Development Level

Tbio 12 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal QT variability 1 | 10
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
absent spleen 1 | 3
decreased bone mineral density 1 | 126
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
small testis 1 | 58

Disease

ovarian cancer 9 | 8,520
Cancer 8 | 2,499
lung cancer 8 | 4,740
osteosarcoma 8 | 7,950
psoriasis 7 | 6,694
Carcinoma 5 | 11,493
Pick disease 5 | 1,894
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
dermatomyositis 4 | 966
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
ulcerative colitis 4 | 1,819
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Arthritis 3 | 290
Schizophrenia 3 | 1,160
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
Brain disease 2 | 96
Cerebrovascular disease 2 | 238
Endometriosis 2 | 540
Hypersensitivity reaction type II disease 2 | 253
Infertility 2 | 188
Liver cancer 2 | 604
Lung disease 2 | 142
Lupus erythematosus 2 | 57
Multiple myeloma 2 | 1,332
Myocardial Infarction 2 | 151
Myocardial Reperfusion Injury 2 | 37
Obesity 2 | 678
Pancreatitis 2 | 123
Rheumatoid arthritis 2 | 1,191
Sepsis 2 | 24
Sertoli-Leydig cell tumor 2 | 5
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
diabetes mellitus 2 | 1,728
head and neck cancer 2 | 271
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
medulloblastoma 2 | 720
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
Amenorrhea 1 | 58
Angioedema 1 | 38
Basal cell nevi 1 | 23
Calcific tendinitis 1 | 8
Calcinosis 1 | 70
Cholestasis, Extrahepatic 1 | 25
Chromosome 22q11.2 microduplication syndrome 1 | 8
Coloboma 1 | 51
Conjunctivitis 1 | 53
DiGeorge syndrome 1 | 47
Elevated gonadotropins 1 | 15
Epicanthus inversus 1 | 3
Exanthema 1 | 43
Granulosa cell tumor 1 | 6
Heart valve disease 1 | 39
Hereditary spherocytosis 1 | 16
Hyperglycemia 1 | 137
Imperforate anus 1 | 25
Irregular hyperpigmentation 1 | 33
Keloid 1 | 37
Laryngostenosis 1 | 10
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Microphthalmia 1 | 76
Oligospermia 1 | 36
Ovarian dysfunction 1 | 18
Papillary thyroid carcinoma 1 | 43
Pericarditis 1 | 13
Premature Menopause 1 | 31
Premature ovarian failure 1 | 65
Pulmonary Fibrosis 1 | 106
Renal glomerular disease 1 | 12
Rhabdomyosarcoma 1 | 39
Seminoma 1 | 15
Skin tag 1 | 14
Uveitis 1 | 103
Velocardiofacial syndrome 1 | 46
Wilms Tumor 1 | 28
blepharophimosis, ptosis, and epicanthus inversus syndrome 1 | 8

Tissue

Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Skin and soft tissues 15 | 17,230
Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Liver and Pancreas 14 | 16,750
Respiratory system 14 | 16,393
Cardiovascular System 13 | 15,192
Urinary Tract 13 | 16,678

Target Family

Enzyme 6 | 4,145
Non-IDG 5 | 12,091
Transcription Factor 3 | 1,400
Epigenetic 1 | 242

GO Process

apoptotic DNA fragmentation 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Endoribonuclease Dicer DICER1 Tbio Enzyme -3.34177 2054.3 327
Histone H1.0 H1F0 Tchem Non-IDG -3.33534 2040.0 328
High mobility group protein B1 HMGB1 Tbio Transcription Factor -3.05199 2190.4 1145
Forkhead box protein L2 FOXL2 Tbio Transcription Factor -2.81557 652.1 234
DNA fragmentation factor subunit alpha DFFA Tbio Non-IDG -2.50636 314.8 667
Deoxyribonuclease gamma DNASE1L3 Tbio Enzyme -2.31583 207.3 157
Endonuclease G, mitochondrial ENDOG Tbio Enzyme -2.22791 175.9 334
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.17030 147.0 44
Deoxyribonuclease-2-alpha DNASE2 Tbio Enzyme -2.03290 109.6 134