Development Level

Tchem 4 | 1,388
Tbio 1 | 11,651

IMPC Phenotype

abnormal cranium morphology 2 | 36
preweaning lethality, incomple... 2 | 499
abnormal hair texture 1 | 4
abnormal incisor morphology 1 | 4
abnormal maxilla morphology 1 | 17
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased total body fat amoun... 1 | 207
increased circulating amylase ... 1 | 25
increased heart weight 1 | 62

Disease

Carcinoma 4 | 11,493
ovarian cancer 4 | 8,520
lung cancer 3 | 4,740
Alzheimer's disease 2 | 658
Atherosclerosis 2 | 291
Osteoporosis 2 | 363
invasive ductal carcinoma 2 | 2,951
medulloblastoma, large-cell 2 | 6,241
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
subependymal giant cell astrocytoma 2 | 2,287
Abdominal Pain 1 | 98
Abnormal rapid eye movement sleep 1 | 8
Abnormality of metabolism/homeostasis 1 | 134
Abnormality of vision 1 | 40
Acute diarrhea 1 | 2
Alzheimer Disease 1 | 83
Amnesia, Transient Global 1 | 9
Amyloidosis 1 | 67
Amyotrophic lateral sclerosis 1 | 451
Angioedema 1 | 38
Atopic dermatitis 1 | 952
Atrial Septal Defects 1 | 85
Autonomic Nervous System Diseases 1 | 1
Autonomic nervous system disorders 1 | 19
Biliary atresia 1 | 12
Bipolar Disorder 1 | 666
Bulbous nasal tip 1 | 48
Bulbous nose 1 | 48
Candidiasis 1 | 55
Capuchin ears 1 | 17
Carboxypeptidase N Deficiency 1 | 1
Cataplexy 1 | 11
Chlamydia 1 | 21
Congenital Heart Defects 1 | 58
Constipation 1 | 181
Contractures of the interphalangeal joint of the thumb 1 | 1
Craniofacial Abnormalities 1 | 151
Crohn's disease 1 | 321
Cupped ears (finding) 1 | 17
Dementia 1 | 175
Dermatologic disorders 1 | 93
Diabetes Mellitus, Insulin-Dependent 1 | 48
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 1 1 | 43
Diabetes Mellitus, Type 2 1 | 142
Dysautonomia 1 | 20
Dyschezia 1 | 135
Essential Hypertension 1 | 94
Excessive daytime somnolence 1 | 14
Hallucinations 1 | 34
Hallucinations, Sensory 1 | 33
Heart Defects, Congenital 1 | 37
Hirschsprung Disease 1 | 31
Hirschsprung Disease, Cardiac Defects, and Autonomic Dysfunction 1 | 1
Hirschsprung's disease 1 | 46
Hyperinsulinism 1 | 133
Hypertension 1 | 396
Hypothyroidism 1 | 122
Intestinal Obstruction 1 | 31
Kidney cancer 1 | 2,613
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Lymphogranuloma venereum 1 | 11
Megacolon 1 | 29
Narcolepsy 1 | 72
Narcolepsy-Cataplexy Syndrome 1 | 8
Narcolepsy-cataplexy 1 | 21
Nausea and vomiting 1 | 97
Overcurvature of nail 1 | 6
Peroneal nerve paralysis 1 | 11
Peroneal neuropathy 1 | 4
Pick disease 1 | 1,894
Posteriorly rotated ear 1 | 61
Potato nose 1 | 48
Pyelonephritis 1 | 13
Schizophrenia 1 | 1,160
Short nose 1 | 132
Skin Abnormalities 1 | 37
Small nose 1 | 132
Tapering fingers (finding) 1 | 25
Type 1 diabetes mellitus 1 | 109
Type 2 diabetes mellitus 1 | 272
Ventricular Septal Defects 1 | 119
Waldenstrons macroglobulinemia 1 | 765
Weight decreased 1 | 103
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,728
esophageal adenocarcinoma 1 | 737
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung adenocarcinoma 1 | 2,716
lung carcinoma 1 | 2,843
nephrosclerosis 1 | 333
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
posterior fossa group A ependymoma 1 | 468
psoriasis 1 | 6,694
tuberculosis 1 | 2,010

Tissue

Endocrine System 5 | 18,159
Liver and Pancreas 5 | 16,750
Urinary Tract 5 | 16,678
Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Female tissues 4 | 17,400
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230

Target Family

Enzyme 5 | 4,145

GO Process

bradykinin catabolic process 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Carboxypeptidase N catalytic chain CPN1 Tchem Enzyme -2.71738 529.1 145
Insulin-degrading enzyme IDE Tchem Enzyme -2.57779 392.8 331
Pro-cathepsin H CTSH Tchem Enzyme -2.36930 222.0 253
Xaa-Pro aminopeptidase 1 XPNPEP1 Tbio Enzyme -2.46846 296.9 111