Development Level

Tbio 85 | 11,651
Tdark 20 | 6,593
Tchem 16 | 1,388
Tclin 7 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal lens morphology 4 | 81
abnormal retina morphology 3 | 71
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased lean body mass 3 | 172
preweaning lethality, incomple... 3 | 499
abnormal bone mineralization 2 | 38
abnormal kidney morphology 2 | 65
abnormal response to tactile s... 2 | 17
abnormal spleen morphology 2 | 55
abnormal startle reflex 2 | 15
cataract 2 | 92
decreased circulating alkaline... 2 | 46
decreased circulating glucose ... 2 | 126
decreased leukocyte cell numbe... 2 | 73
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
small kidney 2 | 16
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal esophagus morphology 1 | 5
abnormal seminal vesicle morph... 1 | 114
abnormal urinary bladder morph... 1 | 11
absent pinna reflex 1 | 23
bleb 1 | 2
cardiovascular system phenotyp... 1 | 36
cystolithiasis 1 | 3
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
hydrometra 1 | 53
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
long tibia 1 | 25
polycystic kidney 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened RR interval 1 | 17
thrombocytosis 1 | 27

Disease

Carcinoma 89 | 11,493
ovarian cancer 50 | 8,520
psoriasis 50 | 6,694
osteosarcoma 48 | 7,950
glioblastoma 36 | 5,792
medulloblastoma, large-cell 35 | 6,241
ependymoma 33 | 4,679
group 3 medulloblastoma 32 | 4,104
lung cancer 31 | 4,740
atypical teratoid / rhabdoid tumor 29 | 5,112
lung adenocarcinoma 27 | 2,716
Breast cancer 26 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
non-small cell lung cancer 22 | 2,890
Autosomal recessive predisposition 21 | 1,442
Cancer 21 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
primitive neuroectodermal tumor 20 | 3,035
adult high grade glioma 19 | 3,801
pancreatic cancer 19 | 2,398
tuberculosis 19 | 2,010
Astrocytoma, Pilocytic 18 | 3,081
diabetes mellitus 18 | 1,728
lung carcinoma 17 | 2,843
malignant mesothelioma 17 | 3,232
pediatric high grade glioma 17 | 1,064
astrocytic glioma 14 | 2,597
invasive ductal carcinoma 14 | 2,951
pituitary cancer 14 | 1,972
ulcerative colitis 14 | 1,819
colon cancer 13 | 1,478
ductal carcinoma in situ 13 | 1,745
oligodendroglioma 13 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
non primary Sjogren syndrome sicca 12 | 891
Obesity 11 | 678
astrocytoma 11 | 1,146
breast carcinoma 11 | 1,638
interstitial cystitis 11 | 2,312
Kidney cancer 10 | 2,613
nasopharyngeal carcinoma 10 | 1,058
primary pancreatic ductal adenocarcinoma 10 | 1,109
subependymal giant cell astrocytoma 10 | 2,287
Multiple myeloma 9 | 1,332
cystic fibrosis 9 | 1,696
group 4 medulloblastoma 9 | 1,855
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
Muscle hypotonia 8 | 571
Short stature 8 | 531
active Crohn's disease 8 | 922
active ulcerative colitis 8 | 764
spina bifida 8 | 1,074
Schizophrenia 7 | 1,160
cutaneous lupus erythematosus 7 | 1,057
gastric carcinoma 7 | 807
mucosa-associated lymphoid tissue lymphoma 7 | 484
Atopic dermatitis 6 | 952
Concave bridge of nose 6 | 195
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Hyperglycemia 6 | 137
Hypoglycemia 6 | 152
Intellectual disability 6 | 1,016
Liver Cirrhosis, Experimental 6 | 769
Melanoma 6 | 711
Mucopolysaccharidosis 6 | 26
Pick disease 6 | 1,894
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
esophageal adenocarcinoma 6 | 737
fibroadenoma 6 | 559
Acquired scoliosis 5 | 281
Bipolar Disorder 5 | 666
Breast Neoplasms 5 | 445
Curvature of spine 5 | 282
Diabetes mellitus type 2 5 | 69
Epilepsy 5 | 792
Failure to gain weight 5 | 365
Kidney disease 5 | 430
Mammary Neoplasms 5 | 425
Osteoarthritis 5 | 184
Pediatric failure to thrive 5 | 365
Prostatic Neoplasms 5 | 495
Rheumatoid arthritis 5 | 1,191
Waldenstrons macroglobulinemia 5 | 765
atypical teratoid/rhabdoid tumor 5 | 357
dermatomyositis 5 | 966
Alzheimer's disease 4 | 658
Asthma 4 | 385
Cutis Laxa 4 | 39
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Diabetes Mellitus, Type 2 4 | 142
Duchenne muscular dystrophy 4 | 601
Dull intelligence 4 | 645
Poor school performance 4 | 645
Type 2 diabetes mellitus 4 | 272
nephrosclerosis 4 | 333

Tissue

Endocrine System 124 | 18,159
Digestive Tract 122 | 17,369
Female tissues 122 | 17,400
Blood and immune system 119 | 16,909
Skin and soft tissues 119 | 17,230
Liver and Pancreas 117 | 16,750
Male tissues 117 | 17,142
Nervous System 114 | 16,725
Urinary Tract 114 | 16,678
Respiratory system 110 | 16,393
Cardiovascular System 105 | 15,192

Target Family

Enzyme 105 | 4,145
Transporter 9 | 473
Non-IDG 7 | 12,091
Kinase 6 | 634
GPCR 1 | 408

GO Process

carbohydrate metabolic process 128 | 128
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-amylase 2B AMY2B Tbio Enzyme -2.04365 112.9 137
Polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 Tbio Enzyme -2.80894 644.1 124
Aldehyde dehydrogenase X, mitochondrial ALDH1B1 Tbio Enzyme -1.73034 52.5 194
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 B3GAT3 Tbio Enzyme -1.43805 32.2 112
Pancreatic alpha-amylase AMY2A Tclin Enzyme -2.93089 824.2 250
Lactosylceramide alpha-2,3-sialyltransferase ST3GAL5 Tbio Enzyme -1.82966 68.2 113
Hyaluronidase-1 HYAL1 Tbio Enzyme -1.88328 77.3 220
Alpha-1,4-N-acetylglucosaminyltransferase A4GNT Tbio Enzyme -1.00664 3.51 235
N-acetylneuraminate lyase NPL Tbio Enzyme -3.10700 1259.2 86
L-lactate dehydrogenase A-like 6B LDHAL6B Tbio Enzyme -1.70845 50.7 108