Development Level

Tbio 9 | 11,445

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

increased or absent threshold ... 2 | 101
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal hindbrain morphology 1 | 10
abnormal locomotor activation 1 | 16
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
absent pinna reflex 1 | 23
decreased body weight 1 | 161
decreased lean body mass 1 | 135
embryonic growth retardation 1 | 106
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 6 | 11,493
Nonsyndromic deafness 5 | 142
ovarian cancer 5 | 8,520
osteosarcoma 4 | 7,950
Autosomal recessive predisposition 3 | 1,442
breast carcinoma 3 | 1,638
ependymoma 3 | 4,679
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Blindness 2 | 88
Cancer 2 | 2,499
Hodgkin's lymphoma, nodular sclerosis 2 | 22
Kidney cancer 2 | 2,613
Retinitis Pigmentosa 2 | 226
Schizophrenia 2 | 1,160
Sensorineural Hearing Loss (disorder) 2 | 284
Sensorineural hearing loss 2 | 106
Usher Syndrome, Type II 2 | 5
Usher syndrome 2 | 32
Usher syndrome type 2 2 | 5
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Abnormal vision 1 | 52
Abnormality of cochlea 1 | 6
Absent vestibular function 1 | 2
Amyotrophic lateral sclerosis type 1 1 | 23
CATSPER-Related Male Infertility 1 | 3
Carcinoma, Ductal, Breast 1 | 11
Cell Transformation, Neoplastic 1 | 97
Congenital dyserythropoietic anemia 1 | 18
Deafness, Autosomal Recessive 67 1 | 2
Deafness, Sensorineural, And Male Infertility 1 | 2
Deafness-Infertility Syndrome 1 | 2
Degeneration of anterior horn cells 1 | 7
Diabetes Mellitus, Experimental 1 | 108
Diabetic retinopathy 1 | 56
Dyspnea 1 | 76
Fatigable weakness of respiratory muscles 1 | 28
Fatty Liver 1 | 70
Gait Disorders, Neurologic 1 | 3
Generalized osteopenia 1 | 99
Glioma 1 | 74
Hearing Loss 1 | 17
Hemianopsia 1 | 15
Hepatitis, Chronic 1 | 23
High-grade hypermetropia 1 | 24
Hyperthyroidism 1 | 53
Hypotension 1 | 82
Ischemia 1 | 28
Kidney Calculi 1 | 7
Koolen de Vries syndrome 1 | 18
Lateral sclerosis 1 | 15
Macular degeneration 1 | 65
Muscle Cramp 1 | 55
Muscular fasciculation 1 | 22
Neoplastic Cell Transformation 1 | 89
Nephrosis 1 | 21
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Osteopenia 1 | 99
Ovarian Neoplasms 1 | 102
Pain 1 | 103
Paralysed 1 | 42
Pigmentary iris degeneration 1 | 20
Primary Lateral Sclerosis, Juvenile 1 | 3
Pseudobulbar palsy 1 | 11
Pulmonary Fibrosis 1 | 106
Radiation Injuries, Experimental 1 | 11
Retinal blind spot 1 | 11
Scotoma 1 | 22
Scrapie 1 | 17
Sensorineural hearing loss, bilateral 1 | 18
Sleep Apnea Syndromes 1 | 13
Spermatogenic Failure 7 1 | 3
Spinal Cord Injuries 1 | 8
Spinal cord disease 1 | 25
Usher Syndrome, Type 1 1 | 7
Usher Syndrome, Type I 1 | 6
Usher Syndromes 1 | 2
Usher syndrome, type 1B 1 | 2
Vestibular hypofunction 1 | 7
Weight Loss 1 | 24
Xerostomia 1 | 42
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Skin and soft tissues 9 | 17,230
Cardiovascular System 8 | 15,192
Liver and Pancreas 8 | 16,750
Respiratory system 8 | 16,393
Urinary Tract 8 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 1 | 4,145
Ion Channel 1 | 344
Transporter 1 | 473

GO Process

auditory receptor cell stereoc... 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Stereocilin STRC Tbio Non-IDG -1.30533 34.5 8
PDZ domain-containing protein 7 PDZD7 Tbio Non-IDG -0.78604 7.25 45
LHFPL tetraspan subfamily member 5 protein LHFPL5 Tbio Non-IDG -2.00814 98.6 64
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 SLC9A3R1 Tbio Transporter -3.11679 1295.9 249
Chloride intracellular channel protein 5 CLIC5 Tbio Ion Channel -0.97229 9.78 179
Superoxide dismutase [Cu-Zn] SOD1 Tbio Enzyme -3.30643 1972.1 1103
Protein scribble homolog SCRIB Tbio Non-IDG -1.79333 61.7 94
Protein transport protein Sec24B SEC24B Tbio Non-IDG -1.80480 64.6 17