Development Level

Tbio 123 | 11,445
Tchem 28 | 1,598
Tclin 15 | 613
Tdark 4 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 10 | 499
decreased vertical activity 5 | 208
embryonic lethality prior to t... 5 | 278
enlarged heart 4 | 210
abnormal gait 3 | 69
abnormal retina morphology 3 | 71
abnormal seminal vesicle morph... 3 | 114
decreased lean body mass 3 | 135
decreased mean corpuscular vol... 3 | 79
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
thrombocytopenia 3 | 56
tremors 3 | 39
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal retinal blood vessel ... 2 | 26
abnormal retinal vasculature m... 2 | 27
abnormal testis morphology 2 | 43
cataract 2 | 92
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating bilirubi... 2 | 19
decreased circulating glucose ... 2 | 126
decreased mean corpuscular hem... 2 | 50
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased erythrocyte cell num... 2 | 39
increased heart weight 2 | 62
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
increased spleen weight 2 | 10
small superior vagus ganglion 2 | 74
small testis 2 | 58
vertebral transformation 2 | 12
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal lens morphology 1 | 81
abnormal liver size 1 | 5
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spine curvature 1 | 9
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
dilated heart left ventricle 1 | 11
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
limb grasping 1 | 41
male infertility 1 | 123
pale yolk sac 1 | 25
polycystic kidney 1 | 15
short tibia 1 | 97
small kidney 1 | 16
small spleen 1 | 19
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Carcinoma 111 | 11,493
ovarian cancer 90 | 8,520
osteosarcoma 81 | 7,950
psoriasis 65 | 6,694
lung cancer 64 | 4,740
glioblastoma 62 | 5,792
medulloblastoma, large-cell 57 | 6,241
atypical teratoid / rhabdoid tumor 56 | 5,112
Cancer 55 | 2,499
pancreatic cancer 51 | 2,398
non-small cell lung cancer 45 | 2,890
ependymoma 44 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 43 | 1,962
intraductal papillary-mucinous neoplasm (IPMN) 42 | 3,291
Autosomal recessive predisposition 41 | 1,442
lung carcinoma 41 | 2,843
malignant mesothelioma 40 | 3,232
Breast cancer 39 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,989
invasive ductal carcinoma 39 | 2,951
adult high grade glioma 37 | 3,801
interstitial cystitis 37 | 2,312
lung adenocarcinoma 36 | 2,716
Astrocytoma, Pilocytic 35 | 3,081
group 3 medulloblastoma 35 | 4,104
tuberculosis 34 | 2,010
ulcerative colitis 34 | 1,819
Thrombocytopenia 28 | 197
oligodendroglioma 27 | 2,850
primitive neuroectodermal tumor 27 | 3,035
colon cancer 25 | 1,478
ductal carcinoma in situ 25 | 1,745
diabetes mellitus 24 | 1,728
pituitary cancer 24 | 1,972
Anemia 23 | 365
cystic fibrosis 23 | 1,696
Cerebrovascular disease 22 | 238
Epistaxis 22 | 43
astrocytic glioma 22 | 2,597
breast carcinoma 22 | 1,638
subependymal giant cell astrocytoma 22 | 2,287
Coronary artery disease 21 | 268
Ecchymosis 21 | 66
Increased tendency to bruise 21 | 66
Kidney cancer 21 | 2,613
Thrombophilia 20 | 38
Venous Thrombosis 20 | 47
gastric carcinoma 20 | 807
group 4 medulloblastoma 20 | 1,855
Liver Cirrhosis, Experimental 19 | 769
juvenile dermatomyositis 19 | 1,187
pancreatic carcinoma 19 | 562
Rheumatoid arthritis 18 | 1,191
Vascular disease 18 | 319
cutaneous lupus erythematosus 18 | 1,057
esophageal adenocarcinoma 18 | 737
Atherosclerosis 17 | 291
Pick disease 16 | 1,894
Multiple myeloma 15 | 1,332
Pulmonary embolism 15 | 55
Thrombosis 15 | 46
active ulcerative colitis 15 | 764
adrenocortical carcinoma 15 | 1,428
aldosterone-producing adenoma 15 | 665
astrocytoma 15 | 1,146
pediatric high grade glioma 15 | 1,064
primary pancreatic ductal adenocarcinoma 15 | 1,109
Decreased platelet count 14 | 111
Disseminated intravascular coagulation 14 | 38
Hypertension 14 | 396
active Crohn's disease 14 | 922
spina bifida 14 | 1,074
Atopic dermatitis 13 | 952
Bleeding time prolonged 13 | 31
Hypertensive disease 13 | 292
Intellectual disability 13 | 1,016
Liver Cirrhosis 13 | 181
Melanoma 13 | 711
Menorrhagia 13 | 25
Myocardial Infarction 13 | 151
Purpura 13 | 43
Schizophrenia 13 | 1,160
primary Sjogren syndrome 13 | 735
Bleeding tendency 12 | 37
Crohn's disease 12 | 321
Hepatomegaly 12 | 285
Kidney disease 12 | 430
Short stature 12 | 531
Splenomegaly 12 | 190
acute myeloid leukemia 12 | 783
dermatomyositis 12 | 966
hepatocellular carcinoma 12 | 547
mucosa-associated lymphoid tissue lymphoma 12 | 484
Down syndrome 11 | 499
Duchenne muscular dystrophy 11 | 601
Epilepsy 11 | 792
Waldenstrons macroglobulinemia 11 | 765
fibroadenoma 11 | 559
nasopharyngeal carcinoma 11 | 1,058

Tissue

Digestive Tract 153 | 17,369
Endocrine System 153 | 18,159
Male tissues 153 | 17,142
Liver and Pancreas 152 | 16,750
Female tissues 151 | 17,400
Blood and immune system 150 | 16,909
Skin and soft tissues 150 | 17,230
Urinary Tract 149 | 16,678
Respiratory system 147 | 16,393
Nervous System 143 | 16,725
Cardiovascular System 135 | 15,192

Target Family

Non-IDG 91 | 12,091
Enzyme 34 | 4,145
Transcription Factor 16 | 1,400
Ion Channel 8 | 344
Kinase 8 | 634
Epigenetic 7 | 242
GPCR 5 | 408
Nuclear Receptor 1 | 48

GO Process

blood coagulation 170 | 170
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Platelet glycoprotein V GP5 Tbio Non-IDG -2.81536 644.5 88
Proteinase-activated receptor 4 F2RL3 Tchem GPCR -1.50044 34.1 276
Hemoglobin subunit delta HBD Tbio Non-IDG -2.72143 515.2 30
Phylloquinone omega-hydroxylase CYP4F11 CYP4F11 Tbio Enzyme -0.71213 6.60 96
Zinc finger protein ZFPM2 ZFPM2 Tbio Transcription Factor -1.78912 62.9 93
GTP:AMP phosphotransferase AK3, mitochondrial AK3 Tbio Kinase -1.37969 23.5 249
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Megakaryocyte and platelet inhibitory receptor G6b MPIG6B Tbio Non-IDG -1.00429 11.8 53
Endothelial protein C receptor PROCR Tbio Non-IDG -2.70271 541.0 367
Vitamin K-dependent gamma-carboxylase GGCX Tclin Enzyme -1.90296 79.3 192