Development Level

Tbio 5 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal gait 1 | 69
aorta dilation 1 | 3
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased lean body mass 1 | 172
male infertility 1 | 123
prolonged QT interval 1 | 38
shortened QT interval 1 | 4

Disease

ovarian cancer 5 | 8,520
Carcinoma 4 | 11,493
glioblastoma 3 | 5,792
osteosarcoma 3 | 7,950
Breast cancer 2 | 3,578
Cancer 2 | 2,499
X-linked cerebral adrenoleukodystrophy 2 | 116
diabetes mellitus 2 | 1,728
medulloblastoma 2 | 720
medulloblastoma, large-cell 2 | 6,241
psoriasis 2 | 6,694
Abnormal color vision 1 | 31
Abnormal visual evoked potential 1 | 26
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Alcohol withdrawal syndrome 1 | 20
Amyotrophic lateral sclerosis 1 | 451
Anosmia 1 | 22
Arsenic Poisoning 1 | 62
Arthralgia 1 | 90
Axonal degeneration/regeneration 1 | 7
Babinski Reflex 1 | 100
Blind spot located at fixation point 1 | 21
CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2A2 (disorder) 1 | 1
Cardiomegaly 1 | 116
Charcot-Marie-Tooth disease 1 | 62
Color vision defect 1 | 33
Color vision defect, severe 1 | 31
Congenital pes cavus 1 | 88
Contracture 1 | 96
Contracture of joint 1 | 93
Decreased motor NCV 1 | 22
Decreased number of large and small myelinated fibers 1 | 20
Decreased tendon reflex 1 | 122
Decreased to absent deep tendon reflexes 1 | 42
Decreased visual acuity, slowly progressive 1 | 13
Dermatologic disorders 1 | 93
Diphtheria 1 | 40
Distal amyotrophy 1 | 51
Distal limb muscle weakness due to peripheral neuropathy 1 | 62
Distal muscle weakness 1 | 62
Distal sensory impairment 1 | 52
Distal sensory impairment of all modalities 1 | 7
Dysmetric saccades 1 | 9
Flexion contracture 1 | 93
Flexion contractures of joints 1 | 93
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Gaucher disease type 1 1 | 180
Hammer Toe 1 | 23
Hereditary motor and sensory neuropathy with optic atrophy (disorder) 1 | 2
Highly variable severity 1 | 157
Hoarse voice due to vocal cord paresis 1 | 3
Infantile onset 1 | 238
Infertility 1 | 188
Insulin Resistance 1 | 72
Joint stiffness 1 | 84
Lipoma 1 | 32
Lumbar lordosis 1 | 35
Lymphogranuloma venereum 1 | 11
Multiple lipomata 1 | 7
Muscle weakness of limb 1 | 21
Neurodegenerative disease 1 | 414
Neuropathy 1 | 261
Onion bulb formation 1 | 19
Oophoritis 1 | 10
Ovarian dysfunction 1 | 18
Pain 1 | 103
Pallor of optic disc 1 | 39
Paraquat lung 1 | 2
Paresthesia 1 | 32
Partial Paralysis (Paresis) Vocal Cords 1 | 3
Peripheral axonal atrophy 1 | 4
Polyneuropathy 1 | 64
Premature ovarian failure 1 | 65
Proximal muscle weakness 1 | 47
Proximal neurogenic muscle weakness 1 | 47
Pulmonary Fibrosis 1 | 106
RETINITIS PIGMENTOSA 27 1 | 4
Reflex, Deep Tendon, Absent 1 | 92
Romberg's sign positive 1 | 4
Scotoma, Central 1 | 21
Shoulder impingement syndrome 1 | 4
Skin Diseases 1 | 71
Slow decrease in visual acuity 1 | 13
Slow progression 1 | 89
Smooth muscle tumor 1 | 13
Spastic Paraplegia, Hereditary 1 | 5
Susceptibility to viral and mycobacterial infections 1 | 11
Tetanus 1 | 68
Tinnitus 1 | 19
Ureteral obstruction 1 | 33
Uterine fibroid 1 | 28
Variable expressivity 1 | 157
Vocal cord paresis in severe cases 1 | 3
Weakness of vocal cord 1 | 3
cataract 14 multiple types 1 | 5
inflammatory breast cancer 1 | 286
limb girdle muscular dystrophy 2B 1 | 40

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 1 | 4,145
Epigenetic 1 | 242

GO Process

blastocyst formation 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Splicing factor 3B subunit 6 SF3B6 Tbio Non-IDG -0.65964 4.59 100
Mitofusin-2 MFN2 Tbio Non-IDG -2.68784 484.6 447
Lysine-specific demethylase 4C KDM4C Tchem Epigenetic -1.64807 46.2 208
Zona pellucida sperm-binding protein 3 ZP3 Tbio Non-IDG -2.77948 603.6 79
Ribosomal RNA-processing protein 7 homolog A RRP7A Tdark Non-IDG 0.60 0.29 88
60S ribosomal protein L7-like 1 RPL7L1 Tdark Non-IDG 0.41 0.39 57
Ski-like protein SKIL Tbio Non-IDG -2.19816 173.0 352
E3 ubiquitin-protein ligase CCNB1IP1 CCNB1IP1 Tbio Enzyme -1.11738 15.2 152