Development Level

Tbio 26 | 11,445
Tchem 26 | 1,598
Tclin 16 | 613
Tdark 5 | 6,588

Collection

Ion Channel: IDG Consortium (T... 5 | 99

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased lymphocyte cell numb... 3 | 83
embryonic lethality prior to t... 3 | 278
increased startle reflex 3 | 112
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
decreased body weight 2 | 161
decreased circulating amylase ... 2 | 28
decreased circulating glucose ... 2 | 126
decreased circulating magnesiu... 2 | 13
decreased grip strength 2 | 116
enlarged heart 2 | 210
increased monocyte cell number 2 | 63
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal cranium morphology 1 | 36
abnormal eye size 1 | 7
abnormal facial morphology 1 | 17
abnormal femur morphology 1 | 14
abnormal fibula morphology 1 | 2
abnormal forelimb morphology 1 | 2
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal locomotor activation 1 | 16
abnormal pelvic girdle bone mo... 1 | 12
abnormal placenta vasculature 1 | 2
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 10
abnormal rib morphology 1 | 10
abnormal scapula morphology 1 | 3
abnormal spine curvature 1 | 9
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
absent mammary gland 1 | 1
corneal vascularization 1 | 6
cyanosis 1 | 7
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased skeletal muscle mass 1 | 1
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
limb grasping 1 | 41
male infertility 1 | 123
mammalian phenotype 1 | 17
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
respiratory system phenotype 1 | 2
short tibia 1 | 97
small epididymis 1 | 3
small heart 1 | 10
small kidney 1 | 16
small ovary 1 | 1
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small uterus 1 | 3
thin skin 1 | 2

Disease

Carcinoma 53 | 11,493
medulloblastoma, large-cell 36 | 6,241
glioblastoma 35 | 5,792
adult high grade glioma 34 | 3,801
ovarian cancer 34 | 8,520
psoriasis 33 | 6,694
atypical teratoid / rhabdoid tumor 31 | 5,112
osteosarcoma 31 | 7,950
ependymoma 30 | 4,679
lung cancer 27 | 4,740
Kidney cancer 25 | 2,613
primitive neuroectodermal tumor 24 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
lung carcinoma 23 | 2,843
Astrocytoma, Pilocytic 22 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Breast cancer 20 | 3,578
group 3 medulloblastoma 20 | 4,104
invasive ductal carcinoma 20 | 2,951
interstitial cystitis 18 | 2,312
lung adenocarcinoma 18 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
malignant mesothelioma 16 | 3,232
Cancer 15 | 2,499
Hypertension 15 | 396
oligodendroglioma 15 | 2,850
Pick disease 14 | 1,894
non-small cell lung cancer 14 | 2,890
subependymal giant cell astrocytoma 14 | 2,287
Schizophrenia 13 | 1,160
tuberculosis 13 | 2,010
ulcerative colitis 13 | 1,819
Bipolar Disorder 12 | 666
astrocytic glioma 12 | 2,597
colon cancer 12 | 1,478
pancreatic cancer 11 | 2,398
group 4 medulloblastoma 10 | 1,855
Autosomal recessive predisposition 9 | 1,442
Melanoma 9 | 711
ductal carcinoma in situ 9 | 1,745
Asthma 8 | 385
Endometrial cancer 8 | 311
Liver Cirrhosis, Experimental 8 | 769
cystic fibrosis 8 | 1,696
diabetes mellitus 8 | 1,728
pituitary cancer 8 | 1,972
Hypertensive disease 7 | 292
Obesity 7 | 678
Skin cancer 7 | 469
adrenocortical carcinoma 7 | 1,428
breast carcinoma 7 | 1,638
cutaneous lupus erythematosus 7 | 1,057
Alzheimer's disease 6 | 658
Arthritis 6 | 290
Epilepsy 6 | 792
Liver cancer 6 | 604
Malignant hyperthermia 6 | 26
Multiple Sclerosis 6 | 540
aldosterone-producing adenoma 6 | 665
dermatomyositis 6 | 966
juvenile dermatomyositis 6 | 1,187
nasopharyngeal carcinoma 6 | 1,058
primary Sjogren syndrome 6 | 735
primary pancreatic ductal adenocarcinoma 6 | 1,109
Alcoholic Intoxication, Chronic 5 | 289
Atherosclerosis 5 | 291
Intellectual disability 5 | 1,016
Kidney disease 5 | 430
Myopathy 5 | 185
Neurodegenerative disease 5 | 414
Prostatic Neoplasms 5 | 495
Rheumatoid arthritis 5 | 1,191
Waldenstrons macroglobulinemia 5 | 765
active ulcerative colitis 5 | 764
fibroadenoma 5 | 559
sarcoidosis 5 | 370
Atopic dermatitis 4 | 952
Autistic Disorder 4 | 364
Dementia 4 | 175
Endometriosis 4 | 540
Heart disease 4 | 306
Hypersensitivity reaction type II disease 4 | 253
Hypervitaminosis D 4 | 8
Lung disease 4 | 142
Malaria 4 | 160
Migraine 4 | 83
Muscle hypotonia 4 | 571
Postmenopausal osteoporosis 4 | 19
Rickets 4 | 49
Seizures 4 | 596
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
medulloblastoma 4 | 720
periodontitis 4 | 293
posterior fossa group A ependymoma 4 | 468
progressive supranuclear palsy 4 | 676
Allergic hypersensitivity disease 3 | 126
Down syndrome 3 | 499
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic rhinosinusitis 3 | 512

Tissue

Endocrine System 72 | 18,159
Digestive Tract 69 | 17,369
Nervous System 69 | 16,725
Female tissues 68 | 17,400
Liver and Pancreas 67 | 16,750
Skin and soft tissues 67 | 17,230
Urinary Tract 67 | 16,678
Male tissues 66 | 17,142
Blood and immune system 65 | 16,909
Respiratory system 63 | 16,393
Cardiovascular System 58 | 15,192

Target Family

Ion Channel 31 | 344
Non-IDG 20 | 12,091
GPCR 6 | 408
Transporter 6 | 473
Enzyme 5 | 4,145
Kinase 4 | 634
Nuclear Receptor 1 | 48

GO Process

calcium ion transport 73 | 73
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pro-neuropeptide Y NPY Tbio Non-IDG -3.83401 7433.3 432
Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 Tclin Ion Channel -3.62589 4263.7 202
C-C chemokine receptor type 5 CCR5 Tclin GPCR -3.59886 4115.5 1202
Vitamin D3 receptor VDR Tclin Nuclear Receptor -3.62166 3805.7 575