Development Level

Tbio 21 | 11,445
Tchem 9 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
abnormal coat- hair morphology 1 | 19
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
increased aggression 1 | 4
increased circulating HDL chol... 1 | 80
increased circulating glucose ... 1 | 24
increased grip strength 1 | 41
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 20 | 8,520
Carcinoma 19 | 11,493
osteosarcoma 19 | 7,950
medulloblastoma, large-cell 17 | 6,241
Cancer 16 | 2,499
lung cancer 16 | 4,740
group 3 medulloblastoma 14 | 4,104
malignant mesothelioma 14 | 3,232
glioblastoma 13 | 5,792
psoriasis 13 | 6,694
atypical teratoid / rhabdoid tumor 12 | 5,112
primitive neuroectodermal tumor 11 | 3,035
Breast cancer 9 | 3,578
Autosomal recessive predisposition 8 | 1,442
adult high grade glioma 7 | 3,801
lung adenocarcinoma 7 | 2,716
Cockayne syndrome 6 | 60
Xeroderma pigmentosum 6 | 43
diabetes mellitus 6 | 1,728
invasive ductal carcinoma 6 | 2,951
non-small cell lung cancer 6 | 2,890
Dull intelligence 5 | 645
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Short stature 5 | 531
ependymoma 5 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Astrocytoma, Pilocytic 4 | 3,081
Cataract 4 | 297
Epilepsy 4 | 792
Hydrocephalus 4 | 152
Hypogonadism 4 | 173
Kidney cancer 4 | 2,613
Lens Opacities 4 | 231
Myocardial Infarction 4 | 151
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
Seizures 4 | 596
Waldenstrons macroglobulinemia 4 | 765
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Acquired immunodeficiency syndrome 3 | 197
Adenoma 3 | 167
Alzheimer's disease 3 | 658
Atrophic condition of skin 3 | 25
Basal cell carcinoma 3 | 54
Bladder Neoplasm 3 | 112
Bloom syndrome 3 | 29
Chronic Lymphocytic Leukemia 3 | 262
Cryptorchidism 3 | 296
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Esophageal Squamous Cell Carcinoma 3 | 77
Failure to gain weight 3 | 365
Fanconi anemia 3 | 56
Fetal Growth Retardation 3 | 189
Heart disease 3 | 306
Hypoplastic mandible condyle 3 | 275
Infant, Small for Gestational Age 3 | 176
Insulin Resistance 3 | 72
Intrauterine retardation 3 | 176
Lung Neoplasms 3 | 232
Lung disease 3 | 142
Mandibular hypoplasia 3 | 275
Melanoma 3 | 711
Micrognathism 3 | 275
Micronuclei, Chromosome-Defective 3 | 25
Neurodegenerative disease 3 | 414
Optic Atrophy 3 | 242
Osteoporosis 3 | 363
Pancreatitis 3 | 123
Pediatric failure to thrive 3 | 365
Photosensitive trichothiodystrophy 3 | 30
Photosensitivity of skin 3 | 51
Poikiloderma 3 | 14
Small head 3 | 374
Spider Veins 3 | 17
Squamous cell carcinoma of esophagus 3 | 77
Stomach Neoplasms 3 | 300
Strabismus 3 | 270
Telangiectasis 3 | 36
Urinary Bladder Neoplasms 3 | 114
Werner syndrome 3 | 29
Xeroderma pigmentosum group D 3 | 33
Xeroderma pigmentosum group G 3 | 16
astrocytoma 3 | 1,146
hepatocellular carcinoma 3 | 547
nasopharyngeal carcinoma 3 | 1,058
progressive supranuclear palsy 3 | 676
Fever 2 | 138
Keratitis 2 | 62
Tremor 2 | 113
hearing impairment 2 | 199

Tissue

Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Blood and immune system 29 | 16,909
Urinary Tract 29 | 16,678
Cardiovascular System 28 | 15,192

Target Family

Enzyme 18 | 4,145
Non-IDG 7 | 12,091
Transcription Factor 4 | 1,400
Epigenetic 2 | 242

GO Process

base-excision repair 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-dependent DNA helicase Q4 RECQL4 Tbio Enzyme 0.00000 0
G/T mismatch-specific thymine DNA glycosylase TDG Tbio Enzyme -2.46252 297.6 225
Single-strand selective monofunctional uracil DNA glycosylase SMUG1 Tbio Enzyme -4.31831 20587.4 199
Uracil-DNA glycosylase UNG Tbio Enzyme -2.82957 680.9 352
N-glycosylase/DNA lyase OGG1 Tbio Enzyme -3.26147 1834.9 293
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.26377 1794.1 235
Replication protein A 14 kDa subunit RPA3 Tbio Non-IDG -1.85941 67.1 171
Cyclin-O CCNO Tbio Non-IDG -1.55274 37.4 183
DNA excision repair protein ERCC-6 ERCC6 Tbio Non-IDG -2.31776 361.5 163
E3 ubiquitin-protein ligase HUWE1 HUWE1 Tbio Enzyme -2.11897 123.4 121