Development Level

Tbio 4 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 1 | 220
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
increased anti-nuclear antigen... 1 | 19
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
male infertility 1 | 123

Disease

osteosarcoma 5 | 7,950
Carcinoma 2 | 11,493
ependymoma 2 | 4,679
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
3-Methylglutaconic aciduria type 2 1 | 2
Abnormal mitochondria morphology 1 | 1
Abnormal vision 1 | 52
Abnormal visual evoked potential 1 | 26
Abnormal visual pursuit 1 | 14
Abnormality of metabolism/homeostasis 1 | 134
Aceruloplasminemia 1 | 16
Action Tremor 1 | 22
Agranulocytosis 1 | 6
Anomalous left coronary artery from the pulmonary artery 1 | 5
Cachexia 1 | 50
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Cardiomyopathy 1 | 116
Centronuclear myopathy 1 | 27
Cerebellar Dysmetria 1 | 56
Childhood onset 1 | 38
Class III malocclusion 1 | 78
Clumsiness 1 | 7
Conduction disorder of the heart 1 | 79
Congenital deafness 1 | 185
Congestive heart failure 1 | 113
Deafness 1 | 198
Degenerative brain disorder 1 | 100
Deglutition Disorders 1 | 132
Disease of cellular proliferation 1 | 3
Disorder of skeletal muscle 1 | 1
Dysdiadochokinesis 1 | 25
EKG abnormalities 1 | 78
EMG: chronic denervation signs 1 | 4
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Endocardial Fibroelastosis 1 | 9
Enophthalmos 1 | 75
Familial isolated dilated cardiomyopathy 1 | 41
Fatigue 1 | 182
Frontotemporal cerebral atrophy 1 | 8
Gait, Unsteady 1 | 29
Global brain atrophy 1 | 7
Hearing Loss, Partial 1 | 185
Heart failure 1 | 162
Hyperactive behavior 1 | 91
Hypertrophic Cardiomyopathy 1 | 117
Hypertrophy of lower jaw 1 | 78
Impaired smooth pursuit 1 | 14
Impulsive Behavior 1 | 9
Increased size of mandible 1 | 78
Intermittent lactic acidemia 1 | 1
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
Left ventricular noncompaction 1 | 26
Leigh disease 1 | 100
Mandibular hyperplasia 1 | 78
Melkersson-Rosenthal syndrome 1 | 4
Mental deterioration 1 | 32
Mood swings 1 | 77
Morphological abnormality of the pyramidal tract 1 | 12
Muscle Rigidity 1 | 49
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neuroaxonal dystrophy 1 | 8
Neurodegeneration with brain iron accumulation 1 | 20
Neurodegeneration with brain iron accumulation 2a 1 | 3
Neurodegeneration with brain iron accumulation 2b 1 | 2
Neurodegenerative Disorders 1 | 79
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Neutropenia 1 | 72
Neutrophil abnormality 1 | 20
Nevus 1 | 19
Nonorganic psychosis 1 | 84
Oculocerebrorenal syndrome 1 | 29
Parkinsonian Disorders 1 | 56
Poor growth 1 | 114
Postural instability 1 | 19
Pyramidal sign 1 | 29
Pyramidal tract disease 1 | 12
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Recurrent infections in infancy and early childhood 1 | 1
Reduced concentration span 1 | 9
Round face 1 | 45
Round, full face 1 | 45
Sengers syndrome 1 | 18
Spastic Quadriplegia 1 | 42
Sunken eyes 1 | 63
Supranuclear gaze palsy 1 | 6
Supratentorial atrophy 1 | 94
Talipes Calcaneovalgus 1 | 6
Terminal tremor 1 | 20
Tremor 1 | 113
Very poor growth 1 | 114
X- linked recessive 1 | 110
hearing impairment 1 | 199
inflammatory breast cancer 1 | 286
mandibular excess (physical finding) 1 | 78

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 1 | 12,091
Transporter 1 | 473

GO Process

cardiolipin biosynthetic proce... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cardiolipin synthase (CMP-forming) CRLS1 Tbio Enzyme -0.87118 6.24 100
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 PTPMT1 Tbio Enzyme -1.36243 23.0 109
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial PGS1 Tdark Enzyme -0.35218 2.20 123
Phosphatidate cytidylyltransferase, mitochondrial TAMM41 Tbio Enzyme -0.79472 6.33 123
Long-chain fatty acid transport protein 1 SLC27A1 Tchem Transporter -2.18464 151.5 79
85/88 kDa calcium-independent phospholipase A2 PLA2G6 Tchem Enzyme -2.50583 353.3 143
Tafazzin TAZ Tbio Non-IDG -2.58927 388.5 321