Development Level

Tbio 30 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
enlarged heart 2 | 210
abnormal bone structure 1 | 187
abnormal ear morphology 1 | 9
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
absent startle reflex 1 | 24
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased body length 1 | 32
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

Carcinoma 24 | 11,493
ovarian cancer 20 | 8,520
psoriasis 16 | 6,694
atypical teratoid / rhabdoid tumor 14 | 5,112
medulloblastoma, large-cell 14 | 6,241
Cancer 12 | 2,499
glioblastoma 12 | 5,792
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
non-small cell lung cancer 12 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung cancer 11 | 4,740
osteosarcoma 11 | 7,950
ependymoma 10 | 4,679
spina bifida 10 | 1,074
Breast cancer 9 | 3,578
ductal carcinoma in situ 9 | 1,745
invasive ductal carcinoma 9 | 2,951
pancreatic cancer 9 | 2,398
adult high grade glioma 8 | 3,801
group 3 medulloblastoma 7 | 4,104
lung adenocarcinoma 7 | 2,716
Astrocytoma, Pilocytic 6 | 3,081
Kidney cancer 6 | 2,613
astrocytic glioma 6 | 2,597
primitive neuroectodermal tumor 6 | 3,035
ulcerative colitis 6 | 1,819
cystic fibrosis 5 | 1,696
subependymal giant cell astrocytoma 5 | 2,287
Atopic dermatitis 4 | 952
Pick disease 4 | 1,894
Prostatic Neoplasms 4 | 495
Rheumatoid arthritis 4 | 1,191
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
esophageal adenocarcinoma 4 | 737
group 4 medulloblastoma 4 | 1,855
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
Breast Neoplasms 3 | 445
Cell Transformation, Neoplastic 3 | 97
Liver cancer 3 | 604
Mammary Neoplasms 3 | 425
Neoplastic Cell Transformation 3 | 89
Schizophrenia 3 | 1,160
Splenomegaly 3 | 190
active Crohn's disease 3 | 922
fibroadenoma 3 | 559
malignant mesothelioma 3 | 3,232
nasopharyngeal carcinoma 3 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Adenocarcinoma 2 | 122
Animal Mammary Neoplasms 2 | 136
Bipolar Disorder 2 | 666
Down syndrome 2 | 499
Endometriosis 2 | 540
Hyperlipidemia 2 | 43
Inflammatory bowel disease 2 | 151
Leber congenital amaurosis 2 | 69
Lung Neoplasms 2 | 232
Lymphoid leukemia 2 | 160
Mammary Neoplasms, Animal 2 | 136
Melanoma 2 | 711
Mental Depression 2 | 333
Neoplasms 2 | 63
Nonsyndromic deafness 2 | 142
Respiratory Distress Syndrome, Adult 2 | 40
Retinitis Pigmentosa 2 | 226
Stomach Neoplasms 2 | 300
Substance-Related Disorders 2 | 115
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
hypoparathyroidism-retardation-dysmorphism syndrome 2 | 7
interstitial lung disease 2 | 298
medulloblastoma 2 | 720
posterior fossa group B ependymoma 2 | 416
progressive supranuclear palsy 2 | 676
urothelial carcinoma 2 | 318
Cellulitis 1 | 20
Cervical cancer 1 | 24
Congenital diaphragmatic hernia 1 | 67
Defective enamel matrix 1 | 35
Dysplasia of tooth enamel 1 | 35
Increased hepatocellular carcinoma risk 1 | 27
Increased incidence of hepatocellular carcinoma 1 | 27
Inflammatory Bowel Diseases 1 | 35
Intestinal Neoplasms 1 | 12
Keloid 1 | 37
Ovarian dysfunction 1 | 18
Premature ovarian failure 1 | 65
Type 1 Diabetes Mellitus Treatment Adjunct 1 | 4
Type 2 Diabetes Mellitus Treatment Adjunct 1 | 7

Tissue

Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Male tissues 32 | 17,142
Nervous System 32 | 16,725
Respiratory system 32 | 16,393
Urinary Tract 32 | 16,678
Blood and immune system 31 | 16,909
Cardiovascular System 31 | 15,192
Liver and Pancreas 31 | 16,750
Skin and soft tissues 31 | 17,230

Target Family

Non-IDG 28 | 12,091
Enzyme 2 | 4,145
Transcription Factor 2 | 1,400
Kinase 1 | 634

GO Process

bicellular tight junction asse... 33 | 33
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin-specific chaperone D TBCD Tbio Non-IDG -1.71996 50.5 50
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Programmed cell death 6-interacting protein PDCD6IP Tbio Non-IDG -1.59404 35.1 216
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
Ras-related protein Rab-13 RAB13 Tbio Enzyme -1.40524 27.4 73
Alpha-actinin-4 ACTN4 Tbio Non-IDG -2.22522 178.2 300
Claudin-3 CLDN3 Tbio Non-IDG -2.37681 227.3 358
InaD-like protein PATJ Tbio Non-IDG -1.94236 82.0 103
MARVEL domain-containing protein 3 MARVELD3 Tbio Non-IDG -0.76427 6.41 40
MICAL-like protein 2 MICALL2 Tbio Non-IDG -0.91217 11.2 67