Development Level

Tbio 14 | 11,445
Tchem 6 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased lean body mass 2 | 135
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal nail morphology 1 | 8
abnormal optic disc morphology 1 | 10
abnormal pancreas morphology 1 | 13
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal vertebrae morphology 1 | 18
cataract 1 | 92
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
fused cornea and lens 1 | 5
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
iris synechia 1 | 3
limb grasping 1 | 41
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
small superior vagus ganglion 1 | 74

Disease

Carcinoma 18 | 11,493
osteosarcoma 16 | 7,950
Cancer 15 | 2,499
glioblastoma 14 | 5,792
lung cancer 14 | 4,740
ovarian cancer 12 | 8,520
atypical teratoid / rhabdoid tumor 11 | 5,112
psoriasis 11 | 6,694
ependymoma 10 | 4,679
lung carcinoma 10 | 2,843
malignant mesothelioma 9 | 3,232
pancreatic cancer 9 | 2,398
primitive neuroectodermal tumor 9 | 3,035
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung adenocarcinoma 8 | 2,716
medulloblastoma, large-cell 8 | 6,241
Prostatic Neoplasms 7 | 495
cystic fibrosis 7 | 1,696
group 4 medulloblastoma 7 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
Breast Neoplasms 6 | 445
Breast cancer 6 | 3,578
Kidney disease 6 | 430
Mammary Neoplasms 6 | 425
Short stature 6 | 531
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
oligodendroglioma 6 | 2,850
primary pancreatic ductal adenocarcinoma 6 | 1,109
Abnormally small eyeball 5 | 97
Astrocytoma, Pilocytic 5 | 3,081
Cleft Lip 5 | 141
Cleft Palate 5 | 271
Cognitive delay 5 | 608
Decreased size of eyeball 5 | 97
Global developmental delay 5 | 608
Kidney cancer 5 | 2,613
Mental and motor retardation 5 | 608
Microphthalmos 5 | 100
astrocytic glioma 5 | 2,597
Adenocarcinoma 4 | 122
Carcinoma, Hepatocellular 4 | 228
Cataract 4 | 297
Cell Transformation, Neoplastic 4 | 97
Hydrocephalus 4 | 152
Liver carcinoma 4 | 240
Muscle hypotonia 4 | 571
Neoplastic Cell Transformation 4 | 89
Osteoarthritis 4 | 184
Osteoporosis 4 | 363
Polydactyly 4 | 107
Schizophrenia 4 | 1,160
Small head 4 | 374
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
hepatocellular carcinoma 4 | 547
interstitial cystitis 4 | 2,312
interstitial lung disease 4 | 298
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Cardiovascular system disease 3 | 246
Depressive disorder 3 | 409
Dull intelligence 3 | 645
Endometriosis 3 | 540
Epilepsy 3 | 792
Gout 3 | 106
Heart disease 3 | 306
Holoprosencephaly 3 | 56
Hypertension 3 | 396
Hypoplastic mandible condyle 3 | 275
Lens Opacities 3 | 231
Liver Cirrhosis, Experimental 3 | 769
Lobar Holoprosencephaly 3 | 20
Low intelligence 3 | 645
Major Depressive Disorder 3 | 301
Mandibular hypoplasia 3 | 275
Mental deficiency 3 | 645
Neoplasm Invasiveness 3 | 161
Neoplasm Metastasis 3 | 168
Orbital separation diminished 3 | 23
Poor school performance 3 | 645
Prostate cancer 3 | 175
Proteinuria 3 | 144
Seizures 3 | 596
Skin cancer 3 | 469
Splenomegaly 3 | 190
Type 2 diabetes mellitus 3 | 272
Ulnar polydactyly of fingers 3 | 47
Vascular disease 3 | 319
astrocytoma 3 | 1,146
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
pediatric high grade glioma 3 | 1,064

Tissue

Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Blood and immune system 21 | 16,909
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 13 | 12,091
Transcription Factor 4 | 1,400
Enzyme 2 | 4,145
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

branching morphogenesis of an ... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Protein timeless homolog TIMELESS Tbio Non-IDG -2.76871 578.0 138
Polycystin-1 PKD1 Tbio Non-IDG -2.60276 379.9 123
Growth/differentiation factor 7 GDF7 Tbio Non-IDG -1.56725 40.0 180
Hepatocyte growth factor receptor MET Tclin Kinase -3.32232 2013.7 1982
Hepatocyte nuclear factor 1-beta HNF1B Tbio Transcription Factor -2.63510 401.5 403
Ras-interacting protein 1 RASIP1 Tbio Non-IDG -1.32949 18.7 77
Extracellular calcium-sensing receptor CASR Tclin GPCR -3.22181 1714.9 441