Development Level

Tbio 10 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal pericardium morpholog... 1 | 26
embryonic lethality prior to t... 1 | 278
increased heart rate variabili... 1 | 7
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 9 | 11,493
ovarian cancer 8 | 8,520
Congenital heart disease 7 | 93
Breast cancer 6 | 3,578
glioblastoma 6 | 5,792
lung cancer 6 | 4,740
lung carcinoma 6 | 2,843
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
Cardiomyopathy 5 | 116
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
psoriasis 5 | 6,694
Brachydactyly 4 | 156
Broad forehead 4 | 59
Cancer 4 | 2,499
Cryptorchidism 4 | 296
Holt-Oram syndrome 4 | 12
Long narrow head 4 | 75
Narrow cranium shape 4 | 75
Narrow head shape 4 | 75
Narrow skull shape 4 | 75
Thin lips 4 | 49
Turridolichocephaly 4 | 75
interstitial cystitis 4 | 2,312
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 3 | 21
Abnormal nasal morphology 3 | 16
Astrocytoma, Pilocytic 3 | 3,081
Atrial Fibrillation 3 | 124
Atrial Septal Defects 3 | 85
Atrial heart septal defect 3 | 18
Bilateral fifth finger clinodactyly 3 | 110
Breast Neoplasms 3 | 445
Byzanthine arch palate 3 | 194
Cardiomegaly 3 | 116
Curvature of little finger 3 | 110
Exophthalmos 3 | 112
Familial atrial fibrillation 3 | 23
Fetal Growth Retardation 3 | 189
Heart disease 3 | 306
Hernia, Inguinal 3 | 89
Hypertensive disease 3 | 292
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Kidney cancer 3 | 2,613
Mammary Neoplasms 3 | 425
Osteoporosis 3 | 363
Ostium secundum atrial septal defect 3 | 9
Preauricular Fistulae, Congenital 3 | 27
Preauricular dimple 3 | 27
Preauricular sinus 3 | 27
Prominent eyes 3 | 96
Prominent globes 3 | 96
Protruding eyes 3 | 96
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
Tetralogy of Fallot 3 | 63
Umbilical hernia 3 | 93
Underdeveloped brows 3 | 38
Underdeveloped supraorbital ridges 3 | 38
Ventricular Septal Defects 3 | 119
adult high grade glioma 3 | 3,801
cystic fibrosis 3 | 1,696
juvenile dermatomyositis 3 | 1,187
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
primary pancreatic ductal adenocarcinoma 3 | 1,109
Acquired scoliosis 2 | 281
Alagille syndrome 2 | 15
Atrioventricular block 2 | 35
Broad thumbs 2 | 28
Coarse facial features 2 | 108
Congenital Epicanthus 2 | 177
Curvature of spine 2 | 282
Discordant ventriculoarterial connection 2 | 17
Dull intelligence 2 | 645
Generalized hirsutism 2 | 36
Glaucoma 2 | 239
Hypertension 2 | 396
Joint hyperflexibility 2 | 78
Lung Neoplasms 2 | 232
Myocardial Infarction 2 | 151
Penile hypospadias 2 | 106
Polycystic ovary syndrome 2 | 360
Right atrial isomerism 2 | 29
Skin cancer 2 | 469
Thickened facial skin with coarse facial features 2 | 108
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
periodontitis 2 | 293
pituitary cancer 2 | 1,972
urothelial carcinoma 2 | 318
ventricular septal defect 2 | 20

Tissue

Female tissues 13 | 17,400
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Endocrine System 12 | 18,159
Liver and Pancreas 12 | 16,750
Urinary Tract 12 | 16,678
Digestive Tract 11 | 17,369
Male tissues 11 | 17,142
Respiratory system 11 | 16,393
Skin and soft tissues 10 | 17,230
Nervous System 9 | 16,725

Target Family

Transcription Factor 7 | 1,400
Non-IDG 4 | 12,091
GPCR 1 | 408
Kinase 1 | 634

GO Process

atrial septum morphogenesis 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurogenic locus notch homolog protein 2 NOTCH2 Tchem Non-IDG -2.52434 287.2 451
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Transcription factor GATA-4 GATA4 Tbio Transcription Factor -2.90202 763.9 496
Protein CYR61 CYR61 Tbio Non-IDG -2.43164 320.5 423
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Zinc finger protein ZFPM1 ZFPM1 Tbio Transcription Factor -2.52665 326.6 82
Hairy/enhancer-of-split related with YRPW motif protein 2 HEY2 Tbio Transcription Factor -2.43307 261.2 173
T-box transcription factor TBX5 TBX5 Tbio Transcription Factor -2.38269 244.4 198
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382