Development Level

Tbio 24 | 11,445
Tchem 6 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased body length 3 | 101
abnormal bone structure 2 | 187
abnormal femur morphology 2 | 14
abnormal joint morphology 2 | 23
abnormal radius morphology 2 | 8
abnormal tibia morphology 2 | 14
abnormal ulna morphology 2 | 8
abnormal vertebrae morphology 2 | 18
decreased bone mineral content 2 | 151
decreased circulating calcium ... 2 | 36
decreased circulating glucose ... 2 | 126
decreased circulating phosphat... 2 | 27
decreased grip strength 2 | 116
decreased total body fat amoun... 2 | 207
increased circulating alkaline... 2 | 122
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal clavicle morphology 1 | 6
abnormal coat appearance 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal eyelid fusion 1 | 3
abnormal eyelid morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal fibula morphology 1 | 2
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal rib morphology 1 | 10
abnormal scapula morphology 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
abnormal vertebral arch morpho... 1 | 9
abnormal vibrissa morphology 1 | 25
absent mammary gland 1 | 1
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased skeletal muscle mass 1 | 1
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating bilirubi... 1 | 16
increased circulating potassiu... 1 | 29
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
long tail 1 | 1
mammalian phenotype 1 | 17
microphthalmia 1 | 26
narrow eye opening 1 | 12
polydactyly 1 | 7
protruding tongue 1 | 3
short tibia 1 | 97
small heart 1 | 10
small kidney 1 | 16
small ovary 1 | 1
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small uterus 1 | 3
thick tail 1 | 1
thin skin 1 | 2

Disease

Carcinoma 27 | 11,493
psoriasis 19 | 6,694
glioblastoma 17 | 5,792
ovarian cancer 17 | 8,520
Cancer 16 | 2,499
osteosarcoma 15 | 7,950
medulloblastoma, large-cell 13 | 6,241
Breast cancer 12 | 3,578
adult high grade glioma 12 | 3,801
non-small cell lung cancer 12 | 2,890
atypical teratoid / rhabdoid tumor 11 | 5,112
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
lung cancer 11 | 4,740
Autosomal recessive predisposition 10 | 1,442
Short stature 10 | 531
interstitial cystitis 10 | 2,312
Astrocytoma, Pilocytic 9 | 3,081
breast carcinoma 9 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung carcinoma 9 | 2,843
malignant mesothelioma 9 | 3,232
pancreatic cancer 9 | 2,398
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Intellectual disability 8 | 1,016
Mental and motor retardation 8 | 608
group 3 medulloblastoma 8 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
ulcerative colitis 8 | 1,819
Dull intelligence 7 | 645
Kidney cancer 7 | 2,613
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Orbital separation excessive 7 | 244
Osteoporosis 7 | 363
Poor school performance 7 | 645
adrenocortical carcinoma 7 | 1,428
colon cancer 7 | 1,478
ependymoma 7 | 4,679
Abnormality of the metaphyses 6 | 48
Bilateral fifth finger clinodactyly 6 | 110
Concave bridge of nose 6 | 195
Congenital deafness 6 | 185
Craniosynostosis 6 | 74
Curvature of little finger 6 | 110
Deafness 6 | 198
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Hearing Loss, Partial 6 | 185
Hypoplastic feet 6 | 66
Muscle hypotonia 6 | 571
Stomach Neoplasms 6 | 300
hearing impairment 6 | 199
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
nasopharyngeal carcinoma 6 | 1,058
oligodendroglioma 6 | 2,850
Ankylosis 5 | 28
Anteverted nostril 5 | 191
Big calvaria 5 | 147
Brachydactyly 5 | 156
Breast Neoplasms 5 | 445
Cleft Lip 5 | 141
Cleft Palate 5 | 271
Colorectal Neoplasms 5 | 243
Cryptorchidism 5 | 296
Downward slant of palpebral fissure 5 | 158
Femoral bowing 5 | 20
Frontal bossing 5 | 157
Hypoplastic mandible condyle 5 | 275
Hypotrophic malar bone 5 | 129
Increased head circumference 5 | 147
Increased size of cranium 5 | 147
Increased size of skull 5 | 147
Liver Cirrhosis, Experimental 5 | 769
Malar flattening 5 | 129
Mammary Neoplasms 5 | 425
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Osteoarthritis 5 | 184
Rickets 5 | 49
Short hands 5 | 50
aldosterone-producing adenoma 5 | 665
cutaneous lupus erythematosus 5 | 1,057
ductal carcinoma in situ 5 | 1,745
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,109
primitive neuroectodermal tumor 5 | 3,035
Curvature of spine 4 | 282
Delayed bone age 4 | 136
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
Seizures 4 | 596
Small nose 4 | 132
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
spina bifida 4 | 1,074
tuberculosis 4 | 2,010

Tissue

Digestive Tract 35 | 17,369
Blood and immune system 34 | 16,909
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Respiratory system 34 | 16,393
Male tissues 33 | 17,142
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Nervous System 32 | 16,725
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 8 | 4,145
Kinase 5 | 634
GPCR 2 | 408
Transcription Factor 2 | 1,400

GO Process

bone mineralization 35 | 35
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
Zinc finger and BTB domain-containing protein 40 ZBTB40 Tdark Transcription Factor -0.27108 1.81 127
Ribosome maturation protein SBDS SBDS Tbio Non-IDG -2.24233 174.4 139
Extracellular tyrosine-protein kinase PKDCC PKDCC Tbio Kinase -1.15951 16.2 51
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
Eukaryotic translation initiation factor 2-alpha kinase 3 EIF2AK3 Tchem Kinase -3.05781 896.8 450
Asporin ASPN Tbio Non-IDG -2.64447 408.2 128
Fibroblast growth factor receptor 3 FGFR3 Tclin Kinase -3.00731 1050.1 479
Pleiotrophin PTN Tbio Non-IDG -2.85163 746.7 392