Development Level

Tbio 15 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal startle reflex 1 | 15
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hydrometra 1 | 53
increased bone mineral density 1 | 72
increased circulating insulin ... 1 | 3
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
small superior vagus ganglion 1 | 74

Disease

Carcinoma 15 | 11,493
Cancer 14 | 2,499
osteosarcoma 12 | 7,950
ovarian cancer 12 | 8,520
psoriasis 12 | 6,694
atypical teratoid / rhabdoid tumor 9 | 5,112
glioblastoma 9 | 5,792
medulloblastoma, large-cell 8 | 6,241
Breast cancer 7 | 3,578
group 3 medulloblastoma 7 | 4,104
Kidney cancer 6 | 2,613
Osteoporosis 6 | 363
ependymoma 6 | 4,679
lung cancer 6 | 4,740
adrenocortical carcinoma 5 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
primitive neuroectodermal tumor 5 | 3,035
Intellectual disability 4 | 1,016
Liver cancer 4 | 604
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
adult high grade glioma 4 | 3,801
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
medulloblastoma 4 | 720
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
osteoporosis-pseudoglioma syndrome 4 | 9
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Carcinoma, Hepatocellular 3 | 228
Cognitive delay 3 | 608
Colonic Neoplasms 3 | 142
Dull intelligence 3 | 645
Endometrial cancer 3 | 311
Familial adenomatous polyposis 3 | 32
Global developmental delay 3 | 608
Increased hepatocellular carcinoma risk 3 | 27
Increased incidence of hepatocellular carcinoma 3 | 27
Juvenile osteoporosis 3 | 4
Liver carcinoma 3 | 240
Long philtrum 3 | 137
Low intelligence 3 | 645
Malabsorption 3 | 82
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Micronodular cirrhosis 3 | 12
Orbital separation excessive 3 | 244
Osteoporosis, Juvenile 3 | 4
Parkinson's disease 3 | 392
Pick disease 3 | 1,894
Poor school performance 3 | 645
Robinow syndrome 3 | 11
Short stature 3 | 531
Somatic mutation 3 | 61
Stomach Neoplasms 3 | 300
Subacute progressive viral hepatitis 3 | 9
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
pancreatic cancer 3 | 2,398
Abdominal Pain 2 | 98
Abnormality of retinal pigmentation 2 | 111
Big calvaria 2 | 147
Breast Neoplasms 2 | 445
Colorectal Neoplasms 2 | 243
Craniofacial Abnormalities 2 | 151
Frequent fractures 2 | 53
Frontal bossing 2 | 157
Headache 2 | 37
Heart conduction disease 2 | 83
High forehead 2 | 102
Highly variable severity 2 | 157
Increased fracture rate 2 | 53
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Infantile onset 2 | 238
Large intestine cancer 2 | 126
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Muscular atrophy 2 | 71
Nausea and vomiting 2 | 97
Neoplasm Metastasis 2 | 168
Osteoarthritis 2 | 184
Retinal pigment epithelial abnormality 2 | 111
Skin cancer 2 | 469
Tall forehead 2 | 102
Variable expressivity 2 | 157
Varying degree of multiple fractures 2 | 53
posterior fossa group A ependymoma 2 | 468

Tissue

Female tissues 21 | 17,400
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Nervous System 20 | 16,725
Blood and immune system 19 | 16,909
Male tissues 19 | 17,142
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Liver and Pancreas 18 | 16,750
Cardiovascular System 17 | 15,192

Target Family

Non-IDG 16 | 12,091
GPCR 3 | 408
Kinase 2 | 634
Enzyme 1 | 4,145

GO Process

beta-catenin destruction compl... 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Low-density lipoprotein receptor-related protein 5 LRP5 Tbio Non-IDG -3.10429 1247.5 302
APC membrane recruitment protein 1 AMER1 Tbio Non-IDG -2.74178 542.4 84
Adenomatous polyposis coli protein APC Tbio Non-IDG -1.90646 66.5 508
Frizzled-5 FZD5 Tbio GPCR -1.54924 30.5 307
Frizzled-1 FZD1 Tbio GPCR -2.07049 78.4 286
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PPP1CA Tchem Enzyme -2.17010 139.0 378
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -3.00390 610.8 955
Protein Wnt-8b WNT8B Tbio Non-IDG -1.37226 19.9 163
Axin-1 AXIN1 Tbio Non-IDG -2.52218 301.0 370
Segment polarity protein dishevelled homolog DVL-2 DVL2 Tbio Non-IDG -1.87063 68.4 288