Development Level

Tbio 24 | 11,445
Tchem 17 | 1,598
Tclin 5 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal sleep behavior 2 | 70
embryonic lethality prior to o... 2 | 239
enlarged uterus 2 | 11
hydrometra 2 | 53
impaired glucose tolerance 2 | 75
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
abnormal behavior 1 | 298
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 76
decreased lean body mass 1 | 135
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
increased circulating alkaline... 1 | 122
increased fasted circulating g... 1 | 76
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
male infertility 1 | 123
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Cancer 32 | 2,499
Carcinoma 32 | 11,493
ovarian cancer 29 | 8,520
lung cancer 28 | 4,740
glioblastoma 26 | 5,792
medulloblastoma, large-cell 23 | 6,241
psoriasis 22 | 6,694
non-small cell lung cancer 20 | 2,890
osteosarcoma 20 | 7,950
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
malignant mesothelioma 17 | 3,232
ependymoma 16 | 4,679
Liver Cirrhosis, Experimental 15 | 769
adrenocortical carcinoma 15 | 1,428
interstitial cystitis 15 | 2,312
invasive ductal carcinoma 15 | 2,951
lung adenocarcinoma 15 | 2,716
atypical teratoid / rhabdoid tumor 14 | 5,112
diabetes mellitus 14 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
lung carcinoma 14 | 2,843
Breast cancer 13 | 3,578
pancreatic cancer 13 | 2,398
tuberculosis 13 | 2,010
ulcerative colitis 13 | 1,819
Astrocytoma, Pilocytic 11 | 3,081
Autosomal recessive predisposition 11 | 1,442
Kidney cancer 11 | 2,613
ductal carcinoma in situ 11 | 1,745
group 3 medulloblastoma 11 | 4,104
oligodendroglioma 11 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
primitive neuroectodermal tumor 11 | 3,035
Carcinoma, Hepatocellular 10 | 228
Liver carcinoma 10 | 240
adult high grade glioma 10 | 3,801
breast carcinoma 10 | 1,638
group 4 medulloblastoma 10 | 1,855
mucosa-associated lymphoid tissue lymphoma 10 | 484
Coronary artery disease 9 | 268
Liver disease 9 | 237
Rheumatoid arthritis 9 | 1,191
astrocytoma 9 | 1,146
colon cancer 9 | 1,478
cystic fibrosis 9 | 1,696
pediatric high grade glioma 9 | 1,064
Atopic dermatitis 8 | 952
Hypertension 8 | 396
Obesity 8 | 678
Schizophrenia 8 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
Atherosclerosis 7 | 291
Cerebrovascular disease 7 | 238
Multiple myeloma 7 | 1,332
acute quadriplegic myopathy 7 | 1,158
cutaneous lupus erythematosus 7 | 1,057
juvenile dermatomyositis 7 | 1,187
pituitary cancer 7 | 1,972
Alzheimer's disease 6 | 658
Colonic Neoplasms 6 | 142
Duchenne muscular dystrophy 6 | 601
Heart disease 6 | 306
Kidney disease 6 | 430
Pick disease 6 | 1,894
Vascular disease 6 | 319
dermatomyositis 6 | 966
nasopharyngeal carcinoma 6 | 1,058
Acute kidney injury 5 | 70
Adenoma 5 | 167
Arthritis 5 | 290
Diabetic Nephropathies 5 | 37
Endometriosis 5 | 540
Fatty liver disease 5 | 103
Hypertensive disease 5 | 292
Lipid metabolism disorder 5 | 114
Multiple Sclerosis 5 | 540
Neoplasm Invasiveness 5 | 161
Neuropathy 5 | 261
Osteoporosis 5 | 363
Peripheral Neuropathy 5 | 134
Prostatic Neoplasms 5 | 495
Stomach Neoplasms 5 | 300
active ulcerative colitis 5 | 764
astrocytic glioma 5 | 2,597
gastric cancer 5 | 459
limb girdle muscular dystrophy 2A 5 | 213
Arthritis, Rheumatoid 4 | 174
Becker muscular dystrophy 4 | 191
Epilepsy 4 | 792
Myocardial Ischemia 4 | 169
Seizures 4 | 596
Type 2 diabetes mellitus 4 | 272
Waldenstrons macroglobulinemia 4 | 765
active Crohn's disease 4 | 922
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Digestive Tract 46 | 17,369
Endocrine System 46 | 18,159
Liver and Pancreas 46 | 16,750
Urinary Tract 45 | 16,678
Blood and immune system 44 | 16,909
Female tissues 44 | 17,400
Nervous System 44 | 16,725
Respiratory system 44 | 16,393
Skin and soft tissues 44 | 17,230
Male tissues 42 | 17,142
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 12 | 4,145
Kinase 9 | 634
Nuclear Receptor 3 | 48
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Process

animal organ regeneration 46 | 46
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.93014 835.0 246
Cytochrome b MT-CYB Tbio Non-IDG -3.77047 5856.5 134
Nicotinamide N-methyltransferase NNMT Tchem Enzyme -2.09313 121.9 268
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Proliferation marker protein Ki-67 MKI67 Tbio Non-IDG -2.50106 270.3 1434
Pyruvate kinase PKM PKM Tchem Kinase -3.15332 1424.2 749
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.36445 252.7 605
ADM ADM Tbio Non-IDG -3.27504 1889.0 381
Stromal cell-derived factor 1 CXCL12 Tbio Non-IDG -3.48446 3085.9 607
Placenta growth factor PGF Tclin Non-IDG -3.52194 3429.0 630