Development Level

Tbio 34 | 11,445
Tdark 4 | 6,588
Tchem 2 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal optic disc morphology 1 | 10
abnormal response to tactile s... 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
decreased IgG1 level 1 | 8
decreased body weight 1 | 161
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
limb grasping 1 | 41
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 30 | 11,493
osteosarcoma 18 | 7,950
ovarian cancer 18 | 8,520
medulloblastoma, large-cell 16 | 6,241
ependymoma 15 | 4,679
invasive ductal carcinoma 15 | 2,951
psoriasis 15 | 6,694
Cancer 12 | 2,499
Cataract 11 | 297
Microphthalmos 11 | 100
glioblastoma 11 | 5,792
Autosomal recessive predisposition 10 | 1,442
Breast cancer 10 | 3,578
Intellectual disability 10 | 1,016
Lens Opacities 10 | 231
Abnormally small eyeball 9 | 97
Decreased size of eyeball 9 | 97
Microphthalmia 9 | 76
interstitial cystitis 9 | 2,312
lung cancer 9 | 4,740
pancreatic cancer 9 | 2,398
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
atypical teratoid / rhabdoid tumor 8 | 5,112
ductal carcinoma in situ 8 | 1,745
malignant mesothelioma 8 | 3,232
pituitary cancer 8 | 1,972
tuberculosis 8 | 2,010
Coloboma 7 | 51
Corneal diameter decreased 7 | 47
Hypoplastic mandible condyle 7 | 275
Mandibular hypoplasia 7 | 275
Microcornea 7 | 47
Micrognathism 7 | 275
Myopia 7 | 176
Orbital separation excessive 7 | 244
Small head 7 | 374
group 3 medulloblastoma 7 | 4,104
group 4 medulloblastoma 7 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
non-small cell lung cancer 7 | 2,890
Aplasia/Hypoplasia of the iris 6 | 10
Astrocytoma, Pilocytic 6 | 3,081
Cleft Palate 6 | 271
Cognitive delay 6 | 608
Craniofacial Abnormalities 6 | 151
Cryptorchidism 6 | 296
Global developmental delay 6 | 608
Hypertensive disease 6 | 292
Kidney cancer 6 | 2,613
Mental and motor retardation 6 | 608
Muscle hypotonia 6 | 571
Short stature 6 | 531
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
nasopharyngeal carcinoma 6 | 1,058
ulcerative colitis 6 | 1,819
Blepharoptosis 5 | 231
Decreased projection of midface 5 | 105
Hepatomegaly 5 | 285
Hypotrophic midface 5 | 105
Joubert syndrome 5 | 66
Low Vision 5 | 174
Low-set, posteriorly rotated ears 5 | 110
Meckel-Gruber syndrome 5 | 13
Midface retrusion 5 | 105
Nystagmus 5 | 317
Patent ductus arteriosus 5 | 90
Small midface 5 | 105
Visual Impairment 5 | 174
active Crohn's disease 5 | 922
adult high grade glioma 5 | 3,801
astrocytoma 5 | 1,146
breast carcinoma 5 | 1,638
chronic rhinosinusitis 5 | 512
gastric carcinoma 5 | 807
juvenile dermatomyositis 5 | 1,187
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074
Chubby cheeks 4 | 50
Depressed nasal ridge 4 | 51
Feeding difficulties in infancy 4 | 175
Full cheeks 4 | 50
Hyperplasia of cheeks 4 | 50
Hypertrophy of cheeks 4 | 50
Increase in blood pressure 4 | 119
Lobar Holoprosencephaly 4 | 20
Maternal oligohydramnios 4 | 31
Multicystic Dysplastic Kidney 4 | 52
Oligohydramnios 4 | 52
Puffy cheeks 4 | 50
Rheumatoid arthritis 4 | 1,191
Sclerocornea 4 | 29
Ulnar polydactyly of fingers 4 | 47
Uranostaphyloschisis 4 | 167
astrocytic glioma 4 | 2,597
lung carcinoma 4 | 2,843

Tissue

Endocrine System 40 | 18,159
Male tissues 40 | 17,142
Digestive Tract 38 | 17,369
Nervous System 38 | 16,725
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Female tissues 37 | 17,400
Liver and Pancreas 36 | 16,750
Blood and immune system 34 | 16,909
Respiratory system 34 | 16,393
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 20 | 12,091
Transcription Factor 13 | 1,400
Enzyme 6 | 4,145
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

camera-type eye development 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein Shroom2 SHROOM2 Tbio Non-IDG -1.07032 11.9 112
Forkhead box protein C2 FOXC2 Tbio Transcription Factor -2.23435 187.0 419
WD repeat-containing and planar cell polarity effector protein fritz homolog WDPCP Tbio Non-IDG -0.84019 7.08 68
Retinal homeobox protein Rx RAX Tbio Transcription Factor -0.52554 4.68 205
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.61316 3.72 43
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
Heat shock factor protein 4 HSF4 Tbio Transcription Factor -2.82845 672.2 263
Receptor for retinol uptake STRA6 STRA6 Tbio Non-IDG -1.78205 67.9 157
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
Cyclin-dependent kinase inhibitor 1C CDKN1C Tbio Enzyme -2.81199 631.0 665