Development Level

Tclin 5 | 612
Tchem 1 | 1,885

Disease

Carcinoma 6 | 11,192
Atrial Fibrillation 5 | 120
Chronic heart failure 5 | 44
Myocardial Perfusion Imaging Adjunct 5 | 25
Platelet Aggregation Inhibition 5 | 22
Prevention of Cerebral Thrombosis 5 | 29
Breast cancer 4 | 3,469
atypical teratoid / rhabdoid tumor 4 | 4,971
invasive ductal carcinoma 4 | 2,867
malignant mesothelioma 4 | 3,135
medulloblastoma, large-cell 4 | 6,086
oligodendroglioma 4 | 2,768
ovarian cancer 4 | 8,297
Astrocytoma, Pilocytic 3 | 3,006
Pick disease 3 | 1,856
adult high grade glioma 3 | 3,701
astrocytic glioma 3 | 2,530
breast carcinoma 3 | 1,589
colon cancer 3 | 1,428
ependymoma 3 | 4,559
lung cancer 3 | 4,607
osteosarcoma 3 | 7,766
Bipolar Disorder 2 | 646
Impotence 2 | 44
glioblastoma 2 | 5,635
group 4 medulloblastoma 2 | 1,806
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,204
lung adenocarcinoma 2 | 2,627
medulloblastoma 2 | 702
non-small cell lung cancer 2 | 2,799
primitive neuroectodermal tumor 2 | 2,957
subependymal giant cell astrocytoma 2 | 2,230
Acquired metabolic disease 1 | 329
Alcoholic Intoxication, Chronic 1 | 283
Anterior ischemic optic neuropathy 1 | 3
Asthma 1 | 370
Autosomal recessive nonsyndromic deafness 8 1 | 5
Benign prostatic hyperplasia 1 | 7
Brain cancer 1 | 30
Breast Neoplasms 1 | 423
Choreatic disease 1 | 51
Conduct disorder 1 | 32
Coronary artery disease 1 | 253
Cystic kidney disease 1 | 25
DYSKINESIA, LIMB AND OROFACIAL, INFANTILE-ONSET 1 | 1
Depressive disorder 1 | 401
Dyspepsia 1 | 32
Heart disease 1 | 288
Huntington's disease 1 | 75
Hypertension 1 | 372
Hypoactive sexual desire disorder 1 | 8
Hypogonadism 1 | 169
Kidney cancer 1 | 2,548
Learning Disorders 1 | 27
Major Depressive Disorder 1 | 293
Mammary Neoplasms 1 | 403
Mental Depression 1 | 325
Multiple Sclerosis 1 | 527
Multiple system atrophy 1 | 28
Neoplasm Metastasis 1 | 160
Nonorganic psychosis 1 | 83
Parkinson's disease 1 | 378
Peripheral vascular disease 1 | 81
Peyronie's disease 1 | 9
Premature ejaculation 1 | 16
Priapism 1 | 5
Prostatic hypertrophy 1 | 8
Psychotic Disorders 1 | 150
Pulmonary hypertension 1 | 85
Rheumatoid arthritis 1 | 1,156
STRIATAL DEGENERATION, AUTOSOMAL DOMINANT 2 1 | 1
Schizophrenia 1 | 1,136
Stuttering 1 | 17
X-linked cerebral adrenoleukodystrophy 1 | 114
cutaneous lupus erythematosus 1 | 1,016
diabetes mellitus 1 | 1,683
ductal carcinoma in situ 1 | 1,686
fibroadenoma 1 | 538
gastric cancer 1 | 445
group 3 medulloblastoma 1 | 4,002
head and neck cancer 1 | 263
interstitial cystitis 1 | 2,237
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,902
lung carcinoma 1 | 2,755
mucosa-associated lymphoid tissue lymphoma 1 | 473
non-inflammatory breast cancer 1 | 63
pancreatic cancer 1 | 2,322
pancreatic carcinoma 1 | 555
pituitary cancer 1 | 1,915
posterior fossa group A ependymoma 1 | 456
primary Sjogren syndrome 1 | 710
progressive supranuclear palsy 1 | 656
psoriasis 1 | 6,514
pulmonary arterial hypertension 1 | 76
tuberculosis 1 | 1,963
type II diabetes mellitus and post-ischemic heart failure 1 | 85
ulcerative colitis 1 | 1,765

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Enzyme 6 | 4,145

GO Process

cGMP catabolic process 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

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