Development Level

Tbio 75 | 10,625
Tchem 24 | 1,890
Tdark 21 | 7,003
Tclin 6 | 602

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 633
increased grip strength 3 | 83
abnormal bone mineralization 2 | 55
abnormal lens morphology 2 | 73
abnormal response to tactile s... 2 | 16
abnormal retina morphology 2 | 100
abnormal startle reflex 2 | 14
decreased circulating HDL chol... 2 | 77
decreased circulating alkaline... 2 | 41
decreased circulating glucose ... 2 | 121
decreased leukocyte cell numbe... 2 | 54
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
increased bone mineral density 2 | 52
increased circulating alkaline... 2 | 119
increased lean body mass 2 | 107
short tibia 2 | 82
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal esophagus morphology 1 | 4
abnormal kidney morphology 1 | 30
abnormal retinal pigmentation 1 | 61
abnormal seminal vesicle morph... 1 | 47
abnormal spleen morphology 1 | 36
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 35
decreased B cell number 1 | 30
decreased CD103-positive CD11b... 1 | 2
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
decreased spleen weight 1 | 13
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased effector memory CD8-... 1 | 14
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased memory CD4-positive,... 1 | 3
long tibia 1 | 13
small kidney 1 | 10

Disease

osteosarcoma 48 | 7,933
psoriasis 48 | 6,685
ovarian cancer 45 | 8,491
medulloblastoma, large-cell 35 | 6,234
glioblastoma 34 | 5,572
lung cancer 29 | 4,473
lung adenocarcinoma 28 | 2,714
atypical teratoid / rhabdoid tumor 25 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,956
Breast cancer 22 | 3,098
Cancer 21 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
malignant mesothelioma 21 | 3,163
non-small cell lung cancer 21 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
diabetes mellitus 19 | 1,663
primitive neuroectodermal tumor 19 | 3,031
pediatric high grade glioma 18 | 2,712
lung carcinoma 17 | 2,844
pancreatic cancer 17 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,795
pilocytic astrocytoma 17 | 3,086
ependymoma 16 | 2,514
ulcerative colitis 16 | 2,087
adult high grade glioma 15 | 2,148
colon cancer 14 | 1,475
group 3 medulloblastoma 14 | 2,254
interstitial cystitis 14 | 2,299
invasive ductal carcinoma 14 | 2,950
astrocytic glioma 13 | 2,241
group 4 medulloblastoma 13 | 1,875
oligodendroglioma 13 | 2,849
tuberculosis 13 | 1,563
astrocytoma 12 | 1,493
Obesity 11 | 616
ductal carcinoma in situ 11 | 1,745
pituitary cancer 11 | 1,972
posterior fossa group A ependymoma 11 | 1,511
subependymal giant cell astrocytoma 11 | 2,287
Carcinoma 10 | 2,147
cystic fibrosis 10 | 1,670
medulloblastoma 10 | 1,524
non primary Sjogren syndrome sicca 10 | 840
posterior fossa group B ependymoma 10 | 1,530
breast carcinoma 9 | 1,614
gastric carcinoma 9 | 832
nasopharyngeal carcinoma 9 | 1,056
Hyperglycemia 8 | 120
IGA Glomerulonephritis 8 | 454
Multiple myeloma 8 | 1,327
sonic hedgehog group medulloblastoma 8 | 1,482
active ulcerative colitis 7 | 477
cutaneous lupus erythematosus 7 | 1,056
esophageal adenocarcinoma 7 | 737
mucosa-associated lymphoid tissue lymphoma 7 | 480
primary pancreatic ductal adenocarcinoma 7 | 1,271
spina bifida 7 | 1,064
Atopic dermatitis 6 | 944
Mammary Neoplasms 6 | 410
Mucopolysaccharidosis 6 | 24
Pick disease 6 | 1,893
Waldenstrons macroglobulinemia 6 | 764
active Crohn's disease 6 | 918
acute quadriplegic myopathy 6 | 1,157
adrenocortical carcinoma 6 | 1,427
atypical teratoid/rhabdoid tumor 6 | 1,095
dermatomyositis 6 | 966
fibroadenoma 6 | 557
Diabetes mellitus type 2 5 | 69
Gaucher's disease 5 | 25
Kidney disease 5 | 397
Multiple Sclerosis 5 | 498
nephrosclerosis 5 | 329
Asthma 4 | 349
Barrett's esophagus 4 | 185
Diabetes Mellitus, Experimental 4 | 106
Diabetes Mellitus, Non-Insulin-Dependent 4 | 161
Diarrhea 4 | 155
Duchenne muscular dystrophy 4 | 602
Hypoglycemia 4 | 81
Liver carcinoma 4 | 217
Metabolic syndrome X 4 | 155
Neurodegenerative disease 4 | 383
Osteoporosis 4 | 259
Parkinson's disease 4 | 364
Rheumatoid Arthritis 4 | 1,170
head and neck cancer and chronic obstructive pulmonary disease 4 | 237
non-small cell lung carcinoma 4 | 413
progressive supranuclear palsy 4 | 674
tuberculosis and treatment for 3 months 4 | 327
Alzheimer's disease 3 | 644
Male infertility 3 | 170
Prostatic Neoplasms 3 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic lymphocytic leukemia 3 | 244
chronic rhinosinusitis 3 | 512
hepatocellular carcinoma 3 | 550
inflammatory breast cancer 3 | 404
pancreatic carcinoma 3 | 567
periodontitis 3 | 269

Tissue

Digestive Tract 124 | 18,472
Liver and Pancreas 123 | 18,135
Nervous System 123 | 18,560
Endocrine System 122 | 18,511
Female tissues 122 | 18,646
Male tissues 122 | 17,968
Urinary Tract 122 | 18,443
Cardiovascular System 121 | 17,957
Skin and soft tissues 121 | 18,114
Blood and immune system 120 | 17,994
Respiratory system 118 | 17,483

Target Family

Enzyme 101 | 4,146
Transporter 9 | 473
Non-IDG 8 | 11,969
Kinase 7 | 634
GPCR 1 | 408

GO Process

carbohydrate metabolic process 126 | 126
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Oviduct-specific glycoprotein OVGP1 Tbio Enzyme -2.24980 179.2 53
Aflatoxin B1 aldehyde reductase member 2 AKR7A2 Tbio Enzyme -2.54957 354.9 158
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase DHDH Tbio Enzyme -2.59429 386.0 79
Sucrase-isomaltase, intestinal SI Tchem Enzyme -1.83971 67.3 52
Lactosylceramide alpha-2,3-sialyltransferase ST3GAL5 Tbio Enzyme -1.79569 62.9 97
Hyaluronidase-1 HYAL1 Tbio Enzyme -1.85417 78.6 191
Acid trehalase-like protein 1 PGGHG Tdark Enzyme 0.48 0.88 12
Ubiquitin-conjugating enzyme E2 variant 3 UEVLD Tdark Non-IDG 0.07 0.85 86
NADP-dependent malic enzyme ME1 Tchem Non-IDG -1.97310 90.3 172
Beta-klotho KLB Tbio Enzyme -1.95818 69.9 47