Development Level

Tbio 11 | 11,445
Tchem 7 | 1,598
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 2 | 979
embryonic lethality prior to t... 1 | 278
increased circulating bilirubi... 1 | 16
increased startle reflex 1 | 112

Disease

Carcinoma 12 | 11,493
glioblastoma 10 | 5,792
ovarian cancer 9 | 8,520
Breast cancer 8 | 3,578
Kidney cancer 8 | 2,613
ependymoma 8 | 4,679
medulloblastoma, large-cell 8 | 6,241
adult high grade glioma 7 | 3,801
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
malignant mesothelioma 7 | 3,232
osteosarcoma 7 | 7,950
cystic fibrosis 6 | 1,696
interstitial cystitis 6 | 2,312
lung cancer 6 | 4,740
pancreatic cancer 6 | 2,398
Heart disease 5 | 306
astrocytic glioma 5 | 2,597
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
Astrocytoma, Pilocytic 4 | 3,081
Bipolar Disorder 4 | 666
Cancer 4 | 2,499
Inflammatory bowel disease 4 | 151
Myocardial Ischemia 4 | 169
Rheumatoid arthritis 4 | 1,191
atypical teratoid / rhabdoid tumor 4 | 5,112
cutaneous lupus erythematosus 4 | 1,057
esophageal adenocarcinoma 4 | 737
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
ulcerative colitis 4 | 1,819
Alzheimer's disease 3 | 658
Asthma 3 | 385
Atherosclerosis 3 | 291
Atopic dermatitis 3 | 952
Cerebrovascular disease 3 | 238
Coronary artery disease 3 | 268
Hypertension 3 | 396
Hypertensive disease 3 | 292
Kidney disease 3 | 430
Liver cancer 3 | 604
Multiple Sclerosis 3 | 540
Peripheral vascular disease 3 | 87
Schizophrenia 3 | 1,160
Vasculitis 3 | 80
chronic rhinosinusitis 3 | 512
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
urothelial carcinoma 3 | 318
Alcohol dependence 2 | 107
Breast Neoplasms 2 | 445
Cocaine-Related Disorders 2 | 92
Colitis, Ulcerative 2 | 59
DOID:2627 2 | 94
Depressive disorder 2 | 409
Dermatitis 2 | 157
Diabetic retinopathy 2 | 56
Endometriosis 2 | 540
Epilepsy 2 | 792
Epilepsy, Temporal Lobe 2 | 23
Hypersensitivity 2 | 63
Hypersensitivity reaction type II disease 2 | 253
Intellectual disability 2 | 1,016
Major Depressive Disorder 2 | 301
Malaria 2 | 160
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Multiple myeloma 2 | 1,332
Renal Cell Carcinoma 2 | 214
Strabismus 2 | 270
Substance abuse 2 | 59
Substance-Related Disorders 2 | 115
Toxic encephalopathy 2 | 141
Unipolar Depression 2 | 250
Uremia 2 | 19
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
facioscapulohumeral dystrophy 2 | 288
gastric carcinoma 2 | 807
head and neck cancer 2 | 271
mucosa-associated lymphoid tissue lymphoma 2 | 484
posterior fossa group A ependymoma 2 | 468
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
Cortical blindness 1 | 16
HUNTINGTON DISEASE-LIKE 1 1 | 2
Jakob-Creutzfeldt disease 1 | 3
Kuru 1 | 7
SPONGIFORM ENCEPHALOPATHY WITH NEUROPSYCHIATRIC FEATURES 1 | 2
progressive myoclonus epilepsy 1 | 12

Tissue

Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Blood and immune system 20 | 16,909
Digestive Tract 20 | 17,369
Urinary Tract 20 | 16,678
Male tissues 19 | 17,142
Cardiovascular System 16 | 15,192

Target Family

Non-IDG 11 | 12,091
GPCR 4 | 408
Enzyme 2 | 4,145
Ion Channel 2 | 344
Kinase 2 | 634

GO Process

calcium-mediated signaling usi... 21 | 21
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
G-protein coupled receptor 143 GPR143 Tbio GPCR -1.72669 53.7 93
Adhesion G protein-coupled receptor L1 ADGRL1 Tbio GPCR -1.81420 60.5 108
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
B-cell receptor-associated protein 31 BCAP31 Tbio Non-IDG -1.70781 57.4 398
Ryanodine receptor 2 RYR2 Tclin Ion Channel -2.92980 851.9 138
Peptidyl-prolyl cis-trans isomerase FKBP1B FKBP1B Tchem Enzyme -2.09568 114.2 84
Vascular endothelial growth factor receptor 2 KDR Tclin Kinase -3.67555 4544.8 2373
Major prion protein PRNP Tchem Non-IDG -3.45326 5611.1 484