Development Level

Tchem 17 | 1,890
Tbio 14 | 10,625
Tclin 12 | 602
Tdark 2 | 7,003

Collection

Eligible Ion Channel Proteins 20 | 117

IMPC Term

decreased body weight 2 | 174
abnormal embryo size 1 | 112
abnormal facial morphology 1 | 9
abnormal head morphology 1 | 10
abnormal placenta vasculature 1 | 2
cyanosis 1 | 6
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased lumbar vertebrae num... 1 | 62
decreased total body fat amoun... 1 | 186
edema 1 | 11
hemorrhage 1 | 12
increased bone mineral content 1 | 92
increased circulating fructosa... 1 | 11
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
prenatal lethality 1 | 16
preweaning lethality, complete... 1 | 633
respiratory system phenotype 1 | 2

Disease

medulloblastoma, large-cell 24 | 6,234
atypical teratoid / rhabdoid tumor 23 | 4,369
glioblastoma 21 | 5,572
primitive neuroectodermal tumor 17 | 3,031
oligodendroglioma 16 | 2,849
osteosarcoma 16 | 7,933
pilocytic astrocytoma 16 | 3,086
ependymoma 15 | 2,514
psoriasis 15 | 6,685
ovarian cancer 14 | 8,484
adult high grade glioma 13 | 2,148
Carcinoma 12 | 2,147
Long QT syndrome 12 | 52
subependymal giant cell astrocytoma 12 | 2,287
Atrial Fibrillation 11 | 110
Pick disease 11 | 1,893
astrocytic glioma 11 | 2,241
medulloblastoma 11 | 1,524
pediatric high grade glioma 11 | 2,712
lung cancer 10 | 4,466
Brugada syndrome 9 | 26
Short QT syndrome 9 | 12
lung carcinoma 9 | 2,844
malignant mesothelioma 9 | 3,162
pituitary cancer 9 | 1,972
Epilepsy 8 | 346
Heart disease 8 | 279
Timothy syndrome 8 | 12
posterior fossa group A ependymoma 8 | 1,511
Brugada Syndrome (disorder) 7 | 15
Congenital long QT syndrome 7 | 8
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
invasive ductal carcinoma 7 | 2,950
lung adenocarcinoma 7 | 2,713
Romano-Ward Syndrome 6 | 12
group 3 medulloblastoma 6 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
Angina pectoris 5 | 21
Eaton-Lambert syndrome 5 | 40
Familial atrial fibrillation 5 | 16
Hypokalemia 5 | 40
Multiple Sclerosis 5 | 498
ductal carcinoma in situ 5 | 1,745
sonic hedgehog group medulloblastoma 5 | 1,482
Atrial Fibrillation Adverse Event 4 | 4
Bipolar Disorder 4 | 266
Cardioversion of Atrial Fibrillation 4 | 9
Heart conduction disease 4 | 65
Hypertensive disorder 4 | 58
Malignant hyperthermia 4 | 25
Prinzmetal angina 4 | 6
Rheumatoid Arthritis 4 | 1,160
Sudden infant death syndrome 4 | 33
Type 2 diabetes mellitus 4 | 189
active Crohn's disease 4 | 918
adrenocortical carcinoma 4 | 1,427
colon cancer 4 | 1,475
interstitial cystitis 4 | 2,299
non-small cell lung cancer 4 | 2,798
ulcerative colitis 4 | 2,087
Acquired long QT syndrome 3 | 3
Breast cancer 3 | 3,094
Cardiac Arrhythmia 3 | 20
Cerebellar Ataxia 3 | 72
Down syndrome 3 | 548
Hypertensive disease 3 | 193
Hypokalemic periodic paralysis 3 | 13
Parkinson's disease 3 | 364
Paroxysmal supraventricular tachycardia 3 | 11
Postherpetic neuralgia 3 | 12
Prevention of Paroxysmal Supraventricular Tachycardia 3 | 4
Schizophrenia 3 | 501
Schnyder corneal dystrophy 3 | 23
Subarachnoid intracranial hemorrhage 3 | 3
Torsades de Pointes 3 | 5
Ventricular Fibrillation 3 | 10
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
breast carcinoma 3 | 1,614
gastric carcinoma 3 | 832
pancreatic cancer 3 | 2,300
primary pancreatic ductal adenocarcinoma 3 | 1,271
Alzheimer's disease 2 | 644
Amyotrophic Lateral Sclerosis 2 | 431
Arsenic Poisoning 2 | 59
Atopic dermatitis 2 | 944
Cerebrovascular accident 2 | 44
Colonic Neoplasms 2 | 126
Dermatologic disorders 2 | 65
Hypertension 2 | 287
Life-Threatening Ventricular Tachycardia 2 | 15
Muscle Weakness 2 | 92
Neuralgia 2 | 16
Thyrotoxicosis 2 | 38
active ulcerative colitis 2 | 477
acute quadriplegic myopathy 2 | 1,157
cystic fibrosis 2 | 1,665
fibroadenoma 2 | 557
progressive supranuclear palsy 2 | 674

Tissue

Cardiovascular System 45 | 17,958
Digestive Tract 45 | 18,473
Endocrine System 45 | 18,512
Female tissues 45 | 18,647
Liver and Pancreas 45 | 18,136
Nervous System 45 | 18,561
Urinary Tract 45 | 18,444
Blood and immune system 44 | 17,995
Skin and soft tissues 44 | 18,115
Male tissues 43 | 17,969
Respiratory system 43 | 17,484

Target Family

Ion Channel 42 | 341
Enzyme 1 | 4,146
Non-IDG 1 | 11,971
Transcription Factor 1 | 1,400

GO Process

cardiac conduction 45 | 45
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Voltage-dependent calcium channel gamma-7 subunit CACNG7 Tchem Ion Channel -0.48027 2.02 53
Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 Tchem Ion Channel -1.00872 12.4 65
Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 Tchem Ion Channel -1.43080 25.0 426
Potassium voltage-gated channel subfamily E member 1 KCNE1 Tbio Ion Channel -2.63112 407.4 169
Potassium voltage-gated channel subfamily E member 2 KCNE2 Tbio Ion Channel -1.96950 86.9 104
Inward rectifier potassium channel 4 KCNJ4 Tchem Ion Channel -1.87814 80.2 193
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.30673 205.2 153
Inward rectifier potassium channel 2 KCNJ2 Tchem Ion Channel -2.32321 207.3 201
ATP-sensitive inward rectifier potassium channel 14 KCNJ14 Tdark Ion Channel -1.13670 14.7 0