Development Level

Tbio 28 | 11,445
Tclin 12 | 613
Tchem 5 | 1,598

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 3 | 278
abnormal behavior 2 | 298
hyperactivity 2 | 148
increased startle reflex 2 | 112
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
abnormal skin morphology 1 | 50
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
edema 1 | 59
increased circulating LDL chol... 1 | 13
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
long tibia 1 | 25

Disease

Carcinoma 28 | 11,493
psoriasis 24 | 6,694
Cardiomyopathy 22 | 116
Hypertrophic Cardiomyopathy 18 | 117
medulloblastoma, large-cell 18 | 6,241
glioblastoma 17 | 5,792
ovarian cancer 17 | 8,520
Dilated cardiomyopathy 16 | 56
atypical teratoid / rhabdoid tumor 16 | 5,112
Cardiomyopathy, Dilated 15 | 83
Familial isolated dilated cardiomyopathy 14 | 41
LEFT VENTRICULAR NONCOMPACTION 10 14 | 40
LEFT VENTRICULAR NONCOMPACTION 8 14 | 40
adult high grade glioma 14 | 3,801
Congestive heart failure 13 | 113
group 3 medulloblastoma 12 | 4,104
lung adenocarcinoma 12 | 2,716
lung cancer 12 | 4,740
osteosarcoma 12 | 7,950
Autosomal recessive predisposition 11 | 1,442
Breast cancer 11 | 3,578
Cardiac Arrhythmia 11 | 103
acute quadriplegic myopathy 11 | 1,158
malignant mesothelioma 11 | 3,232
Astrocytoma, Pilocytic 10 | 3,081
Atrial Fibrillation 10 | 124
Epilepsy 10 | 792
Familial atrial fibrillation 10 | 23
Heart disease 10 | 306
Heart failure 10 | 162
Kidney cancer 10 | 2,613
Myopathy 10 | 185
Cancer 9 | 2,499
Left ventricular noncompaction 9 | 26
ependymoma 9 | 4,679
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 8 | 21
Cardiac conduction abnormalities 8 | 78
Conduction disorder of the heart 8 | 79
EKG abnormalities 8 | 78
Electrocardiogram abnormal 8 | 81
Electrocardiogram change 8 | 78
Pick disease 8 | 1,894
colon cancer 8 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
oligodendroglioma 8 | 2,850
primitive neuroectodermal tumor 8 | 3,035
Brugada syndrome 7 | 29
Cardiomegaly 7 | 116
Cardiomyopathies 7 | 110
Cardiomyopathy, Hypertrophic, Familial 7 | 9
Duchenne muscular dystrophy 7 | 601
Heart conduction disease 7 | 83
Liver cancer 7 | 604
Muscle hypotonia 7 | 571
Myocardial Infarction 7 | 151
Sudden Cardiac Death 7 | 29
Sudden death 7 | 16
Tachycardia, Ventricular 7 | 22
diabetes mellitus 7 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
invasive ductal carcinoma 7 | 2,951
pancreatic cancer 7 | 2,398
pituitary cancer 7 | 1,972
subependymal giant cell astrocytoma 7 | 2,287
Cardiomyopathy, Hypertrophic 6 | 24
Hypertension 6 | 396
Long QT syndrome 6 | 39
Sudden infant death syndrome 6 | 32
ductal carcinoma in situ 6 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
non-small cell lung cancer 6 | 2,890
Acquired scoliosis 5 | 281
Amyotrophic lateral sclerosis 5 | 451
Atrioventricular block 5 | 35
Cardiomyopathy, Familial Hypertrophic, 1 5 | 6
Cardiomyopathy, Familial Hypertrophic, 1 (disorder) 5 | 7
Creatine phosphokinase serum increased 5 | 110
Curvature of spine 5 | 282
Elevated creatine kinase 5 | 110
Endometrial cancer 5 | 311
Fatigue 5 | 182
Intellectual disability 5 | 1,016
Melanoma 5 | 711
Restrictive cardiomyopathy 5 | 11
Schizophrenia 5 | 1,160
Seizures 5 | 596
Skin cancer 5 | 469
Syncope 5 | 22
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
interstitial cystitis 5 | 2,312
tuberculosis 5 | 2,010
Cardiovascular Diseases 4 | 59
Parkinson's disease 4 | 392
Status Epilepticus 4 | 98
adrenocortical carcinoma 4 | 1,428
dermatomyositis 4 | 966
fibroadenoma 4 | 559
juvenile dermatomyositis 4 | 1,187

Tissue

Blood and immune system 44 | 16,909
Cardiovascular System 44 | 15,192
Digestive Tract 44 | 17,369
Endocrine System 44 | 18,159
Female tissues 44 | 17,400
Male tissues 44 | 17,142
Skin and soft tissues 44 | 17,230
Liver and Pancreas 43 | 16,750
Urinary Tract 42 | 16,678
Nervous System 41 | 16,725
Respiratory system 38 | 16,393

Target Family

Non-IDG 23 | 12,091
Ion Channel 8 | 344
Kinase 7 | 634
Transporter 4 | 473
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

GO Process

cardiac muscle contraction 45 | 45
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin light chain 1/3, skeletal muscle isoform MYL1 Tbio Non-IDG -2.11698 129.3 109
Potassium voltage-gated channel subfamily E regulatory beta subunit 5 KCNE5 Tbio Non-IDG -0.91945 8.20 84
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Sodium channel subunit beta-4 SCN4B Tbio Ion Channel -1.42029 24.1 85
RelA-associated inhibitor PPP1R13L Tbio Non-IDG -1.76131 64.5 185
Potassium voltage-gated channel subfamily H member 2 KCNH2 Tclin Ion Channel -3.22575 1653.9 243
Titin TTN Tbio Kinase -3.24415 1743.0 123
Cysteine and glycine-rich protein 3 CSRP3 Tbio Non-IDG -2.00418 105.2 236
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
Sodium/potassium-transporting ATPase subunit alpha-3 ATP1A3 Tclin Transporter -2.24223 170.0 132