Development Level

Tbio 4 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
decreased bone mineral content 1 | 151
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased hematocrit 1 | 46
pale yolk sac 1 | 25
pallor 1 | 34

Disease

Carcinoma 3 | 11,493
adult high grade glioma 3 | 3,801
cutaneous lupus erythematosus 3 | 1,057
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
Astrocytoma, Pilocytic 2 | 3,081
Cancer 2 | 2,499
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
dermatomyositis 2 | 966
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
juvenile dermatomyositis 2 | 1,187
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
AICARDI-GOUTIERES SYNDROME 1 1 | 5
AICARDI-GOUTIERES SYNDROME 6 1 | 1
Acquired immunodeficiency syndrome 1 | 197
Aicardi-Goutieres syndrome 1 | 19
Amyotrophic lateral sclerosis 1 | 451
Arhinencephaly 1 | 5
Autosomal recessive predisposition 1 | 1,442
Bipolar Disorder 1 | 666
Breast Neoplasms 1 | 445
Breast cancer 1 | 3,578
Chronic Lymphocytic Leukemia 1 | 262
Chronic obstructive pulmonary disease 1 | 184
Cognitive delay 1 | 608
Coloboma of eyelid 1 | 15
Contact Dermatitis 1 | 81
Dowling-Degos disease 1 | 7
Duchenne muscular dystrophy 1 | 601
Dyschromatosis symmetrica hereditaria 1 | 4
Dyschromatosis symmetrica hereditaria 1 1 | 1
Dyschromatosis universalis hereditaria 1 | 6
Dystonia Musculorum Deformans 1 | 5
Global developmental delay 1 | 608
Hemiplegia and hemiparesis 1 | 38
Hepatitis B 1 | 108
Human immunodeficiency virus infectious disease 1 | 138
Hyperpigmented/hypopigmented macules 1 | 1
Infantile onset 1 | 238
Kidney cancer 1 | 2,613
Loss of ability to walk 1 | 3
Loss of speech 1 | 16
Macular hyperpigmentation 1 | 1
Macular hypopigmentation 1 | 1
Macule 1 | 19
Mental and motor retardation 1 | 608
Multiple myeloma 1 | 1,332
Muscle Rigidity 1 | 49
Muscle Spasticity 1 | 195
Polycystic ovary syndrome 1 | 360
Porencephaly 1 | 20
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
Psychotic Disorders 1 | 151
Reticulate acropigmentation of Kitamura 1 | 9
STRIATONIGRAL DEGENERATION, INFANTILE (disorder) 1 | 3
Schizophrenia 1 | 1,160
Spindle cell hemangioma 1 | 16
Steatitis 1 | 2
Striatonigral Degeneration, Infantile 1 | 4
Symmetrical dyschromatosis of extremities 1 | 1
Theileriasis 1 | 13
Tremor 1 | 113
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 922
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
astrocytic glioma 1 | 2,597
breast carcinoma 1 | 1,638
chronic kidney disease 1 | 90
cystic fibrosis 1 | 1,696
ependymoma 1 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
lung adenocarcinoma 1 | 2,716
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
pituitary cancer 1 | 1,972
primary Sjogren syndrome 1 | 735
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Enzyme 2 | 4,145
Non-IDG 2 | 12,091

GO Process

base conversion or substitutio... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G Tbio Non-IDG -2.78510 662.2 477
Double-stranded RNA-specific editase 1 ADARB1 Tbio Enzyme -2.08959 118.0 103
DNA dC->dU-editing enzyme APOBEC-3F APOBEC3F Tbio Non-IDG -1.98109 90.7 136
Double-stranded RNA-specific adenosine deaminase ADAR Tbio Enzyme -2.87338 784.2 197