelids fail to open 1 | 3
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
narrow eye opening 1 | 12
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 17 | 11,493
glioblastoma 10 | 5,792
ovarian cancer 10 | 8,520
Autosomal recessive predisposition 8 | 1,442
Cancer 8 | 2,499
atypical teratoid / rhabdoid tumor 8 | 5,112
group 3 medulloblastoma 8 | 4,104
lung cancer 8 | 4,740
psoriasis 8 | 6,694
ependymoma 7 | 4,679
malignant mesothelioma 7 | 3,232
medulloblastoma, large-cell 7 | 6,241
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Orbital separation excessive 6 | 244
cystic fibrosis 6 | 1,696
osteosarcoma 6 | 7,950
pituitary cancer 6 | 1,972
Breast cancer 5 | 3,578
Broad flat nasal bridge 5 | 236
Concave bridge of nose 5 | 195
Congenital deafness 5 | 185
Craniofacial Abnormalities 5 | 151
Deafness 5 | 198
Depressed nasal bridge 5 | 195
Depressed nasal root/bridge 5 | 195
Hearing Loss, Partial 5 | 185
Hypoplastic feet 5 | 66
Kidney cancer 5 | 2,613
Low set ears 5 | 181
Nasal bridge wide 5 | 236
Short stature 5 | 531
adult high grade glioma 5 | 3,801
hearing impairment 5 | 199
lung adenocarcinoma 5 | 2,716
ANONYCHIA 4 | 20
Anteverted nostril 4 | 191
Astrocytoma, Pilocytic 4 | 3,081
Brachydactyly 4 | 156
Cleft Palate 4 | 271
Congenital Epicanthus 4 | 177
Congenital clubfoot 4 | 109
Decreased projection of midface 4 | 105
Exophthalmos 4 | 112
Flat face 4 | 52
Hypotrophic malar bone 4 | 129
Hypotrophic midface 4 | 105
Kidney disease 4 | 430
Malar flattening 4 | 129
Micromelia 4 | 58
Midface retrusion 4 | 105
Pick disease 4 | 1,894
Prominent eyes 4 | 96
Prominent globes 4 | 96
Protruding eyes 4 | 96
Short limb dwarfism, disproportionate 4 | 22
Short neck 4 | 140
Small midface 4 | 105
Umbilical hernia 4 | 93
Uranostaphyloschisis 4 | 167
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
Acquired scoliosis 3 | 281
Alzheimer's disease 3 | 658
Arthralgia 3 | 90
Arthritis 3 | 290
Big calvaria 3 | 147
Bilateral fifth finger clinodactyly 3 | 110
Curvature of little finger 3 | 110
Curvature of spine 3 | 282
Delayed bone age 3 | 136
Dull intelligence 3 | 645
Frontal bossing 3 | 157
Glaucoma 3 | 239
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Long philtrum 3 | 137
Lung Neoplasms 3 | 232
Melanoma 3 | 711
Osteoarthritis 3 | 184
Osteochondrodysplasias 3 | 72
Polyhydramnios 3 | 108
Short nose 3 | 132
Small nose 3 | 132
Thin rib 3 | 21
Wide anterior fontanel 3 | 44
X-linked cerebral adrenoleukodystrophy 3 | 116
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
non-small cell lung cancer 3 | 2,890
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035

Tissue

Endocrine System 17 | 18,159
Skin and soft tissues 17 | 17,230
Digestive Tract 16 | 17,369
Male tissues 16 | 17,142
Urinary Tract 16 | 16,678
Female tissues 15 | 17,400
Nervous System 15 | 16,725
Liver and Pancreas 14 | 16,750
Blood and immune system 13 | 16,909
Respiratory system 13 | 16,393
Cardiovascular System 10 | 15,192

Target Family

Non-IDG 10 | 12,091
Transcription Factor 6 | 1,400
Kinase 3 | 634
Nuclear Receptor 1 | 48

GO Process

cartilage condensation 20 | 20
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-1(XI) chain COL11A1 Tbio Non-IDG -2.15516 138.4 96
Polycystin-1 PKD1 Tbio Non-IDG -2.60276 379.9 123
Homeobox protein BarH-like 2 BARX2 Tbio Transcription Factor -1.17761 19.7 66
Bone morphogenetic protein receptor type-1B BMPR1B Tchem Kinase -2.00303 86.8 498
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Matrix Gla protein MGP Tbio Non-IDG -2.97429 878.1 151
Fibroblast growth factor 4 FGF4 Tbio Non-IDG -2.60388 394.1 327
Fibroblast growth factor 6 FGF6 Tbio Non-IDG -1.56137 40.2 113
Homeobox protein unc-4 homolog UNCX Tbio Transcription Factor -1.05135 11.6 106
N-myc proto-oncogene protein MYCN Tbio Transcription Factor -3.35747 2111.2 242