Development Level

Tbio 4 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

Carcinoma 5 | 11,493
osteosarcoma 5 | 7,950
atypical teratoid / rhabdoid tumor 4 | 5,112
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
ulcerative colitis 3 | 1,819
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cataract 2 | 297
Congenital Epicanthus 2 | 177
Downward slant of palpebral fissure 2 | 158
Hypertension 2 | 396
Liver Cirrhosis 2 | 181
Muscle hypotonia 2 | 571
Orbital separation excessive 2 | 244
Short stature 2 | 531
active ulcerative colitis 2 | 764
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
spina bifida 2 | 1,074
Achalasia 1 | 13
Angioectasias of the lip 1 | 4
Angioectasias of the tongue 1 | 2
Anophthalmos 1 | 13
Blastic phase chronic myeloid leukemia 1 | 58
Bone Diseases, Developmental 1 | 27
Brain Neoplasms 1 | 33
CATARACT 16, MULTIPLE TYPES 1 | 15
Cerebral Hemorrhage 1 | 42
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Cleft palate with cleft lip 1 | 23
Cleft uvula 1 | 27
Cri-Du-Chat syndrome 1 | 16
Decreased projection of midface 1 | 105
Diaphragmatic Hernia 1 | 40
Downturned corners of mouth 1 | 48
Erythrocytosis 1 | 8
Finger pad telangiectases 1 | 2
Fundus coloboma 1 | 18
Gastrointestinal telangiectasia 1 | 2
Hemangioma 1 | 69
Hepatitis 1 | 67
Hernia, Diaphragmatic 1 | 40
High pitched voice 1 | 23
Hypertension, Pulmonary 1 | 37
Hypoplasia of scrotum 1 | 24
Hypotrophic midface 1 | 105
Idiopathic pulmonary arterial hypertension 1 | 40
Ischemic stroke 1 | 4
LEOPARD syndrome 1 | 20
Lip telangiectases 1 | 4
Microphthalmia 1 | 76
Midface retrusion 1 | 105
Nail bed telangiectases 1 | 2
Nasal mucosa telangiectasia 1 | 2
Neoplasms 1 | 63
Noonan syndrome 1 | 34
Nuclear cataract 1 | 19
Nuclear non-senile cataract 1 | 18
Oral cleft 1 | 18
Otosclerosis 1 | 15
Palatal spider veins 1 | 2
Palate telangiectases 1 | 2
Prolactinoma 1 | 11
Pulmonary arteriovenous malformation 1 | 2
Pulmonary hypertension 1 | 85
Round face 1 | 45
Round, full face 1 | 45
Single transverse palmar crease 1 | 29
Small hand 1 | 36
Small midface 1 | 105
Spider veins of the lip 1 | 4
Spontaneous haematoma 1 | 8
Spontaneous, recurrent epistaxis 1 | 3
Systemic scleroderma 1 | 60
Telangiectasia of the skin 1 | 39
Telangiectasia, Hereditary Hemorrhagic 1 | 3
Temtamy preaxial brachydactyly syndrome 1 | 3
Thin hypoplastic alae nasi 1 | 51
Tongue telangiectasia 1 | 2
Tooth agenesis 1 | 44
Unilateral agenesis of kidney 1 | 20
Visceral angiomatosis 1 | 13

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Non-IDG 5 | 12,091
Kinase 2 | 634

GO Process

blood vessel endothelial cell ... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BMP-binding endothelial regulator protein BMPER Tbio Non-IDG -2.51174 317.7 120
Semaphorin-5A SEMA5A Tbio Non-IDG -1.82162 69.8 238
Integrin beta-1-binding protein 1 ITGB1BP1 Tbio Non-IDG -1.23128 20.8 138
Notch-regulated ankyrin repeat-containing protein NRARP Tbio Non-IDG -1.09051 13.9 99
Serine/threonine-protein kinase receptor R3 ACVRL1 Tchem Kinase -2.98370 969.8 432
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.21660 1658.5 540
Ephrin type-A receptor 2 EPHA2 Tclin Kinase -2.91920 874.6 873