Development Level

Tbio 2 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

decreased bone mineral content 1 | 151
decreased lean body mass 1 | 135
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 3 | 11,493
Breast cancer 2 | 3,578
Cancer 2 | 2,499
atypical teratoid / rhabdoid tumor 2 | 5,112
group 3 medulloblastoma 2 | 4,104
lung adenocarcinoma 2 | 2,716
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
Abnormality of the iris 1 | 14
Acquired flat foot 1 | 72
Acquired scoliosis 1 | 281
Alzheimer's disease 1 | 658
Anxiety Disorders 1 | 38
Aortic Aneurysm, Thoracic 1 | 8
Aortic Valve Insufficiency 1 | 40
Aortic aneurysm 1 | 38
Aortic aneurysm, familial thoracic 3 1 | 13
Arachnodactyly 1 | 49
Arterial tortuosity 1 | 5
Ascending aortic dissection 1 | 13
Astrocytoma, Pilocytic 1 | 3,081
Autoimmune Diseases 1 | 67
Autoimmune Diseases of the Nervous System 1 | 2
Bladder Neoplasm 1 | 112
Bone Diseases, Developmental 1 | 27
Byzanthine arch palate 1 | 194
Cardiomegaly 1 | 116
Cataract 1 | 297
Chest Pain 1 | 38
Cholangitis 1 | 32
Colonic Neoplasms 1 | 142
Congenital Heart Defects 1 | 58
Congenital musculoskeletal anomalies 1 | 5
Connective tissue disease 1 | 62
Coronary artery disease 1 | 268
Craniofacial Abnormalities 1 | 151
Curvature of spine 1 | 282
Cutis marmorata 1 | 32
Cyanosis 1 | 17
Cystic medial necrosis of aorta 1 | 13
Descending aortic dissection 1 | 13
Diabetic retinopathy 1 | 56
Dissection of aorta 1 | 9
Dural ectasia 1 | 4
Dyspnea on exertion 1 | 24
Dyspnea, Paroxysmal 1 | 13
Ecchymosis 1 | 66
Endometriosis 1 | 540
Eye Abnormalities 1 | 35
Familial thoracic aortic aneurysm and aortic dissection 1 | 13
Flatfoot 1 | 73
Glaucoma 1 | 239
Heart Defects, Congenital 1 | 37
Hernia, Inguinal 1 | 89
Hypertensive disease 1 | 292
Impaired left ventricular function 1 | 16
Increase in blood pressure 1 | 119
Increased tendency to bruise 1 | 66
Joint hyperflexibility 1 | 78
Kidney cancer 1 | 2,613
Left-Sided Heart Failure 1 | 16
Limb Deformities, Congenital 1 | 16
Loeys-Dietz Aortic Aneurysm Syndrome 1 | 13
Loeys-Dietz syndrome 1 | 23
Loeys-Dietz syndrome 4 1 | 4
Macular holes 1 | 11
Mesothelioma, Malignant 1 | 105
Microcephaly 1 | 166
Mitral Valve Prolapse Syndrome 1 | 39
Multiple Sclerosis 1 | 540
Musculoskeletal Abnormalities 1 | 6
Myopia 1 | 176
Polycystic ovary syndrome 1 | 360
Proliferative vitreoretinopathy 1 | 17
Retinal Detachment 1 | 51
Retrognathia 1 | 54
Sternal anomalies 1 | 19
Tall stature 1 | 34
Thoracic aortic aneurysm 1 | 15
Ureteral obstruction 1 | 33
Urinary Bladder Neoplasms 1 | 114
adult high grade glioma 1 | 3,801
cystic fibrosis 1 | 1,696
glioblastoma 1 | 5,792
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
interstitial cystitis 1 | 2,312
invasive ductal carcinoma 1 | 2,951
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
non-small cell lung cancer 1 | 2,890
non-small cell lung carcinoma 1 | 317
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
primary Sjogren syndrome 1 | 735
subependymal giant cell astrocytoma 1 | 2,287
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 1 | 4,145
Non-IDG 1 | 12,091
Transcription Factor 1 | 1,400

GO Process

cardioblast differentiation 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eomesodermin homolog EOMES Tbio Transcription Factor -2.37902 230.4 333
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Endothelin-converting enzyme 2 ECE2 Tchem Enzyme -1.44165 26.8 84