Development Level

Tbio 363 | 11,445
Tchem 101 | 1,598
Tdark 27 | 6,588
Tclin 20 | 613

Collection

Kinase: IDG Consortium (Target... 8 | 125
Kinase: IDG Consortium (Comple... 5 | 37
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 30 | 979
abnormal behavior 15 | 298
hypoactivity 12 | 132
abnormal bone structure 11 | 187
preweaning lethality, incomple... 11 | 499
decreased vertical activity 9 | 208
decreased bone mineral content 8 | 151
embryonic lethality prior to t... 8 | 278
hyperactivity 8 | 148
increased lean body mass 8 | 172
decreased mean corpuscular vol... 7 | 79
embryonic lethality prior to o... 7 | 239
enlarged heart 7 | 210
increased circulating alkaline... 7 | 122
abnormal embryo size 6 | 220
abnormal gait 6 | 69
increased startle reflex 6 | 112
abnormal seminal vesicle morph... 5 | 114
decreased bone mineral density 5 | 126
increased bone mineral density 5 | 72
increased leukocyte cell numbe... 5 | 47
abnormal bone mineralization 4 | 38
abnormal coat-hair pigmentatio... 4 | 64
abnormal heart morphology 4 | 162
decreased body weight 4 | 161
decreased lean body mass 4 | 135
decreased mean corpuscular hem... 4 | 50
decreased total body fat amoun... 4 | 207
impaired glucose tolerance 4 | 75
increased neutrophil cell numb... 4 | 46
increased total body fat amoun... 4 | 134
male infertility 4 | 123
small superior vagus ganglion 4 | 74
thrombocytopenia 4 | 56
abnormal behavioral response t... 3 | 66
abnormal retina morphology 3 | 71
decreased circulating glucose ... 3 | 126
decreased circulating iron lev... 3 | 32
decreased neutrophil cell numb... 3 | 42
decreased prepulse inhibition 3 | 82
embryonic growth retardation 3 | 106
enlarged lymph nodes 3 | 37
increased bone mineral content 3 | 108
increased circulating HDL chol... 3 | 80
increased circulating amylase ... 3 | 25
increased circulating choleste... 3 | 66
increased circulating glucose ... 3 | 24
increased circulating sodium l... 3 | 71
increased heart weight 3 | 62
increased lymphocyte cell numb... 3 | 32
increased mean corpuscular hem... 3 | 96
increased or absent threshold ... 3 | 101
prenatal lethality prior to he... 3 | 87
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal limb morphology 2 | 13
abnormal lung morphology 2 | 26
abnormal spleen morphology 2 | 55
abnormal tail movements 2 | 12
abnormal vibrissa morphology 2 | 25
cyanosis 2 | 7
decreased circulating HDL chol... 2 | 68
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating insulin ... 2 | 76
decreased circulating potassiu... 2 | 20
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased granulocyte number 2 | 6
decreased grip strength 2 | 116
decreased heart left ventricle... 2 | 28
decreased heart weight 2 | 27
decreased hematocrit 2 | 46
decreased lymphocyte cell numb... 2 | 83
decreased total retina thickne... 2 | 17
dilated heart left ventricle 2 | 11
enlarged spleen 2 | 41
female infertility 2 | 60
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased circulating calcium ... 2 | 34
increased circulating free fat... 2 | 20
increased circulating potassiu... 2 | 29
increased circulating triglyce... 2 | 42
increased grip strength 2 | 41
increased heart rate 2 | 23
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
increased red blood cell distr... 2 | 34
limb grasping 2 | 41
short tibia 2 | 97
tremors 2 | 39
decreased circulating bilirubi... 1 | 19
decreased mean corpuscular hem... 1 | 31
increased circulating phosphat... 1 | 26

Disease

Carcinoma 311 | 11,493
ovarian cancer 295 | 8,520
osteosarcoma 233 | 7,950
psoriasis 214 | 6,694
glioblastoma 210 | 5,792
lung cancer 207 | 4,740
medulloblastoma, large-cell 206 | 6,241
Cancer 188 | 2,499
atypical teratoid / rhabdoid tumor 147 | 5,112
ependymoma 136 | 4,679
adult high grade glioma 129 | 3,801
Breast cancer 128 | 3,578
malignant mesothelioma 126 | 3,232
non-small cell lung cancer 125 | 2,890
group 3 medulloblastoma 122 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 119 | 3,291
lung carcinoma 114 | 2,843
invasive ductal carcinoma 112 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 110 | 2,989
Astrocytoma, Pilocytic 106 | 3,081
lung adenocarcinoma 105 | 2,716
pancreatic cancer 95 | 2,398
oligodendroglioma 94 | 2,850
tuberculosis 93 | 2,010
interstitial cystitis 92 | 2,312
subependymal giant cell astrocytoma 91 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 87 | 2,955
primitive neuroectodermal tumor 87 | 3,035
pituitary cancer 77 | 1,972
astrocytic glioma 76 | 2,597
ulcerative colitis 75 | 1,819
Kidney cancer 72 | 2,613
breast carcinoma 70 | 1,638
diabetes mellitus 69 | 1,728
ductal carcinoma in situ 67 | 1,745
colon cancer 66 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 64 | 1,962
cystic fibrosis 62 | 1,696
Pick disease 61 | 1,894
group 4 medulloblastoma 61 | 1,855
Multiple myeloma 60 | 1,332
cutaneous lupus erythematosus 60 | 1,057
Rheumatoid arthritis 57 | 1,191
adrenocortical carcinoma 54 | 1,428
Schizophrenia 53 | 1,160
juvenile dermatomyositis 49 | 1,187
nasopharyngeal carcinoma 49 | 1,058
dermatomyositis 44 | 966
primary pancreatic ductal adenocarcinoma 44 | 1,109
acute quadriplegic myopathy 42 | 1,158
spina bifida 41 | 1,074
esophageal adenocarcinoma 40 | 737
Alzheimer's disease 39 | 658
gastric carcinoma 38 | 807
primary Sjogren syndrome 38 | 735
Multiple Sclerosis 37 | 540
Prostatic Neoplasms 37 | 495
Autosomal recessive predisposition 36 | 1,442
Breast Neoplasms 36 | 445
Liver Cirrhosis, Experimental 36 | 769
Mammary Neoplasms 36 | 425
Waldenstrons macroglobulinemia 36 | 765
Atopic dermatitis 35 | 952
Melanoma 35 | 711
active ulcerative colitis 35 | 764
astrocytoma 35 | 1,146
pediatric high grade glioma 35 | 1,064
Intellectual disability 34 | 1,016
aldosterone-producing adenoma 33 | 665
active Crohn's disease 30 | 922
Stomach Neoplasms 29 | 300
Vascular disease 29 | 319
acute myeloid leukemia 29 | 783
Asthma 28 | 385
Bipolar Disorder 26 | 666
Liver cancer 26 | 604
Lung Neoplasms 26 | 232
hepatocellular carcinoma 26 | 547
Hypersensitivity reaction type II disease 25 | 253
Kidney disease 25 | 430
Obesity 25 | 678
Short stature 25 | 531
non primary Sjogren syndrome sicca 25 | 891
Arthritis 24 | 290
Colorectal Neoplasms 24 | 243
Neurodegenerative disease 24 | 414
Duchenne muscular dystrophy 22 | 601
Renal Cell Carcinoma 22 | 214
Crohn's disease 21 | 321
Dull intelligence 21 | 645
Low intelligence 21 | 645
Mental Retardation 21 | 645
Mental deficiency 21 | 645
Poor school performance 21 | 645
pancreatic carcinoma 21 | 562
progressive supranuclear palsy 21 | 676
Colonic Neoplasms 20 | 142
Down syndrome 20 | 499
Endometriosis 20 | 540
gastric cancer 20 | 459

Tissue

Endocrine System 497 | 18,159
Digestive Tract 495 | 17,369
Female tissues 494 | 17,400
Skin and soft tissues 491 | 17,230
Blood and immune system 489 | 16,909
Male tissues 489 | 17,142
Liver and Pancreas 486 | 16,750
Nervous System 486 | 16,725
Respiratory system 486 | 16,393
Urinary Tract 485 | 16,678
Cardiovascular System 457 | 15,192

Target Family

Non-IDG 312 | 12,091
Enzyme 97 | 4,145
Kinase 57 | 634
Transcription Factor 22 | 1,400
Epigenetic 8 | 242
GPCR 7 | 408
Transporter 3 | 473
Ion Channel 2 | 344
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

GO Process

apoptotic process 511 | 511
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras association domain-containing protein 5 RASSF5 Tbio Non-IDG -1.81149 71.3 155
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
E3 ubiquitin-protein ligase TRAF7 TRAF7 Tbio Enzyme -1.09531 13.0 112
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182
Serine/threonine-protein kinase TAO2 TAOK2 Tchem Kinase -1.52454 36.1 154
Ubiquitin carboxyl-terminal hydrolase 17-like protein 3 USP17L3 Tdark Enzyme -0.71476 13.1 15
Transmembrane protein 14A TMEM14A Tbio Non-IDG -0.33645 3.05 17
Rhotekin RTKN Tbio Non-IDG -1.49615 24.3 137
Protein fem-1 homolog B FEM1B Tbio Non-IDG -1.23011 18.1 144