Development Level

Tbio 117 | 10,625
Tchem 28 | 1,890
Tdark 9 | 7,003
Tclin 3 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 11 | 633
decreased bone mineral content 4 | 157
decreased circulating serum al... 4 | 79
decreased lean body mass 4 | 195
abnormal bone structure 3 | 131
decreased body weight 3 | 174
decreased circulating total pr... 3 | 41
decreased total body fat amoun... 3 | 186
increased circulating alkaline... 3 | 119
increased circulating iron lev... 3 | 25
limb grasping 3 | 35
prenatal lethality prior to he... 3 | 64
preweaning lethality, incomple... 3 | 260
short tibia 3 | 82
abnormal behavior 2 | 226
abnormal gait 2 | 51
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating alkaline... 2 | 41
decreased circulating choleste... 2 | 85
decreased eosinophil cell numb... 2 | 41
embryonic lethality prior to t... 2 | 187
impaired glucose tolerance 2 | 52
increased fasted circulating g... 2 | 68
increased mean corpuscular hem... 2 | 93
male infertility 2 | 62
tremors 2 | 34
abnormal anxiety-related respo... 1 | 1
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal heart left ventricle ... 1 | 20
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal nail morphology 1 | 7
abnormal placenta size 1 | 10
abnormal skin coloration 1 | 18
abnormal social/conspecific in... 1 | 3
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal vocalization 1 | 21
cataract 1 | 26
corneal opacity 1 | 25
decreased NK T cell number 1 | 28
decreased circulating LDL chol... 1 | 37
decreased circulating chloride... 1 | 32
decreased circulating free fat... 1 | 39
decreased circulating insulin ... 1 | 75
decreased circulating iron lev... 1 | 25
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased kidney weight 1 | 7
decreased lactate dehydrogenas... 1 | 14
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased pulmonary respirator... 1 | 4
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased vertical activity 1 | 22
edema 1 | 11
enlarged adrenal glands 1 | 3
enlarged kidney 1 | 7
enlarged stomach 1 | 2
enlarged uterus 1 | 3
female infertility 1 | 34
hemorrhage 1 | 12
hydrometra 1 | 13
hyperactivity 1 | 108
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating bilirubi... 1 | 16
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
irregularly shaped pupil 1 | 7
lethargy 1 | 5
oligodactyly 1 | 14
polycystic kidney 1 | 9
small testis 1 | 37
small thymus 1 | 11
thrombocytosis 1 | 23

Disease

ovarian cancer 84 | 8,484
glioblastoma 79 | 5,572
medulloblastoma, large-cell 75 | 6,234
osteosarcoma 75 | 7,933
psoriasis 75 | 6,685
lung cancer 62 | 4,466
atypical teratoid / rhabdoid tumor 56 | 4,369
oligodendroglioma 55 | 2,849
Carcinoma 52 | 2,147
pilocytic astrocytoma 51 | 3,086
Breast cancer 50 | 3,094
Cancer 50 | 2,346
malignant mesothelioma 46 | 3,162
lung carcinoma 45 | 2,844
pediatric high grade glioma 45 | 2,712
invasive ductal carcinoma 39 | 2,950
non-small cell lung cancer 39 | 2,798
group 4 medulloblastoma 38 | 1,875
lung adenocarcinoma 38 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,289
primitive neuroectodermal tumor 36 | 3,031
pancreatic cancer 35 | 2,300
astrocytic glioma 34 | 2,241
subependymal giant cell astrocytoma 34 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,988
pituitary cancer 32 | 1,972
cystic fibrosis 30 | 1,665
sonic hedgehog group medulloblastoma 29 | 1,482
ependymoma 27 | 2,514
group 3 medulloblastoma 27 | 2,254
interstitial cystitis 27 | 2,299
posterior fossa group A ependymoma 27 | 1,511
breast carcinoma 26 | 1,614
colon cancer 25 | 1,475
Pick disease 24 | 1,893
adult high grade glioma 23 | 2,148
astrocytoma 23 | 1,493
ductal carcinoma in situ 22 | 1,745
primary pancreatic ductal adenocarcinoma 22 | 1,271
ulcerative colitis 21 | 2,087
posterior fossa group B ependymoma 20 | 1,530
cutaneous lupus erythematosus 19 | 1,056
Schizophrenia 17 | 501
atypical teratoid/rhabdoid tumor 17 | 1,095
Autistic Disorder 16 | 320
Rheumatoid Arthritis 16 | 1,160
adrenocortical carcinoma 16 | 1,427
medulloblastoma 16 | 1,524
Alzheimer's disease 15 | 644
Intellectual disability 15 | 573
juvenile dermatomyositis 14 | 1,189
Epilepsy 13 | 346
Atopic dermatitis 12 | 944
Stomach Neoplasms 10 | 282
diabetes mellitus 10 | 1,663
esophageal adenocarcinoma 10 | 737
interstitial lung disease 10 | 291
non-small cell lung carcinoma 10 | 413
spina bifida 10 | 1,064
Duchenne muscular dystrophy 9 | 602
Obesity 9 | 616
Parkinson's disease 9 | 364
Prostatic Neoplasms 9 | 471
aldosterone-producing adenoma 9 | 664
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
Amyotrophic Lateral Sclerosis 8 | 431
Bipolar Disorder 8 | 266
Cleft palate 8 | 125
Endometriosis 8 | 535
Mammary Neoplasms 8 | 410
Neuropathy 8 | 210
fibroadenoma 8 | 557
nasopharyngeal carcinoma 8 | 1,056
tuberculosis and treatment for 6 months 8 | 686
Craniofacial Abnormalities 7 | 147
Down syndrome 7 | 548
Kidney cancer 7 | 118
Multiple Sclerosis 7 | 498
Neoplasm Invasiveness 7 | 127
Waldenstrons macroglobulinemia 7 | 765
acute quadriplegic myopathy 7 | 1,157
glioblastoma multiforme 7 | 347
progressive supranuclear palsy 7 | 674
tuberculosis 7 | 1,557
Acquired metabolic disease 6 | 267
Cleft Lip 6 | 91
Lissencephaly 6 | 61
Liver carcinoma 6 | 217
Lung Neoplasms 6 | 171
Neuroblastoma 6 | 78
Toxic encephalopathy 6 | 131
Vascular disease 6 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
chronic rhinosinusitis 6 | 512
dermatomyositis 6 | 933
facioscapulohumeral dystrophy 6 | 286
gastric carcinoma 6 | 832
hereditary spastic paraplegia 6 | 313
primary Sjogren syndrome 6 | 789

Tissue

Nervous System 154 | 18,561
Digestive Tract 153 | 18,473
Endocrine System 153 | 18,512
Female tissues 153 | 18,647
Urinary Tract 153 | 18,444
Liver and Pancreas 152 | 18,136
Skin and soft tissues 152 | 18,115
Cardiovascular System 150 | 17,958
Male tissues 149 | 17,969
Blood and immune system 146 | 17,995
Respiratory system 146 | 17,484

Target Family

Non-IDG 97 | 11,971
Transcription Factor 22 | 1,400
Enzyme 20 | 4,146
Kinase 15 | 634
Ion Channel 1 | 341
Nuclear Receptor 1 | 48
oGPCR 1 | 421

GO Process

axon guidance 157 | 157
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Laminin subunit alpha-2 LAMA2 Tbio Non-IDG -2.48634 321.9 131
C-Jun-amino-terminal kinase-interacting protein 3 MAPK8IP3 Tbio Enzyme -1.63360 51.0 128
LIM/homeobox protein Lhx2 LHX2 Tbio Transcription Factor -1.89097 87.7 161
Isoprenoid synthase domain-containing protein ISPD Tbio Enzyme -2.11906 132.4 54
Zinc finger protein 280D ZNF280D Tdark Transcription Factor 0.41 0.29 43
Group 10 secretory phospholipase A2 PLA2G10 Tchem Enzyme -2.39398 288.4 31
Slit homolog 1 protein SLIT1 Tbio Non-IDG -1.66562 42.1 104
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.17963 1388.1 188
Anosmin-1 ANOS1 Tbio Non-IDG -2.61285 410.8 140