Development Level

Tbio 28 | 11,445
Tchem 9 | 1,598
Tclin 7 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

increased neutrophil cell numb... 2 | 46
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
impaired righting response 1 | 26
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
polycystic kidney 1 | 15
small superior vagus ganglion 1 | 74

Disease

Carcinoma 29 | 11,493
psoriasis 25 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
lung cancer 18 | 4,740
osteosarcoma 18 | 7,950
ovarian cancer 18 | 8,520
glioblastoma 17 | 5,792
medulloblastoma, large-cell 16 | 6,241
Breast cancer 15 | 3,578
atypical teratoid / rhabdoid tumor 15 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
invasive ductal carcinoma 15 | 2,951
lung carcinoma 15 | 2,843
malignant mesothelioma 15 | 3,232
Astrocytoma, Pilocytic 14 | 3,081
Cancer 14 | 2,499
non-small cell lung cancer 14 | 2,890
pancreatic cancer 13 | 2,398
tuberculosis 13 | 2,010
Hypertension 12 | 396
adult high grade glioma 12 | 3,801
breast carcinoma 12 | 1,638
ependymoma 12 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
cystic fibrosis 11 | 1,696
ductal carcinoma in situ 11 | 1,745
interstitial cystitis 11 | 2,312
lung adenocarcinoma 11 | 2,716
Kidney cancer 10 | 2,613
colon cancer 10 | 1,478
diabetes mellitus 10 | 1,728
Schizophrenia 9 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Cerebrovascular disease 8 | 238
Coronary artery disease 8 | 268
Heart disease 8 | 306
Hypertensive disease 8 | 292
Rheumatoid arthritis 8 | 1,191
astrocytic glioma 8 | 2,597
dermatomyositis 8 | 966
Alzheimer's disease 7 | 658
Autistic Disorder 7 | 364
Autosomal recessive predisposition 7 | 1,442
Depressive disorder 7 | 409
Obesity 7 | 678
group 3 medulloblastoma 7 | 4,104
juvenile dermatomyositis 7 | 1,187
mucosa-associated lymphoid tissue lymphoma 7 | 484
oligodendroglioma 7 | 2,850
pituitary cancer 7 | 1,972
ulcerative colitis 7 | 1,819
Asthma 6 | 385
Duchenne muscular dystrophy 6 | 601
Liver Cirrhosis, Experimental 6 | 769
Mood Disorders 6 | 184
Multiple Sclerosis 6 | 540
Osteoporosis 6 | 363
Pick disease 6 | 1,894
Vascular disease 6 | 319
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
fibroadenoma 6 | 559
Arthritis, Rheumatoid 5 | 174
Atherosclerosis 5 | 291
Bipolar Disorder 5 | 666
Cardiomyopathies 5 | 110
Cardiovascular Diseases 5 | 59
Cerebrovascular accident 5 | 63
Intellectual disability 5 | 1,016
Kidney disease 5 | 430
Major Depressive Disorder 5 | 301
Myocardial Infarction 5 | 151
Pain 5 | 103
Strabismus 5 | 270
active Crohn's disease 5 | 922
active ulcerative colitis 5 | 764
cutaneous lupus erythematosus 5 | 1,057
group 4 medulloblastoma 5 | 1,855
medulloblastoma 5 | 720
pancreatic carcinoma 5 | 562
primary Sjogren syndrome 5 | 735
primitive neuroectodermal tumor 5 | 3,035
Alcoholic Intoxication, Chronic 4 | 289
Anemia 4 | 365
Attention deficit hyperactivity disorder 4 | 278
Brain Ischemia 4 | 110
Cardiovascular system disease 4 | 246
Colonic Neoplasms 4 | 142
Constipation 4 | 181
Dull intelligence 4 | 645
Epilepsy 4 | 792
Liver Cirrhosis 4 | 181
Migraine 4 | 83
Seizures 4 | 596
Unipolar Depression 4 | 250
Ventricular Septal Defects 4 | 119
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
hepatocellular carcinoma 4 | 547
limb girdle muscular dystrophy 2A 4 | 213
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Endocrine System 44 | 18,159
Male tissues 43 | 17,142
Digestive Tract 42 | 17,369
Nervous System 41 | 16,725
Skin and soft tissues 41 | 17,230
Urinary Tract 41 | 16,678
Blood and immune system 40 | 16,909
Female tissues 40 | 17,400
Liver and Pancreas 40 | 16,750
Respiratory system 40 | 16,393
Cardiovascular System 38 | 15,192

Target Family

Non-IDG 16 | 12,091
GPCR 12 | 408
Enzyme 7 | 4,145
Transcription Factor 7 | 1,400
Epigenetic 1 | 242
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

blood circulation 45 | 45
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Urotensin-2 receptor UTS2R Tchem GPCR -1.95094 62.5 182
Friend leukemia integration 1 transcription factor FLI1 Tbio Transcription Factor -1.82504 66.8 454
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.48671 270.6 121
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
TBC1 domain family member 8 TBC1D8 Tdark Non-IDG 0.21 0.48 69
Coagulation factor V F5 Tbio Non-IDG -2.73955 525.3 198
Elastin ELN Tbio Non-IDG -3.36288 2144.5 299
Myoferlin MYOF Tbio Non-IDG -1.89937 75.2 63
Pro-neuropeptide Y NPY Tbio Non-IDG -3.83401 7433.3 432
Cardiac phospholamban PLN Tbio Non-IDG -1.93701 85.8 365