Development Level

Tbio 86 | 11,445
Tchem 14 | 1,598
Tdark 10 | 6,588

IMPC Phenotype

preweaning lethality, complete... 15 | 979
decreased total body fat amoun... 4 | 207
preweaning lethality, incomple... 4 | 499
decreased circulating choleste... 3 | 93
impaired glucose tolerance 3 | 75
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal seminal vesicle morph... 2 | 114
absent pinna reflex 2 | 23
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating free fat... 2 | 31
decreased mean corpuscular vol... 2 | 79
increased circulating free fat... 2 | 20
prenatal lethality prior to he... 2 | 87
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
short tibia 2 | 97
abnormal cecum morphology 1 | 7
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal skin coloration 1 | 25
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal stomach morphology 1 | 10
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
microphthalmia 1 | 26
premature death 1 | 5
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 63 | 8,520
Carcinoma 57 | 11,493
glioblastoma 47 | 5,792
psoriasis 40 | 6,694
osteosarcoma 38 | 7,950
lung cancer 37 | 4,740
adult high grade glioma 34 | 3,801
atypical teratoid / rhabdoid tumor 34 | 5,112
medulloblastoma, large-cell 32 | 6,241
Rheumatoid arthritis 31 | 1,191
lung carcinoma 29 | 2,843
invasive ductal carcinoma 27 | 2,951
Breast cancer 26 | 3,578
ependymoma 26 | 4,679
non-small cell lung cancer 26 | 2,890
diabetes mellitus 24 | 1,728
malignant mesothelioma 24 | 3,232
Astrocytoma, Pilocytic 22 | 3,081
adrenocortical carcinoma 22 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
subependymal giant cell astrocytoma 22 | 2,287
breast carcinoma 21 | 1,638
group 3 medulloblastoma 20 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
interstitial cystitis 18 | 2,312
Narcolepsy 17 | 72
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
pancreatic cancer 16 | 2,398
primitive neuroectodermal tumor 16 | 3,035
tuberculosis 16 | 2,010
Berylliosis 15 | 28
Systemic lupus erythematosus 15 | 194
astrocytoma 15 | 1,146
lung adenocarcinoma 15 | 2,716
oligodendroglioma 15 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
sarcoidosis 15 | 370
Cancer 14 | 2,499
Multiple Sclerosis, Susceptibility to 14 | 15
Narcolepsy-cataplexy 14 | 21
active Crohn's disease 14 | 922
colon cancer 14 | 1,478
juvenile dermatomyositis 14 | 1,187
Atopic dermatitis 13 | 952
Diffuse cutaneous systemic sclerosis 13 | 17
Rheumatoid Arthritis, Systemic Juvenile 13 | 16
Sarcoidosis 1 13 | 14
follicular lymphoma 13 | 20
limited scleroderma 13 | 19
primary Sjogren syndrome 13 | 735
Duchenne muscular dystrophy 12 | 601
Multiple Sclerosis 12 | 540
cutaneous lupus erythematosus 12 | 1,057
ductal carcinoma in situ 12 | 1,745
esophageal adenocarcinoma 12 | 737
pituitary cancer 12 | 1,972
Kidney cancer 11 | 2,613
Multiple myeloma 11 | 1,332
acute quadriplegic myopathy 11 | 1,158
Pick disease 10 | 1,894
active ulcerative colitis 10 | 764
astrocytic glioma 10 | 2,597
ulcerative colitis 10 | 1,819
Autosomal recessive predisposition 9 | 1,442
Endometriosis 9 | 540
Neurodegenerative disease 9 | 414
Waldenstrons macroglobulinemia 9 | 765
cystic fibrosis 8 | 1,696
dermatomyositis 8 | 966
Hypersensitivity reaction type II disease 7 | 253
Juvenile rheumatoid arthritis 7 | 111
Muscle hypotonia 7 | 571
Neuropathy 7 | 261
Type 1 diabetes mellitus 7 | 109
acute myeloid leukemia 7 | 783
group 4 medulloblastoma 7 | 1,855
head and neck cancer and chronic obstructive pulmonary disease 7 | 239
spina bifida 7 | 1,074
Arthritis, Rheumatoid 6 | 174
Becker muscular dystrophy 6 | 191
Bipolar Disorder 6 | 666
Cognitive delay 6 | 608
Down syndrome 6 | 499
Epilepsy 6 | 792
Global developmental delay 6 | 608
Intellectual disability 6 | 1,016
Liver Cirrhosis, Experimental 6 | 769
Mental and motor retardation 6 | 608
Schizophrenia 6 | 1,160
hereditary spastic paraplegia 6 | 318
mucosa-associated lymphoid tissue lymphoma 6 | 484
nasopharyngeal carcinoma 6 | 1,058
non primary Sjogren syndrome sicca 6 | 891
Asthma 5 | 385
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Short stature 5 | 531
Small head 5 | 374

Tissue

Endocrine System 94 | 18,159
Liver and Pancreas 93 | 16,750
Skin and soft tissues 93 | 17,230
Blood and immune system 92 | 16,909
Digestive Tract 92 | 17,369
Female tissues 92 | 17,400
Male tissues 92 | 17,142
Respiratory system 92 | 16,393
Urinary Tract 92 | 16,678
Cardiovascular System 88 | 15,192
Nervous System 87 | 16,725

Target Family

Non-IDG 98 | 12,091
Enzyme 12 | 4,145

GO Process

antigen processing and present... 110 | 110
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF26A KIF26A Tdark Non-IDG -0.20165 1.48 70
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Kinesin heavy chain isoform 5A KIF5A Tbio Non-IDG -1.69131 48.4 170
Kinesin-like protein KIF2C KIF2C Tbio Non-IDG -2.12404 136.3 256
Kinesin-like protein KIF11 KIF11 Tchem Non-IDG -2.61375 404.4 300
Cytoplasmic dynein 1 light intermediate chain 2 DYNC1LI2 Tbio Non-IDG -0.61455 3.87 95
Oxysterol-binding protein-related protein 1 OSBPL1A Tbio Non-IDG -0.69214 5.13 145
Actin-related protein 10 ACTR10 Tbio Non-IDG -0.75524 5.22 61
HLA class II histocompatibility antigen, DRB1-14 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 489