Development Level

Tbio 45 | 11,651
Tchem 18 | 1,388
Tclin 7 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal bone structure 3 | 187
decreased body weight 3 | 161
increased startle reflex 3 | 112
preweaning lethality, incomple... 3 | 499
small superior vagus ganglion 3 | 74
abnormal embryo size 2 | 220
abnormal gait 2 | 69
decreased T cell number 2 | 15
decreased circulating creatini... 2 | 39
decreased heart weight 2 | 27
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
increased CD4-positive, alpha ... 2 | 4
limb grasping 2 | 41
abnormal cecum morphology 1 | 7
abnormal clavicle morphology 1 | 6
abnormal craniofacial morpholo... 1 | 33
abnormal digit morphology 1 | 10
abnormal eye size 1 | 7
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating glycerol... 1 | 16
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased spleen weight 1 | 10
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
tremors 1 | 39

Disease

Cancer 44 | 2,499
ovarian cancer 39 | 8,520
Carcinoma 38 | 11,493
lung cancer 34 | 4,740
psoriasis 34 | 6,694
glioblastoma 30 | 5,792
osteosarcoma 29 | 7,950
medulloblastoma, large-cell 27 | 6,241
lung carcinoma 24 | 2,843
malignant mesothelioma 22 | 3,232
atypical teratoid / rhabdoid tumor 20 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
cutaneous lupus erythematosus 19 | 1,057
interstitial cystitis 19 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
tuberculosis 18 | 2,010
Astrocytoma, Pilocytic 16 | 3,081
Rheumatoid arthritis 16 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
Breast cancer 15 | 3,578
group 3 medulloblastoma 15 | 4,104
non-small cell lung cancer 15 | 2,890
pancreatic cancer 15 | 2,398
Hypersensitivity reaction type II disease 14 | 253
adult high grade glioma 14 | 3,801
diabetes mellitus 14 | 1,728
subependymal giant cell astrocytoma 14 | 2,287
ulcerative colitis 14 | 1,819
ependymoma 13 | 4,679
invasive ductal carcinoma 13 | 2,951
primitive neuroectodermal tumor 13 | 3,035
group 4 medulloblastoma 12 | 1,855
Schizophrenia 11 | 1,160
adrenocortical carcinoma 11 | 1,428
cystic fibrosis 11 | 1,696
lung adenocarcinoma 11 | 2,716
pituitary cancer 11 | 1,972
Arthritis 10 | 290
juvenile dermatomyositis 9 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Arthritis, Rheumatoid 8 | 174
Autosomal recessive predisposition 8 | 1,442
Prostatic Neoplasms 8 | 495
Splenomegaly 8 | 190
Vascular disease 8 | 319
active Crohn's disease 8 | 922
breast carcinoma 8 | 1,638
pediatric high grade glioma 8 | 1,064
primary Sjogren syndrome 8 | 735
Asthma 7 | 385
Immunologic Deficiency Syndromes 7 | 113
Multiple myeloma 7 | 1,332
Pick disease 7 | 1,894
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
dermatomyositis 7 | 966
gastric carcinoma 7 | 807
Atherosclerosis 6 | 291
Bipolar Disorder 6 | 666
Diabetes Mellitus, Experimental 6 | 108
Duchenne muscular dystrophy 6 | 601
Hepatomegaly 6 | 285
Kidney cancer 6 | 2,613
Kidney disease 6 | 430
Liver disease 6 | 237
Lung Neoplasms 6 | 232
Melanoma 6 | 711
Multiple Sclerosis 6 | 540
Short stature 6 | 531
aldosterone-producing adenoma 6 | 665
oligodendroglioma 6 | 2,850
pancreatic carcinoma 6 | 562
periodontitis 6 | 293
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
Autoimmune lymphoproliferative syndrome 5 | 11
Brain Injuries 5 | 65
Breast Neoplasms 5 | 445
Chronic Lymphocytic Leukemia 5 | 262
Epilepsy 5 | 792
Gaucher disease type 3 5 | 67
Inflammatory bowel disease 5 | 151
Influenza 5 | 142
Liver Cirrhosis, Experimental 5 | 769
Lung disease 5 | 142
Lymphoproliferative syndrome 5 | 58
Mammary Neoplasms 5 | 425
Neoplasm Metastasis 5 | 168
Nerve Degeneration 5 | 121
Pneumonia 5 | 174
Skin Neoplasms 5 | 69
Vasculitis 5 | 80
active ulcerative colitis 5 | 764
colon cancer 5 | 1,478
non-small cell lung carcinoma 5 | 317
Depressive disorder 4 | 409
acute myeloid leukemia 4 | 783
esophageal adenocarcinoma 4 | 737
fibroadenoma 4 | 559
hepatocellular carcinoma 4 | 547

Tissue

Digestive Tract 69 | 17,369
Female tissues 69 | 17,400
Liver and Pancreas 69 | 16,750
Male tissues 69 | 17,142
Nervous System 69 | 16,725
Respiratory system 69 | 16,393
Skin and soft tissues 69 | 17,230
Urinary Tract 69 | 16,678
Blood and immune system 68 | 16,909
Endocrine System 68 | 18,159
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 48 | 12,091
Enzyme 9 | 4,145
Kinase 8 | 634
Epigenetic 2 | 242
Ion Channel 2 | 344
GPCR 1 | 408
Nuclear Receptor 1 | 48

GO Process

apoptotic signaling pathway 71 | 71
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 4 TNFRSF4 Tbio Non-IDG -2.60147 430.2 524
Tumor necrosis factor receptor superfamily member 18 TNFRSF18 Tbio Non-IDG -2.34111 233.7 604
Death-inducer obliterator 1 DIDO1 Tbio Epigenetic -1.14284 15.7 184
TM2 domain-containing protein 1 TM2D1 Tdark Non-IDG -0.35218 1.53 40
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060
Tumor necrosis factor receptor superfamily member 9 TNFRSF9 Tbio Non-IDG -2.83886 770.0 684
Death-associated protein 1 DAP Tbio Non-IDG -2.28005 160.9 183
28S ribosomal protein S29, mitochondrial DAP3 Tbio Non-IDG -1.22289 22.6 312
Tumor necrosis factor receptor superfamily member 8 TNFRSF8 Tclin Non-IDG -3.45141 2817.5 1193
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559