Development Level

Tbio 5 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal lens morphology 1 | 81
decreased blood urea nitrogen ... 1 | 51
decreased circulating LDL chol... 1 | 38
decreased circulating magnesiu... 1 | 13
embryonic lethality prior to t... 1 | 278
increased circulating LDL chol... 1 | 13
increased mean corpuscular hem... 1 | 96
preweaning lethality, complete... 1 | 979

Disease

Cancer 9 | 2,499
Carcinoma 7 | 11,493
Kidney cancer 7 | 2,613
ovarian cancer 7 | 8,520
Breast cancer 5 | 3,578
Epilepsy 5 | 792
Intellectual disability 5 | 1,016
lung cancer 5 | 4,740
Acquired scoliosis 4 | 281
Attention deficit hyperactivity disorder 4 | 278
Carcinoma, Squamous Cell 4 | 110
Curvature of spine 4 | 282
Dull intelligence 4 | 645
Low intelligence 4 | 645
Lung Neoplasms 4 | 232
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Renal Cell Carcinoma 4 | 214
Seizures 4 | 596
Squamous cell carcinoma 4 | 129
atypical teratoid / rhabdoid tumor 4 | 5,112
breast carcinoma 4 | 1,638
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Abdominal Pain 3 | 98
Abnormality of metabolism/homeostasis 3 | 134
Adenocarcinoma 3 | 122
Alzheimer's disease 3 | 658
Breast Neoplasms 3 | 445
Byzanthine arch palate 3 | 194
Carcinoma, Hepatocellular 3 | 228
Cataract 3 | 297
Cognitive delay 3 | 608
Cowden disease 3 | 18
Downward slant of palpebral fissure 3 | 158
Endometrial cancer 3 | 311
Fibrous skin tumor of tuberous sclerosis 3 | 18
Gastrointestinal hamartomatous polyps 3 | 10
Global developmental delay 3 | 608
Gynecomastia 3 | 64
Hamartomatous polyp 3 | 10
Hypoplastic mandible condyle 3 | 275
Hypothyroidism 3 | 122
Isolated cases 3 | 72
Lens Opacities 3 | 231
Liver carcinoma 3 | 240
Mammary Neoplasms 3 | 425
Mandibular hypoplasia 3 | 275
Mental and motor retardation 3 | 608
Micrognathism 3 | 275
Multiple, subcutaneous nodules 3 | 53
Obesity 3 | 678
Orbital separation excessive 3 | 244
Ovarian Cysts 3 | 41
Ovarian Neoplasms 3 | 102
Papule 3 | 43
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
Sebaceous adenoma 3 | 26
Skin tag 3 | 14
Somatic mutation 3 | 61
Subcutaneous nodule 3 | 53
diabetes mellitus 3 | 1,728
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
Asymmetric growth 2 | 5
Carcinoma of colon 2 | 32
Carcinoma, Renal Cell 2 | 124
Decreased projection of maxilla 2 | 66
Deficiency of upper jaw bones 2 | 66
Dental abnormalities 2 | 60
Dysgerminoma 2 | 11
Hemangioma, Cavernous 2 | 20
Hyperkeratosis 2 | 50
Hyperpigmented macules 2 | 42
Hypertrophy, Left Ventricular 2 | 24
Hypoplasia of the maxilla 2 | 66
Hypotrophic maxilla 2 | 66
Irregular hyperpigmentation 2 | 33
Kyphoscoliosis deformity of spine 2 | 60
Left Ventricular Hypertrophy 2 | 47
Lymphatic obstruction 2 | 21
Maxillary retrognathia 2 | 66
Meningioma 2 | 41
Onset of lymphedema around puberty 2 | 21
Palmoplantar keratosis 2 | 74
Retrusion of upper jaw bones 2 | 66
Skin disease 2 | 66
Squamous cell carcinoma of the head and neck 2 | 29
Syndactyly of fingers 2 | 48
Telangiectasia of the skin 2 | 39
Tooth Abnormalities 2 | 69
Varicocele 2 | 26
Visceral angiomatosis 2 | 13
Warts 2 | 10
hypopigmented skin patch 2 | 59
ovarian neoplasm 2 | 99

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Kinase 7 | 634
Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400

GO Process

anoikis 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Death-associated protein kinase 2 DAPK2 Tchem Kinase -1.39206 28.7 440
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Tuberin TSC2 Tbio Non-IDG -2.99381 1000.6 1632
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.36734 20160.1 3565
Serine/threonine-protein kinase STK11 STK11 Tchem Kinase -2.96288 998.3 959
Serine/threonine-protein kinase mTOR MTOR Tclin Kinase -3.89596 7790.5 1195
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform PIK3CA Tclin Kinase -3.04988 1076.8 484
Transcription factor Dp-1 TFDP1 Tbio Transcription Factor -1.60201 42.3 256
Bcl-2-modifying factor BMF Tbio Non-IDG -1.72791 52.2 327