Development Level

Tbio 6 | 11,445
Tclin 3 | 613
Tchem 2 | 1,598

IMPC Phenotype

embryonic lethality prior to t... 3 | 278
preweaning lethality, complete... 3 | 979
impaired glucose tolerance 2 | 75
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
absent startle reflex 1 | 24
decreased body weight 1 | 161
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41

Disease

Carcinoma 9 | 11,493
Cancer 8 | 2,499
lung cancer 7 | 4,740
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
non-small cell lung cancer 6 | 2,890
ovarian cancer 6 | 8,520
Breast cancer 5 | 3,578
Cleft Lip 5 | 141
Cleft Palate 5 | 271
Kidney cancer 5 | 2,613
Schizophrenia 5 | 1,160
invasive ductal carcinoma 5 | 2,951
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Choanal Atresia 4 | 42
Cognitive delay 4 | 608
Depressive disorder 4 | 409
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Hypospadias 4 | 53
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mammary Neoplasms 4 | 425
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Osteoporosis 4 | 363
Poor school performance 4 | 645
Seizures 4 | 596
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Abnormally small eyeball 3 | 97
Astrocytoma, Pilocytic 3 | 3,081
Craniofacial Abnormalities 3 | 151
Cryptorchidism 3 | 296
Decreased projection of midface 3 | 105
Decreased size of eyeball 3 | 97
Epilepsy 3 | 792
Generalized osteopenia 3 | 99
Highly variable severity 3 | 157
Holoprosencephaly 3 | 56
Hydrocephalus 3 | 152
Hydronephrosis 3 | 89
Hypertensive disease 3 | 292
Hypotrophic malar bone 3 | 129
Hypotrophic midface 3 | 105
Liver Cirrhosis 3 | 181
Lobar Holoprosencephaly 3 | 20
Lung Neoplasms 3 | 232
Major Depressive Disorder 3 | 301
Malar flattening 3 | 129
Mental Depression 3 | 333
Microphthalmos 3 | 100
Midface retrusion 3 | 105
Osteopenia 3 | 99
Parkinson's disease 3 | 392
Prostatic Neoplasms 3 | 495
Pulmonary Fibrosis 3 | 106
Renal Cell Carcinoma 3 | 214
Short stature 3 | 531
Small midface 3 | 105
Stomach Neoplasms 3 | 300
Strabismus 3 | 270
Syndactyly of fingers 3 | 48
Syndactyly of the toes 3 | 45
Unipolar Depression 3 | 250
Variable expressivity 3 | 157
cutaneous lupus erythematosus 3 | 1,057
group 3 medulloblastoma 3 | 4,104
lung adenocarcinoma 3 | 2,716
spina bifida 3 | 1,074
Broad thumbs 2 | 28
Carcinoma, Renal Cell 2 | 124
Carcinoma, Squamous Cell 2 | 110
Coronal craniosynostosis 2 | 14
Decreased projection of maxilla 2 | 66
Deficiency of upper jaw bones 2 | 66
Esophageal atresia 2 | 43
Hypodontia 2 | 81
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Hypoplasia of the maxilla 2 | 66
Hypoplastic feet 2 | 66
Hypotrophic maxilla 2 | 66
Inadequate arch length for tooth size 2 | 45
Maxillary retrognathia 2 | 66
Retrusion of upper jaw bones 2 | 66
Small testicle 2 | 75
Tooth Crowding 2 | 45
Tooth mass arch size discrepancy 2 | 45
Tooth size discrepancy 2 | 45
inflammatory breast cancer 2 | 286

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192

Target Family

Non-IDG 7 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634

GO Process

branching involved in salivary... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.13063 1294.7 1785
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Epithelial splicing regulatory protein 2 ESRP2 Tbio Non-IDG -1.03680 8.36 132
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Laminin subunit alpha-5 LAMA5 Tbio Non-IDG -1.43472 26.4 217
Fibroblast growth factor receptor 2 FGFR2 Tclin Kinase -3.08664 1210.6 948
Sonic hedgehog protein SHH Tchem Non-IDG -3.44287 2879.1 383
Protein-glutamine gamma-glutamyltransferase 2 TGM2 Tchem Enzyme -3.22049 1602.3 843
Fibroblast growth factor 8 FGF8 Tbio Non-IDG -2.73368 532.0 299
Fibroblast growth factor 7 FGF7 Tbio Non-IDG -3.16409 1534.1 267