Development Level

Tclin 6 | 613
Tbio 1 | 11,445
Tchem 1 | 1,598

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal epididymis morphology 1 | 42
enlarged heart 1 | 210
preweaning lethality, incomple... 1 | 499

Disease

Nicotine dependence 7 | 54
Carcinoma 6 | 11,493
Schizophrenia 6 | 1,160
Frontal lobe epilepsy 5 | 10
Seizures 5 | 596
Alcohol dependence 4 | 107
Alcoholic Intoxication, Chronic 4 | 289
Attention deficit hyperactivity disorder 3 | 278
Autistic Disorder 3 | 364
Chronic obstructive pulmonary disease 3 | 184
Cocaine Dependence 3 | 51
Epilepsy 3 | 792
Inflammation 3 | 120
Lung Neoplasms 3 | 232
Smoking cessation assistance 3 | 8
Substance Withdrawal Syndrome 3 | 55
TOBACCO ADDICTION, SUSCEPTIBILITY TO 3 | 12
TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding) 3 | 12
glioblastoma 3 | 5,792
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
psoriasis 3 | 6,694
substance-related disorder 3 | 162
Alcoholism 2 | 45
Alzheimer's disease 2 | 658
Anxiety Disorders 2 | 38
Astrocytoma, Pilocytic 2 | 3,081
Attention Deficit Disorder with Hyperactivity 2 | 21
Autosomal dominant nocturnal frontal lobe epilepsy 2 | 4
Cancer 2 | 2,499
Controlled Hypotension 2 | 6
Epilepsy, Frontal Lobe 2 | 4
Heart disease 2 | 306
Hypertensive Emergencies 2 | 10
Hypertensive disorder 2 | 56
Muscle relaxation, function 2 | 8
Niacin deficiency 2 | 5
Nicotine Withdrawal Symptoms 2 | 5
Pellagra 2 | 26
Pulmonary edema 2 | 17
Sleep Wake Disorders 2 | 7
Sudden infant death syndrome 2 | 32
Tobacco Use Disorder 2 | 12
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
osteosarcoma 2 | 7,950
primitive neuroectodermal tumor 2 | 3,035
Adenocarcinoma 1 | 122
Adverse reaction to drug 1 | 61
Animal Mammary Neoplasms 1 | 136
Cardiomegaly 1 | 116
Chemical and Drug Induced Liver Injury 1 | 195
Cocaine abuse 1 | 19
Crohn Disease 1 | 45
Depressed mood 1 | 17
Developmental Disabilities 1 | 23
Diabetes Mellitus, Experimental 1 | 108
Drug-Related Side Effects and Adverse Reactions 1 | 62
Dyslipidemias 1 | 27
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
General anesthesia 1 | 53
Hyperglycemia 1 | 137
Hyperinsulinism 1 | 133
Hyperlipidemia 1 | 43
Hypertriglyceridemia 1 | 17
Hypothermia, natural 1 | 17
Insulin Resistance 1 | 72
Kidney Diseases 1 | 114
Kidney Failure, Chronic 1 | 46
Liver disease 1 | 237
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Microphthalmia with limb anomalies 1 | 40
Muscle Weakness 1 | 170
Muscular Diseases 1 | 27
Myasthenia gravis 1 | 23
Myasthenic Syndrome, Congenital, 4C, Associated With Acetylcholine Receptor Deficiency 1 | 5
Myasthenic Syndrome, Congenital, with Facial Dysmorphism, associated with Acetylcholine Receptor Deficiency 1 | 4
Myocardial Reperfusion Injury 1 | 37
Narrow face 1 | 54
Neoplasms 1 | 63
Nerve Degeneration 1 | 121
Nervous System Diseases 1 | 53
Non-alcoholic Fatty Liver Disease 1 | 42
Ophthalmoplegia 1 | 106
Pain agnosia 1 | 104
Prenatal onset 1 | 139
Primary Prevention of Coronary Heart Disease 1 | 4
Reflex, Abnormal 1 | 5
Respiratory function loss 1 | 121
Seizures, Focal 1 | 14
Thin face 1 | 54
Withdrawal disorder 1 | 19
nervous system disorder 1 | 53
non-small cell lung carcinoma 1 | 317

Tissue

Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Nervous System 8 | 16,725
Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Male tissues 6 | 17,142
Respiratory system 6 | 16,393
Cardiovascular System 5 | 15,192

Target Family

Ion Channel 7 | 344
Nuclear Receptor 1 | 48

GO Process

behavioral response to nicotin... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuronal acetylcholine receptor subunit beta-2 CHRNB2 Tclin Ion Channel -1.62448 37.6 174
Neuronal acetylcholine receptor subunit alpha-7 CHRFAM7A Tchem Ion Channel -1.81173 87.7 226
Neuronal acetylcholine receptor subunit beta-4 CHRNB4 Tclin Ion Channel -1.57182 33.7 130
Acetylcholine receptor subunit beta CHRNB1 Tclin Ion Channel -1.26222 17.9 180
Peroxisome proliferator-activated receptor alpha PPARA Tclin Nuclear Receptor -3.37176 2457.9 501
Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 Tbio Ion Channel -2.15575 143.1 237
Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 Tclin Ion Channel -3.62589 4263.7 202
Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 Tclin Ion Channel -1.99577 92.1 193