Development Level

Tbio 41 | 11,445
Tchem 22 | 1,598
Tclin 7 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal bone structure 3 | 187
decreased body weight 3 | 161
increased startle reflex 3 | 112
preweaning lethality, incomple... 3 | 499
small superior vagus ganglion 3 | 74
abnormal embryo size 2 | 220
abnormal gait 2 | 69
decreased T cell number 2 | 15
decreased circulating creatini... 2 | 39
decreased heart weight 2 | 27
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
increased CD4-positive, alpha ... 2 | 4
limb grasping 2 | 41
abnormal cecum morphology 1 | 7
abnormal clavicle morphology 1 | 6
abnormal craniofacial morpholo... 1 | 33
abnormal digit morphology 1 | 10
abnormal eye size 1 | 7
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating glycerol... 1 | 16
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased spleen weight 1 | 10
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
tremors 1 | 39

Disease

Cancer 44 | 2,499
ovarian cancer 39 | 8,520
Carcinoma 38 | 11,493
lung cancer 34 | 4,740
psoriasis 34 | 6,694
glioblastoma 30 | 5,792
osteosarcoma 29 | 7,950
medulloblastoma, large-cell 27 | 6,241
lung carcinoma 24 | 2,843
malignant mesothelioma 22 | 3,232
atypical teratoid / rhabdoid tumor 20 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
cutaneous lupus erythematosus 19 | 1,057
interstitial cystitis 19 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
tuberculosis 18 | 2,010
Astrocytoma, Pilocytic 16 | 3,081
Rheumatoid arthritis 16 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
Breast cancer 15 | 3,578
group 3 medulloblastoma 15 | 4,104
non-small cell lung cancer 15 | 2,890
pancreatic cancer 15 | 2,398
Hypersensitivity reaction type II disease 14 | 253
adult high grade glioma 14 | 3,801
diabetes mellitus 14 | 1,728
subependymal giant cell astrocytoma 14 | 2,287
ulcerative colitis 14 | 1,819
ependymoma 13 | 4,679
invasive ductal carcinoma 13 | 2,951
primitive neuroectodermal tumor 13 | 3,035
group 4 medulloblastoma 12 | 1,855
Schizophrenia 11 | 1,160
adrenocortical carcinoma 11 | 1,428
cystic fibrosis 11 | 1,696
lung adenocarcinoma 11 | 2,716
pituitary cancer 11 | 1,972
Arthritis 10 | 290
juvenile dermatomyositis 9 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Arthritis, Rheumatoid 8 | 174
Autosomal recessive predisposition 8 | 1,442
Prostatic Neoplasms 8 | 495
Splenomegaly 8 | 190
Vascular disease 8 | 319
active Crohn's disease 8 | 922
breast carcinoma 8 | 1,638
pediatric high grade glioma 8 | 1,064
primary Sjogren syndrome 8 | 735
Asthma 7 | 385
Immunologic Deficiency Syndromes 7 | 113
Multiple myeloma 7 | 1,332
Pick disease 7 | 1,894
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
dermatomyositis 7 | 966
gastric carcinoma 7 | 807
Atherosclerosis 6 | 291
Bipolar Disorder 6 | 666
Diabetes Mellitus, Experimental 6 | 108
Duchenne muscular dystrophy 6 | 601
Hepatomegaly 6 | 285
Kidney cancer 6 | 2,613
Kidney disease 6 | 430
Liver disease 6 | 237
Lung Neoplasms 6 | 232
Melanoma 6 | 711
Multiple Sclerosis 6 | 540
Short stature 6 | 531
aldosterone-producing adenoma 6 | 665
oligodendroglioma 6 | 2,850
pancreatic carcinoma 6 | 562
periodontitis 6 | 293
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
Autoimmune lymphoproliferative syndrome 5 | 11
Brain Injuries 5 | 65
Breast Neoplasms 5 | 445
Chronic Lymphocytic Leukemia 5 | 262
Epilepsy 5 | 792
Gaucher disease type 3 5 | 67
Inflammatory bowel disease 5 | 151
Influenza 5 | 142
Liver Cirrhosis, Experimental 5 | 769
Lung disease 5 | 142
Lymphoproliferative syndrome 5 | 58
Mammary Neoplasms 5 | 425
Neoplasm Metastasis 5 | 168
Nerve Degeneration 5 | 121
Pneumonia 5 | 174
Skin Neoplasms 5 | 69
Vasculitis 5 | 80
active ulcerative colitis 5 | 764
colon cancer 5 | 1,478
non-small cell lung carcinoma 5 | 317
Depressive disorder 4 | 409
acute myeloid leukemia 4 | 783
esophageal adenocarcinoma 4 | 737
fibroadenoma 4 | 559
hepatocellular carcinoma 4 | 547

Tissue

Digestive Tract 69 | 17,369
Female tissues 69 | 17,400
Liver and Pancreas 69 | 16,750
Male tissues 69 | 17,142
Nervous System 69 | 16,725
Respiratory system 69 | 16,393
Skin and soft tissues 69 | 17,230
Urinary Tract 69 | 16,678
Blood and immune system 68 | 16,909
Endocrine System 68 | 18,159
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 48 | 12,091
Enzyme 9 | 4,145
Kinase 8 | 634
Epigenetic 2 | 242
Ion Channel 2 | 344
GPCR 1 | 408
Nuclear Receptor 1 | 48

GO Process

apoptotic signaling pathway 71 | 71
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
CASP8-associated protein 2 CASP8AP2 Tbio Non-IDG 0.00000 0
Interferon alpha-inducible protein 27, mitochondrial IFI27 Tbio Non-IDG -1.51419 33.3 0
Caspase-2 CASP2 Tchem Enzyme -2.62373 431.8 571
Tumor necrosis factor receptor superfamily member 25 TNFRSF25 Tbio Non-IDG -3.25237 1888.2 535
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493
Tumor necrosis factor ligand superfamily member 12 TNFSF12 Tbio Non-IDG -2.49751 362.7 413
Lymphocyte antigen 96 LY96 Tchem Non-IDG -2.77678 541.2 369
Tumor necrosis factor receptor superfamily member 5 CD40 Tchem Non-IDG -3.50040 3120.3 1879