Development Level

Tbio 7 | 10,625

IMPC Term

preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal optic disc morphology 1 | 10
abnormal tooth morphology 1 | 24
corneal opacity 1 | 25
decreased circulating creatini... 1 | 31
enlarged heart 1 | 111
improved glucose tolerance 1 | 56
increased grip strength 1 | 83
increased heart weight 1 | 37
irregularly shaped pupil 1 | 7
prenatal lethality 1 | 16
small testis 1 | 37

Disease

Cancer 4 | 2,346
interstitial cystitis 3 | 2,299
lung carcinoma 3 | 2,844
medulloblastoma, large-cell 3 | 6,234
osteosarcoma 3 | 7,933
pancreatic cancer 3 | 2,300
psoriasis 3 | 6,685
Carcinoma 2 | 2,147
Congenital Heart Defects 2 | 37
Congenital heart disease 2 | 63
Hereditary hemorrhagic telangiectasia 2 | 14
Type 2 diabetes mellitus 2 | 192
colon cancer 2 | 1,475
glioblastoma 2 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
lung cancer 2 | 4,473
medulloblastoma 2 | 1,524
non-small cell lung cancer 2 | 2,798
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 2,087
Acquired metabolic disease 1 | 267
Angiodysplasia 1 | 5
Angiokeratoma 1 | 9
Ankylosis 1 | 25
Arteriovenous malformation 1 | 8
Atrial Septal Defects 1 | 2
Atrial heart septal defect 1 | 15
Atrial septal defect 3 1 | 1
Autistic Disorder 1 | 320
Axenfeld anomaly (disorder) 1 | 2
Axenfeld-Rieger Syndrome, Type 1 1 | 3
Axenfeld-Rieger syndrome 1 | 11
Axenfeld-Rieger syndrome 1 1 | 1
Brachydactyly 1 | 52
COPD 1 | 116
Cardiomyopathy 1 | 110
Cardiomyopathy, Dilated 1 | 47
Cardiomyopathy, Dilated, 1EE 1 | 1
Cardiomyopathy, Familial Hypertrophic, 1 1 | 6
Cardiomyopathy, Familial Hypertrophic, 1 (disorder) 1 | 10
Cardiomyopathy, Familial Hypertrophic, 14 1 | 1
Cardiomyopathy, Hypertrophic, Familial 1 | 21
Cardiomyopathy, dilated 1EE 1 | 1
Cardiomyopathy, familial hypertrophic 14 1 | 1
Cleft palate 1 | 125
Cogan-Reese syndrome 1 | 2
Connective tissue disease 1 | 59
Corneal disease 1 | 32
Craniofacial Abnormalities 1 | 147
Dilated cardiomyopathy 1 | 51
Distal arthrogryposis 1 | 45
Dupuytren Contracture 1 | 5
Esophageal atresia 1 | 25
Familial isolated dilated cardiomyopathy 1 | 41
Fibrodysplasia ossificans progressiva 1 | 17
Frontotemporal dementia 1 | 47
Heart conduction disease 1 | 65
Heart, malformation of 1 | 3
Hyperopia 1 | 33
Hypertrophic Cardiomyopathy 1 | 56
IRIDOGONIODYSGENESIS, TYPE 2 1 | 1
Iridogoniodysgenesis 2 1 | 1
Iridogoniodysgenesis syndrome 1 | 8
Iridogoniodysgenesis, dominant type 1 | 1
Juvenile polyposis syndrome 1 | 7
Lymphangioma 1 | 7
Lymphedema 1 | 26
Multiple synostoses syndrome 1 | 8
Myocardial Infarction 1 | 126
Myopathy 1 | 128
Neoplasm Metastasis 1 | 138
Ophthalmoplegia 1 | 18
Osteoarthritis 1 | 96
Osteoporosis 1 | 259
Ostium secundum atrial septal defect 1 | 8
Otosclerosis 1 | 13
Persistent hyperplastic primary vitreous 1 | 20
Peters anomaly 1 | 4
Pituitary hypoplasia 1 | 15
Proximal symphalangism 1 | 6
RESTING HEART RATE 1 | 8
Rieger syndrome 1 | 2
Ring dermoid of cornea 1 | 1
SICK SINUS SYNDROME 3, SUSCEPTIBILITY TO 1 | 1
Sclerosteosis 1 | 9
Severe Combined Immunodeficiency 1 | 46
Sick sinus syndrome 1 | 14
Sick sinus syndrome 3 1 | 1
Telangiectasia, Hereditary Hemorrhagic, of Rendu, Osler, and Weber 1 | 1
Telangiectasia, hereditary hemorrhagic, 1 1 | 1
Telangiectasis 1 | 20
Tooth Abnormalities 1 | 10
Tooth agenesis 1 | 38
Type VI Ehlers-Danlos syndrome 1 | 4
Uterine Cervical Neoplasm 1 | 21
Visceral heterotaxy 1 | 12
permanent atrial fibrillation 1 | 44
pre-eclampsia 1 | 67
sarcoidosis 1 | 368
tarsal-carpal coalition syndrome 1 | 3

Tissue

Cardiovascular System 7 | 17,958
Digestive Tract 7 | 18,473
Endocrine System 7 | 18,512
Female tissues 7 | 18,647
Liver and Pancreas 7 | 18,136
Male tissues 7 | 17,969
Nervous System 7 | 18,561
Respiratory system 7 | 17,484
Skin and soft tissues 7 | 18,115
Urinary Tract 7 | 18,444
Blood and immune system 6 | 17,995

Target Family

Non-IDG 5 | 11,969
Transcription Factor 2 | 1,400

GO Process

atrial cardiac muscle tissue m... 7 | 7
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pituitary homeobox 2 PITX2 Tbio Transcription Factor -2.62459 433.8 185
Endoglin ENG Tbio Non-IDG -3.07363 1147.6 1239
Myosin-6 MYH6 Tbio Non-IDG -2.94075 872.3 36
Protein Wnt-2 WNT2 Tbio Non-IDG -2.25852 155.5 156
Prospero homeobox protein 1 PROX1 Tbio Transcription Factor -2.28715 198.5 416
Noggin NOG Tbio Non-IDG -2.92882 783.1 315
Bone morphogenetic protein 10 BMP10 Tbio Non-IDG -1.39340 22.7 229