Development Level

Tbio 12 | 11,651
Tchem 8 | 1,388
Tclin 3 | 612

IMPC Phenotype

abnormal behavior 2 | 298
abnormal lung morphology 1 | 26
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hyperactivity 1 | 148
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 172
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499
thin ventricular wall 1 | 24

Disease

Carcinoma 16 | 11,493
Cancer 12 | 2,499
Cholestasis 12 | 155
osteosarcoma 11 | 7,950
lung cancer 9 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Liver disease 8 | 237
ovarian cancer 8 | 8,520
glioblastoma 7 | 5,792
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Autosomal recessive predisposition 6 | 1,442
Bilirubin metabolic disorder 6 | 41
Kidney cancer 6 | 2,613
active Crohn's disease 6 | 922
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
Rheumatoid arthritis 5 | 1,191
cystic fibrosis 5 | 1,696
invasive ductal carcinoma 5 | 2,951
Conjugated hyperbilirubinemia 4 | 14
Diarrhea 4 | 253
Icterus 4 | 82
Keratoconjunctivitis sicca 4 | 25
Prevention of Cardiac Transplant Rejection 4 | 15
Prevention of Kidney Transplant Rejection 4 | 17
Prevention of Liver Transplant Rejection 4 | 15
Severe Recalcitrant Psoriasis 4 | 12
Tear film insufficiency 4 | 15
aldosterone-producing adenoma 4 | 665
atypical teratoid / rhabdoid tumor 4 | 5,112
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
pituitary cancer 4 | 1,972
Breast Neoplasms 3 | 445
Cholangitis 3 | 32
Cholelithiasis 3 | 33
Cholestasis of pregnancy 3 | 5
Failure to gain weight 3 | 365
Hepatitis B 3 | 108
Hepatomegaly 3 | 285
Infantile onset 3 | 238
Intestinal malabsorption of fat 3 | 5
Intrahepatic cholestasis 3 | 20
Liver Cirrhosis 3 | 181
Liver Cirrhosis, Experimental 3 | 769
Mammary Neoplasms 3 | 425
Pediatric failure to thrive 3 | 365
Progressive intrahepatic cholestasis 3 | 4
Prostatic Neoplasms 3 | 495
active ulcerative colitis 3 | 764
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
ependymoma 3 | 4,679
group 4 medulloblastoma 3 | 1,855
mucosa-associated lymphoid tissue lymphoma 3 | 484
nephrosclerosis 3 | 333
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
Abnormal pigmentation 2 | 25
Abnormality of the skeletal system 2 | 11
Adverse reaction to drug 2 | 61
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Chemical and Drug Induced Liver Injury 2 | 195
Colorectal Neoplasms 2 | 243
Drug-Related Side Effects and Adverse Reactions 2 | 62
Endometriosis 2 | 540
Fatty liver disease 2 | 103
HYPERBILIRUBINEMIA, ROTOR TYPE 2 | 2
Leber congenital amaurosis 2 | 69
Liver carcinoma 2 | 240
Lung Neoplasms 2 | 232
Melanoma 2 | 711
Muscular Diseases 2 | 27
Myopathy 2 | 185
Neonatal Jaundice 2 | 30
Osteoporosis 2 | 363
Pancreatitis 2 | 123
Pick disease 2 | 1,894
Pruritus 2 | 58
Rotor Syndrome 2 | 2
Skin cancer 2 | 469
adrenocortical carcinoma 2 | 1,428
chronic rhinosinusitis 2 | 512
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
medulloblastoma 2 | 720
non-small cell lung carcinoma 2 | 317
oligodendroglioma 2 | 2,850
posterior fossa group A ependymoma 2 | 468
primary pancreatic ductal adenocarcinoma 2 | 1,109
ulcerative colitis 2 | 1,819

Tissue

Liver and Pancreas 23 | 16,750
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Urinary Tract 22 | 16,678
Female tissues 21 | 17,400
Male tissues 21 | 17,142
Skin and soft tissues 21 | 17,230
Blood and immune system 20 | 16,909
Respiratory system 18 | 16,393
Nervous System 17 | 16,725
Cardiovascular System 15 | 15,192

Target Family

Transporter 13 | 473
Non-IDG 5 | 12,091
Enzyme 2 | 4,145
Nuclear Receptor 2 | 48
Epigenetic 1 | 242

GO Process

bile acid and bile salt transp... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bile acid receptor NR1H4 Tclin Nuclear Receptor -2.57379 350.3 293
Solute carrier organic anion transporter family member 1B1 SLCO1B1 Tchem Transporter -2.77788 574.0 124
Organic solute transporter subunit alpha SLC51A Tbio Transporter -1.94606 84.5 82
Ileal sodium/bile acid cotransporter SLC10A2 Tclin Transporter -2.67747 471.5 142
Aldo-keto reductase family 1 member C1 AKR1C1 Tchem Enzyme -3.12161 1290.1 172
Nuclear receptor coactivator 2 NCOA2 Tbio Non-IDG -2.17388 142.6 197
Canalicular multispecific organic anion transporter 2 ABCC3 Tbio Transporter -2.46032 287.4 214
Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 Tbio Non-IDG -2.47325 361.5 525
Sodium/bile acid cotransporter 4 SLC10A4 Tbio Transporter -0.88990 11.0 77
Solute carrier organic anion transporter family member 1A2 SLCO1A2 Tbio Transporter -2.54990 331.6 79