Development Level

Tchem 21 | 1,598
Tbio 18 | 11,445
Tclin 9 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

increased total body fat amoun... 4 | 134
preweaning lethality, complete... 4 | 979
abnormal behavior 2 | 298
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal digit morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal retinal blood vessel ... 1 | 26
abnormal sleep behavior 1 | 70
abnormal vocalization 1 | 21
decreased IgG3 level 1 | 1
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased cardiac stroke volum... 1 | 6
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 31
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
increased CD4-positive, alpha ... 1 | 4
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
mydriasis 1 | 6
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
prolonged ST segment 1 | 36

Disease

Carcinoma 31 | 11,493
psoriasis 25 | 6,694
osteosarcoma 22 | 7,950
ovarian cancer 20 | 8,520
glioblastoma 19 | 5,792
lung carcinoma 19 | 2,843
Cancer 18 | 2,499
adult high grade glioma 18 | 3,801
lung cancer 18 | 4,740
Astrocytoma, Pilocytic 17 | 3,081
medulloblastoma, large-cell 17 | 6,241
ependymoma 16 | 4,679
malignant mesothelioma 16 | 3,232
atypical teratoid / rhabdoid tumor 15 | 5,112
invasive ductal carcinoma 15 | 2,951
ulcerative colitis 15 | 1,819
non-small cell lung cancer 13 | 2,890
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
tuberculosis 12 | 2,010
astrocytic glioma 11 | 2,597
oligodendroglioma 11 | 2,850
primitive neuroectodermal tumor 11 | 3,035
Pick disease 10 | 1,894
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung adenocarcinoma 10 | 2,716
subependymal giant cell astrocytoma 10 | 2,287
Heart disease 9 | 306
Rheumatoid arthritis 9 | 1,191
diabetes mellitus 9 | 1,728
Breast cancer 8 | 3,578
Multiple Sclerosis 8 | 540
Obesity 8 | 678
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
cystic fibrosis 8 | 1,696
ductal carcinoma in situ 8 | 1,745
pancreatic cancer 8 | 2,398
Arthritis 7 | 290
Asthma 7 | 385
Autosomal recessive predisposition 7 | 1,442
Down syndrome 7 | 499
Hypertension 7 | 396
Schizophrenia 7 | 1,160
cutaneous lupus erythematosus 7 | 1,057
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
pituitary cancer 7 | 1,972
Atherosclerosis 6 | 291
Bipolar Disorder 6 | 666
Kidney cancer 6 | 2,613
Kidney disease 6 | 430
Lung disease 6 | 142
group 4 medulloblastoma 6 | 1,855
Cerebrovascular disease 5 | 238
Heart failure 5 | 162
Hypersensitivity reaction type II disease 5 | 253
Liver cancer 5 | 604
Malaria 5 | 160
Myocardial Ischemia 5 | 169
primary Sjogren syndrome 5 | 735
sarcoidosis 5 | 370
Atopic dermatitis 4 | 952
Breast Neoplasms 4 | 445
Cerebrovascular accident 4 | 63
Coronary artery disease 4 | 268
Dementia 4 | 175
Human immunodeficiency virus infectious disease 4 | 138
Hypertension, Pulmonary 4 | 37
Inflammation 4 | 120
Mammary Neoplasms 4 | 425
Pulmonary Fibrosis 4 | 106
Pulmonary hypertension 4 | 85
Reperfusion Injury 4 | 86
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
hepatocellular carcinoma 4 | 547
mucosa-associated lymphoid tissue lymphoma 4 | 484
periodontitis 4 | 293
Alzheimer's disease 3 | 658
Brain Ischemia 3 | 110
Dermatitis 3 | 157
Dermatitis, Atopic 3 | 37
Endometriosis 3 | 540
Essential Hypertension 3 | 94
Hypereosinophilic syndrome 3 | 71
Infantile onset 3 | 238
Inflammatory bowel disease 3 | 151
Major Depressive Disorder 3 | 301
Peritonitis 3 | 43
Vascular disease 3 | 319
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
head and neck cancer 3 | 271
nephrosclerosis 3 | 333
non diabetic and post-ischemic heart failure 3 | 200
pediatric high grade glioma 3 | 1,064
progressive supranuclear palsy 3 | 676

Tissue

Digestive Tract 49 | 17,369
Endocrine System 48 | 18,159
Female tissues 48 | 17,400
Urinary Tract 48 | 16,678
Liver and Pancreas 47 | 16,750
Male tissues 47 | 17,142
Respiratory system 46 | 16,393
Skin and soft tissues 46 | 17,230
Blood and immune system 45 | 16,909
Nervous System 45 | 16,725
Cardiovascular System 43 | 15,192

Target Family

Non-IDG 18 | 12,091
GPCR 14 | 408
Kinase 7 | 634
Enzyme 5 | 4,145
Ion Channel 4 | 344
Transcription Factor 1 | 1,400

GO Process

calcium-mediated signaling 49 | 49
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prostaglandin D2 receptor 2 PTGDR2 Tchem GPCR -2.38441 265.9 439
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Linker for activation of T-cells family member 1 LAT Tbio Non-IDG -2.16291 169.4 667
Multiple C2 and transmembrane domain-containing protein 2 MCTP2 Tbio Non-IDG -0.74329 5.66 99
Multiple C2 and transmembrane domain-containing protein 1 MCTP1 Tdark Non-IDG -0.49248 3.44 49
Trem-like transcript 1 protein TREML1 Tbio Non-IDG -1.20660 15.8 198
Kinase suppressor of Ras 2 KSR2 Tbio Kinase -0.90433 8.77 280
Calcium uniporter protein, mitochondrial MCU Tbio Ion Channel -2.67075 458.1 25
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.41628 245.1 733
Calcium/calmodulin-dependent protein kinase kinase 2 CAMKK2 Tchem Kinase -2.09841 125.5 257