Development Level

Tbio 36 | 11,445
Tclin 5 | 613
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

decreased bone mineral density 8 | 126
abnormal bone structure 7 | 187
decreased body length 7 | 101
decreased body weight 7 | 161
decreased lean body mass 6 | 135
decreased bone mineral content 5 | 151
increased heart weight 5 | 62
preweaning lethality, complete... 5 | 979
increased total body fat amoun... 4 | 134
abnormal bone mineralization 3 | 38
abnormal cranium morphology 3 | 36
abnormal tooth morphology 3 | 24
decreased circulating amylase ... 3 | 28
increased startle reflex 3 | 112
abnormal behavior 2 | 298
abnormal cornea morphology 2 | 31
abnormal eye morphology 2 | 68
abnormal eye pigmentation 2 | 3
abnormal maxilla morphology 2 | 17
abnormal tibia morphology 2 | 14
absent pinna reflex 2 | 23
corneal opacity 2 | 32
corneal vascularization 2 | 6
decreased circulating calcium ... 2 | 36
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased total body fat amoun... 2 | 207
increased circulating HDL chol... 2 | 80
increased circulating phosphat... 2 | 26
increased mean corpuscular vol... 2 | 92
mammalian phenotype 2 | 17
short tibia 2 | 97
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo development 1 | 7
abnormal femur morphology 1 | 14
abnormal humerus morphology 1 | 11
abnormal iris morphology 1 | 13
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal limb position 1 | 3
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal rib morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic lethality prior to t... 1 | 278
excessive tearing 1 | 2
female infertility 1 | 60
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
long tail 1 | 1
male infertility 1 | 123
narrow eye opening 1 | 12
prolonged RR interval 1 | 8
thick tail 1 | 1
trunk curl 1 | 16

Disease

Carcinoma 33 | 11,493
ovarian cancer 31 | 8,520
osteosarcoma 23 | 7,950
glioblastoma 22 | 5,792
Cancer 18 | 2,499
medulloblastoma, large-cell 18 | 6,241
Astrocytoma, Pilocytic 17 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
lung cancer 16 | 4,740
pancreatic cancer 16 | 2,398
atypical teratoid / rhabdoid tumor 15 | 5,112
ependymoma 15 | 4,679
psoriasis 15 | 6,694
Kidney cancer 13 | 2,613
group 3 medulloblastoma 13 | 4,104
non-small cell lung cancer 13 | 2,890
Breast cancer 12 | 3,578
adult high grade glioma 12 | 3,801
cystic fibrosis 12 | 1,696
invasive ductal carcinoma 12 | 2,951
lung adenocarcinoma 12 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
astrocytic glioma 10 | 2,597
oligodendroglioma 10 | 2,850
Autosomal recessive predisposition 9 | 1,442
Short stature 9 | 531
adrenocortical carcinoma 9 | 1,428
interstitial cystitis 9 | 2,312
lung carcinoma 9 | 2,843
pituitary cancer 9 | 1,972
primary pancreatic ductal adenocarcinoma 9 | 1,109
Pick disease 8 | 1,894
juvenile dermatomyositis 8 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
primitive neuroectodermal tumor 8 | 3,035
Brachydactyly 7 | 156
Duchenne muscular dystrophy 7 | 601
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
pediatric high grade glioma 7 | 1,064
subependymal giant cell astrocytoma 7 | 2,287
Acquired scoliosis 6 | 281
Curvature of spine 6 | 282
Intellectual disability 6 | 1,016
Osteogenesis imperfecta 6 | 34
Osteoporosis 6 | 363
astrocytoma 6 | 1,146
gastric carcinoma 6 | 807
group 4 medulloblastoma 6 | 1,855
malignant mesothelioma 6 | 3,232
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Cleft Palate 5 | 271
Cognitive delay 5 | 608
Cryptorchidism 5 | 296
Dull intelligence 5 | 645
Endometriosis 5 | 540
Epilepsy 5 | 792
Fibrodysplasia ossificans progressiva 5 | 17
Frontal bossing 5 | 157
Generalized osteopenia 5 | 99
Global developmental delay 5 | 608
Hyperkyphosis 5 | 111
Hyperphosphatemia 5 | 32
Kidney disease 5 | 430
Kyphosis deformity of spine 5 | 114
Liver cancer 5 | 604
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Obesity 5 | 678
Osteopenia 5 | 99
Polycystic ovary syndrome 5 | 360
Poor school performance 5 | 645
Schizophrenia 5 | 1,160
Seizures 5 | 596
active Crohn's disease 5 | 922
active ulcerative colitis 5 | 764
acute myeloid leukemia 5 | 783
acute quadriplegic myopathy 5 | 1,158
aldosterone-producing adenoma 5 | 665
colon cancer 5 | 1,478
dermatomyositis 5 | 966
Acquired metabolic disease 4 | 336
Acromegaly 4 | 51
Amyotrophic lateral sclerosis 4 | 451
Cushing's syndrome 4 | 48
Depressive disorder 4 | 409
Glaucoma 4 | 239
Hypertension 4 | 396
Hypothyroidism 4 | 122
Long narrow head 4 | 75
Multiple myeloma 4 | 1,332
Prostatic Neoplasms 4 | 495
Rheumatoid arthritis 4 | 1,191
esophageal adenocarcinoma 4 | 737
substance-related disorder 4 | 162

Tissue

Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Respiratory system 41 | 16,393
Urinary Tract 41 | 16,678
Blood and immune system 40 | 16,909
Digestive Tract 40 | 17,369
Male tissues 40 | 17,142
Nervous System 40 | 16,725
Skin and soft tissues 39 | 17,230
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 22 | 12,091
Enzyme 11 | 4,145
Transcription Factor 5 | 1,400
Kinase 2 | 634
GPCR 1 | 408
TF/Epigenetic 1 | 38
Transporter 1 | 473

GO Process

bone development 43 | 43
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
HMG box transcription factor BBX BBX Tbio Transcription Factor -1.55048 35.3 82
Extracellular sulfatase Sulf-2 SULF2 Tbio Enzyme -1.74398 67.0 221
Extracellular sulfatase Sulf-1 SULF1 Tbio Enzyme -1.90276 92.2 61
Protein spinster homolog 2 SPNS2 Tbio Non-IDG -1.42853 26.4 88
Putative sodium-coupled neutral amino acid transporter 10 SLC38A10 Tdark Transporter -0.27712 1.71 25
SH3 and PX domain-containing protein 2B SH3PXD2B Tbio Non-IDG -1.72872 53.3 71
Dymeclin DYM Tbio Non-IDG -1.51786 33.4 78
Ankyrin repeat domain-containing protein 11 ANKRD11 Tbio Non-IDG -2.55588 339.7 93