Development Level

Tbio 34 | 11,445
Tchem 6 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal startle reflex 1 | 15
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased lean body mass 1 | 135
edema 1 | 59
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased bone mineral density 1 | 72
mammalian phenotype 1 | 17
thrombocytosis 1 | 27

Disease

Carcinoma 28 | 11,493
ovarian cancer 25 | 8,520
Cancer 24 | 2,499
osteosarcoma 22 | 7,950
psoriasis 21 | 6,694
Breast cancer 20 | 3,578
malignant mesothelioma 18 | 3,232
lung cancer 17 | 4,740
glioblastoma 16 | 5,792
Cleft Palate 14 | 271
ependymoma 14 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
group 3 medulloblastoma 13 | 4,104
Short stature 12 | 531
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
medulloblastoma, large-cell 12 | 6,241
non-small cell lung cancer 12 | 2,890
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
lung carcinoma 11 | 2,843
Intellectual disability 10 | 1,016
atypical teratoid / rhabdoid tumor 10 | 5,112
breast carcinoma 10 | 1,638
cystic fibrosis 10 | 1,696
Cleft Lip 9 | 141
Cryptorchidism 9 | 296
Dull intelligence 9 | 645
Kidney cancer 9 | 2,613
Kidney disease 9 | 430
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Orbital separation excessive 9 | 244
Poor school performance 9 | 645
oligodendroglioma 9 | 2,850
pancreatic cancer 9 | 2,398
primitive neuroectodermal tumor 9 | 3,035
Adenoma 8 | 167
Astrocytoma, Pilocytic 8 | 3,081
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
adult high grade glioma 8 | 3,801
interstitial cystitis 8 | 2,312
Craniofacial Abnormalities 7 | 151
Muscle hypotonia 7 | 571
Osteoporosis 7 | 363
Polydactyly 7 | 107
Stomach Neoplasms 7 | 300
adrenocortical carcinoma 7 | 1,428
astrocytic glioma 7 | 2,597
ductal carcinoma in situ 7 | 1,745
group 4 medulloblastoma 7 | 1,855
pituitary cancer 7 | 1,972
Alzheimer's disease 6 | 658
Breast Neoplasms 6 | 445
Colorectal Neoplasms 6 | 243
Congenital deafness 6 | 185
Deafness 6 | 198
Down syndrome 6 | 499
Epilepsy 6 | 792
Hearing Loss, Partial 6 | 185
Highly variable severity 6 | 157
Low set ears 6 | 181
Mammary Neoplasms 6 | 425
Penile hypospadias 6 | 106
Renal agenesis 6 | 29
Seizures 6 | 596
Variable expressivity 6 | 157
colon cancer 6 | 1,478
hearing impairment 6 | 199
nasopharyngeal carcinoma 6 | 1,058
pediatric high grade glioma 6 | 1,064
subependymal giant cell astrocytoma 6 | 2,287
Abnormally small eyeball 5 | 97
Absent auditory canals 5 | 23
Absent external auditory canals 5 | 23
Acquired scoliosis 5 | 281
Atretic auditory canal 5 | 23
Autosomal recessive predisposition 5 | 1,442
Bilateral fifth finger clinodactyly 5 | 110
Congenital Epicanthus 5 | 177
Congenital small ears 5 | 48
Curvature of little finger 5 | 110
Curvature of spine 5 | 282
Decreased size of eyeball 5 | 97
Liver Cirrhosis, Experimental 5 | 769
Liver cancer 5 | 604
Pancreatic Neoplasm 5 | 85
Pancreatic Neoplasms 5 | 85
Parkinson's disease 5 | 392
Pick disease 5 | 1,894
Prostatic Neoplasms 5 | 495
Schizophrenia 5 | 1,160
Small head 5 | 374
Uranostaphyloschisis 5 | 167
Vascular disease 5 | 319
cutaneous lupus erythematosus 5 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962

Tissue

Female tissues 41 | 17,400
Urinary Tract 41 | 16,678
Digestive Tract 40 | 17,369
Endocrine System 40 | 18,159
Male tissues 39 | 17,142
Skin and soft tissues 38 | 17,230
Nervous System 37 | 16,725
Blood and immune system 36 | 16,909
Liver and Pancreas 36 | 16,750
Respiratory system 35 | 16,393
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 24 | 12,091
Transcription Factor 15 | 1,400
Enzyme 1 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

branching involved in ureteric... 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein Wnt-6 WNT6 Tbio Non-IDG -1.65830 46.6 186
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
GDNF-inducible zinc finger protein 1 GZF1 Tbio Transcription Factor -0.34461 3.36 48
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Transcription factor 21 TCF21 Tbio Transcription Factor -1.80598 67.7 120
Paired box protein Pax-8 PAX8 Tbio Transcription Factor -2.64765 442.1 540
Homeobox protein Hox-D11 HOXD11 Tbio Transcription Factor -1.59090 36.3 251
Gremlin-1 GREM1 Tbio Non-IDG -2.91296 826.9 397
Homeobox protein Hox-A11 HOXA11 Tbio Transcription Factor -1.96653 87.2 270