Development Level

Tbio 93 | 10,625
Tchem 16 | 1,890
Tdark 9 | 7,003
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 10 | 633
abnormal behavior 3 | 226
decreased bone mineral content 3 | 157
decreased lean body mass 3 | 195
embryonic lethality prior to o... 3 | 148
hypoactivity 3 | 89
increased bone mineral content 3 | 92
increased or absent threshold ... 3 | 128
abnormal body wall morphology 2 | 7
abnormal bone structure 2 | 131
decreased rib number 2 | 59
embryonic lethality prior to t... 2 | 187
increased body length 2 | 20
increased grip strength 2 | 83
preweaning lethality, incomple... 2 | 260
abnormal bone mineralization 1 | 55
abnormal coat appearance 1 | 25
abnormal coping response 1 | 12
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal eye posterior chamber... 1 | 3
abnormal kidney morphology 1 | 30
abnormal retinal inner nuclear... 1 | 5
abnormal skin morphology 1 | 23
abnormal testis morphology 1 | 30
abnormal vertebrae morphology 1 | 14
decreased IgG1 level 1 | 4
decreased NK T cell number 1 | 28
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 27
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased prepulse inhibition 1 | 52
decreased red blood cell distr... 1 | 11
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
enlarged epididymis 1 | 27
enlarged spleen 1 | 26
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased bone mineral density 1 | 52
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating glucose ... 1 | 16
increased effector memory CD4-... 1 | 15
increased fasted circulating g... 1 | 68
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
increased rib number 1 | 41
limb grasping 1 | 35
male infertility 1 | 62
polycystic kidney 1 | 9
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
protruding tongue 1 | 1
short tibia 1 | 82
shortened RR interval 1 | 19
straub tail 1 | 26
vertebral fusion 1 | 23

Disease

ovarian cancer 79 | 8,484
osteosarcoma 55 | 7,933
medulloblastoma, large-cell 41 | 6,234
glioblastoma 37 | 5,572
psoriasis 37 | 6,685
atypical teratoid / rhabdoid tumor 28 | 4,369
lung cancer 26 | 4,466
Cancer 25 | 2,346
Multiple myeloma 24 | 1,327
Neurodegenerative disease 22 | 383
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,795
Breast cancer 16 | 3,094
diabetes mellitus 16 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
pilocytic astrocytoma 16 | 3,086
ependymoma 15 | 2,514
group 4 medulloblastoma 15 | 1,875
lung adenocarcinoma 15 | 2,713
malignant mesothelioma 15 | 3,162
medulloblastoma 15 | 1,524
pediatric high grade glioma 15 | 2,712
primitive neuroectodermal tumor 15 | 3,031
tuberculosis 15 | 1,557
astrocytoma 14 | 1,493
dermatomyositis 14 | 933
subependymal giant cell astrocytoma 14 | 2,287
ulcerative colitis 14 | 2,087
astrocytic glioma 13 | 2,241
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,956
invasive ductal carcinoma 13 | 2,950
lung carcinoma 13 | 2,844
oligodendroglioma 13 | 2,849
pancreatic cancer 13 | 2,300
Waldenstrons macroglobulinemia 12 | 765
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,289
posterior fossa group A ependymoma 12 | 1,511
Pick disease 11 | 1,893
acute quadriplegic myopathy 11 | 1,157
adult high grade glioma 11 | 2,148
Carcinoma 10 | 2,147
breast carcinoma 10 | 1,614
interstitial cystitis 10 | 2,299
cutaneous lupus erythematosus 9 | 1,056
non-small cell lung cancer 9 | 2,798
pituitary cancer 9 | 1,972
spina bifida 9 | 1,064
Alzheimer's disease 8 | 644
active Crohn's disease 8 | 918
atypical teratoid/rhabdoid tumor 8 | 1,095
group 3 medulloblastoma 8 | 2,254
juvenile dermatomyositis 8 | 1,189
primary pancreatic ductal adenocarcinoma 8 | 1,271
progressive supranuclear palsy 8 | 674
tuberculosis and treatment for 6 months 8 | 686
Dementia 7 | 129
Down syndrome 7 | 548
Rheumatoid Arthritis 7 | 1,160
ductal carcinoma in situ 7 | 1,745
non primary Sjogren syndrome sicca 7 | 840
Obesity 6 | 616
Parkinson's disease 6 | 364
Vascular disease 6 | 281
adrenocortical carcinoma 6 | 1,427
esophageal adenocarcinoma 6 | 737
hepatocellular carcinoma 6 | 532
pancreatic carcinoma 6 | 567
posterior fossa group B ependymoma 6 | 1,530
primary Sjogren syndrome 6 | 789
Amyotrophic Lateral Sclerosis 5 | 431
Crohn's disease 5 | 304
Frontotemporal dementia 5 | 41
IGA Glomerulonephritis 5 | 454
Vici syndrome 5 | 16
aldosterone-producing adenoma 5 | 664
cystic fibrosis 5 | 1,665
hereditary spastic paraplegia 5 | 313
mucosa-associated lymphoid tissue lymphoma 5 | 480
sonic hedgehog group medulloblastoma 5 | 1,482
systemic lupus erythematosus 5 | 156
Atopic dermatitis 4 | 944
Duchenne muscular dystrophy 4 | 602
Dystonia 4 | 77
Inflammatory Bowel Diseases 4 | 87
Renal Cell Carcinoma 4 | 199
acute myeloid leukemia 4 | 780
alcohol-related neurodevelopmental disorder 4 | 11
chronic lymphosyte leukemia 4 | 232
fibroadenoma 4 | 557
gastric cancer 4 | 430
tuberculosis and treatment for 3 months 4 | 327
Becker muscular dystrophy 3 | 187
Epilepsy 3 | 346
Gaucher disease type 1 3 | 171
Mammary Neoplasms 3 | 410
Myocardial Ischemia 3 | 169
Necrosis 3 | 51
Schizophrenia 3 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
colon cancer 3 | 1,475
nasopharyngeal carcinoma 3 | 1,056

Tissue

Digestive Tract 119 | 18,473
Endocrine System 119 | 18,512
Female tissues 119 | 18,647
Liver and Pancreas 119 | 18,136
Nervous System 119 | 18,561
Skin and soft tissues 119 | 18,115
Urinary Tract 119 | 18,444
Blood and immune system 118 | 17,995
Cardiovascular System 118 | 17,958
Male tissues 118 | 17,969
Respiratory system 118 | 17,484

Target Family

Non-IDG 81 | 11,971
Enzyme 24 | 4,146
Kinase 7 | 634
Transcription Factor 5 | 1,400
Epigenetic 2 | 242

GO Process

autophagy 119 | 119
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Charged multivesicular body protein 2b CHMP2B Tbio Non-IDG -1.65708 53.0 166
Tectonin beta-propeller repeat-containing protein 2 TECPR2 Tdark Non-IDG -0.62839 4.84 6
Sestrin-2 SESN2 Tbio Non-IDG -1.73062 73.0 151
Ras-related protein Rab-33B RAB33B Tbio Enzyme -0.75609 7.38 45
Serine/threonine-protein kinase ULK2 ULK2 Tchem Kinase -1.07146 10.6 355
Ubiquitin-like-conjugating enzyme ATG10 ATG10 Tbio Non-IDG -1.17565 13.8 187
Ras-related protein Rab-1B RAB1B Tbio Enzyme 36.3 104
Toll-interacting protein TOLLIP Tbio Non-IDG -1.78649 72.7 353
Tyrosine-protein kinase ABL1 ABL1 Tclin Kinase -3.47805 3222.2 1533
Ras-related protein Rab-1A RAB1A Tbio Enzyme -2.35747 242.5 102