Development Level

Tchem 3 | 1,598
Tclin 3 | 613
Tbio 1 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal limb morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased circulating bilirubi... 1 | 19
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
increased blood urea nitrogen ... 1 | 48
increased heart rate variabili... 1 | 7
polycystic kidney 1 | 15
premature death 1 | 5
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2

Disease

Carcinoma 6 | 11,493
Depressive disorder 5 | 409
osteosarcoma 5 | 7,950
Cancer 4 | 2,499
Neurodegenerative disease 4 | 414
atypical teratoid / rhabdoid tumor 4 | 5,112
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
Alzheimer Disease 3 | 83
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Breast cancer 3 | 3,578
Cerebrovascular disease 3 | 238
Cognition Disorders 3 | 32
Deglutition Disorders 3 | 132
Dementia 3 | 175
Disease Models, Animal 3 | 155
Down syndrome 3 | 499
Forgetful 3 | 40
Learning Disorders 3 | 29
Memory Disorders 3 | 40
Memory Loss 3 | 40
Memory impairment 3 | 40
Mental Depression 3 | 333
Nerve Degeneration 3 | 121
Neurodegenerative Diseases 3 | 38
Neurodegenerative Disorders 3 | 79
Neurofibrillary degeneration (morphologic abnormality) 3 | 9
Parkinson's disease 3 | 392
Parkinsonian Disorders 3 | 56
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Seizures 3 | 596
Splenomegaly 3 | 190
Toxic encephalopathy 3 | 141
cutaneous lupus erythematosus 3 | 1,057
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
oligodendroglioma 3 | 2,850
subependymal giant cell astrocytoma 3 | 2,287
Abnormal brain FDG positron emission tomography 2 | 9
Adult onset 2 | 82
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Amyloidosis 2 | 67
Anxiety 2 | 136
Anxiety Disorders 2 | 38
Anxiety disease 2 | 113
Apathy 2 | 16
Aphasia 2 | 26
Apraxia 2 | 26
Apraxias 2 | 27
Behavioral variant of frontotemporal dementia 2 | 8
Bipolar Disorder 2 | 666
Brain disease 2 | 96
Cardiomyopathy, Dilated 2 | 83
Cerebral Hemorrhage 2 | 42
Chronic obstructive pulmonary disease 2 | 184
Compulsive hoarding 2 | 7
Cortical white matter abnormalities seen on MRI 2 | 18
Developmental arithmetic disorder 2 | 8
Dysarthria 2 | 192
Dysgraphia 2 | 20
Dyslexia 2 | 43
Dysphasia 2 | 23
Echolalia 2 | 12
Epilepsy 2 | 792
Excess nuchal skin 2 | 30
Frontotemporal cerebral atrophy 2 | 8
Frontotemporal dementia 2 | 51
Gliosis 2 | 56
Hyperorality 2 | 7
Hyperphagia 2 | 23
Increased appetite (finding) 2 | 23
Irritation - emotion 2 | 68
Isolated cases 2 | 72
Language Disorders 2 | 13
Leukoaraiosis 2 | 18
Liver Cirrhosis, Experimental 2 | 769
Loss of speech 2 | 16
Myoclonus 2 | 74
Neuronal loss 2 | 25
Personality change 2 | 23
Physical aggression 2 | 76
Pick's disease 2 | 15
Poor speech 2 | 37
Primitive reflexes (palmomental, snout, glabellar) 2 | 7
Problems speaking 2 | 37
Restlessness 2 | 14
Restrictive behavior 2 | 7
Restrictive behavior, interests, and activities 2 | 7
Skin cancer 2 | 469
Social disinhibition 2 | 14
Stereotyped Behavior 2 | 37
Stereotypic Movement Disorder 2 | 42
Tremor 2 | 113
Weight Loss 2 | 24
progressive supranuclear palsy 2 | 676

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Non-IDG 3 | 12,091
GPCR 2 | 408
Enzyme 1 | 4,145
Kinase 1 | 634

GO Process

astrocyte activation 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
Epidermal growth factor receptor EGFR Tclin Kinase -4.02650 10013.1 6418
Adenosine receptor A2a ADORA2A Tclin GPCR -2.98333 954.1 244
Amyloid-beta A4 protein APP Tchem Non-IDG -3.99225 9853.3 2781
Ciliary neurotrophic factor CNTF Tbio Non-IDG -2.96004 1015.5 485
Microtubule-associated protein tau MAPT Tchem Non-IDG -3.88207 7239.3 3951