Development Level

Tbio 83 | 11,651
Tchem 17 | 1,388
Tdark 7 | 6,593
Tclin 3 | 612

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal behavior 4 | 298
preweaning lethality, incomple... 4 | 499
decreased red blood cell distr... 3 | 41
increased lean body mass 3 | 172
abnormal bone structure 2 | 187
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating aspartat... 2 | 34
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased grip strength 2 | 116
embryonic lethality prior to t... 2 | 278
increased circulating alkaline... 2 | 122
increased grip strength 2 | 41
increased mean corpuscular vol... 2 | 92
long tibia 2 | 25
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal optic disc morphology 1 | 10
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating lactate ... 1 | 3
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
increased B cell number 1 | 9
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
polycystic kidney 1 | 15
premature death 1 | 5
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 69 | 11,493
ovarian cancer 68 | 8,520
osteosarcoma 55 | 7,950
medulloblastoma, large-cell 43 | 6,241
glioblastoma 35 | 5,792
atypical teratoid / rhabdoid tumor 31 | 5,112
lung cancer 31 | 4,740
psoriasis 31 | 6,694
Cancer 29 | 2,499
ependymoma 26 | 4,679
Neurodegenerative disease 25 | 414
adult high grade glioma 21 | 3,801
Multiple myeloma 19 | 1,332
astrocytic glioma 18 | 2,597
diabetes mellitus 17 | 1,728
group 3 medulloblastoma 17 | 4,104
group 4 medulloblastoma 17 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
lung carcinoma 16 | 2,843
malignant mesothelioma 16 | 3,232
primitive neuroectodermal tumor 16 | 3,035
Astrocytoma, Pilocytic 15 | 3,081
Breast cancer 15 | 3,578
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
tuberculosis 15 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
lung adenocarcinoma 14 | 2,716
subependymal giant cell astrocytoma 14 | 2,287
Kidney cancer 13 | 2,613
oligodendroglioma 13 | 2,850
pancreatic cancer 13 | 2,398
astrocytoma 12 | 1,146
breast carcinoma 12 | 1,638
dermatomyositis 12 | 966
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
invasive ductal carcinoma 12 | 2,951
non-small cell lung cancer 12 | 2,890
Autosomal recessive predisposition 11 | 1,442
Schizophrenia 11 | 1,160
acute quadriplegic myopathy 11 | 1,158
ulcerative colitis 11 | 1,819
Pick disease 10 | 1,894
Rheumatoid arthritis 10 | 1,191
Waldenstrons macroglobulinemia 10 | 765
interstitial cystitis 10 | 2,312
spina bifida 10 | 1,074
Alzheimer's disease 9 | 658
Amyotrophic lateral sclerosis 9 | 451
Dysarthria 9 | 192
cutaneous lupus erythematosus 9 | 1,057
ductal carcinoma in situ 9 | 1,745
pituitary cancer 9 | 1,972
Fatigue 8 | 182
Frontotemporal dementia 8 | 51
Vascular disease 8 | 319
active Crohn's disease 8 | 922
hepatocellular carcinoma 8 | 547
medulloblastoma 8 | 720
primary pancreatic ductal adenocarcinoma 8 | 1,109
Anxiety 7 | 136
Anxiety disease 7 | 113
Deglutition Disorders 7 | 132
Dementia 7 | 175
Depressive disorder 7 | 409
Dystonia 7 | 164
Epilepsy 7 | 792
Muscle Spasticity 7 | 195
Nerve Degeneration 7 | 121
Parkinson's disease 7 | 392
adrenocortical carcinoma 7 | 1,428
juvenile dermatomyositis 7 | 1,187
progressive supranuclear palsy 7 | 676
Cerebral atrophy 6 | 178
Down syndrome 6 | 499
Dystonic disease 6 | 106
Glaucoma 6 | 239
Mood swings 6 | 77
Neuro-degenerative disease 6 | 43
Neurodegenerative Disorders 6 | 79
Neurogenic Muscular Atrophy 6 | 139
Neurogenic muscle atrophy, especially in the lower limbs 6 | 139
Renal Cell Carcinoma 6 | 214
Respiratory Failure 6 | 104
Skeletal muscle atrophy 6 | 139
esophageal adenocarcinoma 6 | 737
mucosa-associated lymphoid tissue lymphoma 6 | 484
muscle degeneration 6 | 139
non primary Sjogren syndrome sicca 6 | 891
pediatric high grade glioma 6 | 1,064
Atopic dermatitis 5 | 952
Dyspnea 5 | 76
Generalized muscle weakness 5 | 57
Huntington's disease 5 | 76
Paralysed 5 | 42
Systemic lupus erythematosus 5 | 194
Vici syndrome 5 | 14
active ulcerative colitis 5 | 764
acute myeloid leukemia 5 | 783
colon cancer 5 | 1,478
primary Sjogren syndrome 5 | 735

Tissue

Blood and immune system 109 | 16,909
Digestive Tract 109 | 17,369
Endocrine System 109 | 18,159
Female tissues 109 | 17,400
Liver and Pancreas 109 | 16,750
Male tissues 109 | 17,142
Nervous System 109 | 16,725
Respiratory system 109 | 16,393
Skin and soft tissues 109 | 17,230
Urinary Tract 109 | 16,678
Cardiovascular System 105 | 15,192

Target Family

Non-IDG 65 | 12,091
Enzyme 28 | 4,145
Kinase 8 | 634
Transcription Factor 6 | 1,400
Epigenetic 3 | 242

GO Process

autophagy 110 | 110
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
PHD finger protein 23 PHF23 Tbio Epigenetic -0.51820 3.24 45
Transmembrane protein 208 TMEM208 Tdark Non-IDG -0.09691 1.33 18
Sequestosome-1 SQSTM1 Tbio Non-IDG -2.78728 635.1 766
Vacuolar protein sorting-associated protein 51 homolog VPS51 Tbio Non-IDG -2.64126 419.3 58
WD repeat domain phosphoinositide-interacting protein 1 WIPI1 Tbio Non-IDG -1.64159 43.5 192
Tectonin beta-propeller repeat-containing protein 2 TECPR2 Tdark Non-IDG -0.62595 4.65 19
Death-associated protein 1 DAP Tbio Non-IDG -2.28005 160.9 183
Phosphatidylinositol 3-kinase catalytic subunit type 3 PIK3C3 Tchem Kinase -2.33238 204.8 739
E3 ubiquitin-protein ligase TRIM17 TRIM17 Tbio Enzyme -1.93679 76.0 118
Tyrosine-protein phosphatase non-receptor type 22 PTPN22 Tchem Enzyme -2.70715 543.9 211