Development Level

Tbio 19 | 11,445
Tchem 8 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
increased startle reflex 3 | 112
abnormal bone mineralization 2 | 38
decreased body weight 2 | 161
decreased lean body mass 2 | 135
increased total body fat amoun... 2 | 134
mammalian phenotype 2 | 17
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal optic disc morphology 1 | 10
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased bone mineral density 1 | 72
increased monocyte cell number 1 | 63
irregularly shaped pupil 1 | 7
kinked tail 1 | 2
limb grasping 1 | 41
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 21 | 11,493
Cancer 18 | 2,499
osteosarcoma 18 | 7,950
ovarian cancer 17 | 8,520
ependymoma 13 | 4,679
psoriasis 13 | 6,694
Breast cancer 12 | 3,578
ulcerative colitis 12 | 1,819
interstitial cystitis 11 | 2,312
invasive ductal carcinoma 11 | 2,951
medulloblastoma, large-cell 11 | 6,241
cystic fibrosis 10 | 1,696
lung adenocarcinoma 10 | 2,716
lung cancer 10 | 4,740
malignant mesothelioma 10 | 3,232
non-small cell lung cancer 10 | 2,890
pancreatic cancer 10 | 2,398
glioblastoma 9 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
atypical teratoid / rhabdoid tumor 8 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Astrocytoma, Pilocytic 7 | 3,081
Craniofacial Abnormalities 7 | 151
Strabismus 7 | 270
breast carcinoma 7 | 1,638
gastric carcinoma 7 | 807
Breast Neoplasms 6 | 445
Cleft Palate 6 | 271
Heart disease 6 | 306
Kidney disease 6 | 430
adult high grade glioma 6 | 3,801
lung carcinoma 6 | 2,843
primary pancreatic ductal adenocarcinoma 6 | 1,109
Autosomal recessive predisposition 5 | 1,442
Hypertension 5 | 396
Mammary Neoplasms 5 | 425
Schizophrenia 5 | 1,160
acute quadriplegic myopathy 5 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
ductal carcinoma in situ 5 | 1,745
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
Adenoma 4 | 167
Brachydactyly 4 | 156
Cerebrovascular disease 4 | 238
Colonic Neoplasms 4 | 142
Congenital Heart Defects 4 | 58
Congenital heart disease 4 | 93
Dull intelligence 4 | 645
Endometriosis 4 | 540
Epilepsy 4 | 792
Erectile dysfunction 4 | 32
Heart Defects, Congenital 4 | 37
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Liver Cirrhosis 4 | 181
Liver Cirrhosis, Experimental 4 | 769
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Muscle hypotonia 4 | 571
Neoplasm Metastasis 4 | 168
Obesity 4 | 678
Poor school performance 4 | 645
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
Vascular disease 4 | 319
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
group 3 medulloblastoma 4 | 4,104
group 4 medulloblastoma 4 | 1,855
juvenile dermatomyositis 4 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primitive neuroectodermal tumor 4 | 3,035
sonic hedgehog group medulloblastoma 4 | 467
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
Acquired scoliosis 3 | 281
Alzheimer's disease 3 | 658
Atherosclerosis 3 | 291
Bilateral fifth finger clinodactyly 3 | 110
Coronary artery disease 3 | 268
Curvature of little finger 3 | 110
Curvature of spine 3 | 282
Depressive disorder 3 | 409
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Glaucoma 3 | 239
Lung disease 3 | 142
Pick disease 3 | 1,894
Type 2 diabetes mellitus 3 | 272
Ventricular Septal Defects 3 | 119
adrenocortical carcinoma 3 | 1,428
limb girdle muscular dystrophy 2A 3 | 213
medulloblastoma 3 | 720
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
urothelial carcinoma 3 | 318

Tissue

Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 27 | 16,750
Urinary Tract 26 | 16,678
Digestive Tract 25 | 17,369
Male tissues 25 | 17,142
Skin and soft tissues 25 | 17,230
Nervous System 24 | 16,725
Respiratory system 24 | 16,393
Cardiovascular System 23 | 15,192
Blood and immune system 22 | 16,909

Target Family

Non-IDG 18 | 12,091
Transcription Factor 7 | 1,400
Kinase 3 | 634
GPCR 1 | 408

GO Process

branching involved in blood ve... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Forkhead box protein C2 FOXC2 Tbio Transcription Factor -2.23435 187.0 419
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Nuclear factor of activated T-cells, cytoplasmic 4 NFATC4 Tbio Transcription Factor -1.93766 88.3 358
Plexin-D1 PLXND1 Tbio Non-IDG -1.64721 46.3 171
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Putative RNA-binding protein 15 RBM15 Tbio Non-IDG -1.84271 68.3 90
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Notch-regulated ankyrin repeat-containing protein NRARP Tbio Non-IDG -1.09051 13.9 99
Indian hedgehog protein IHH Tbio Non-IDG -2.61880 417.4 375