Development Level

Tbio 66 | 11,445
Tchem 10 | 1,598
Tclin 5 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal bone structure 3 | 187
impaired glucose tolerance 3 | 75
decreased body weight 2 | 161
hypoactivity 2 | 132
increased body weight 2 | 25
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
increased fasted circulating g... 2 | 76
tremors 2 | 39
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
abnormal spleen morphology 1 | 55
abnormal thymus morphology 1 | 7
anophthalmia 1 | 33
athymia 1 | 2
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased thermal nociceptive ... 1 | 2
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
eye hemorrhage 1 | 1
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
shortened ST segment 1 | 10
small superior vagus ganglion 1 | 74

Disease

Carcinoma 54 | 11,493
ovarian cancer 50 | 8,520
Cancer 43 | 2,499
osteosarcoma 43 | 7,950
psoriasis 38 | 6,694
lung cancer 35 | 4,740
glioblastoma 34 | 5,792
ependymoma 28 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
medulloblastoma, large-cell 28 | 6,241
Breast cancer 26 | 3,578
malignant mesothelioma 26 | 3,232
lung carcinoma 24 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
Astrocytoma, Pilocytic 22 | 3,081
interstitial cystitis 22 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
invasive ductal carcinoma 22 | 2,951
atypical teratoid / rhabdoid tumor 21 | 5,112
cystic fibrosis 21 | 1,696
adult high grade glioma 20 | 3,801
group 3 medulloblastoma 20 | 4,104
lung adenocarcinoma 20 | 2,716
pancreatic cancer 20 | 2,398
Short stature 19 | 531
non-small cell lung cancer 19 | 2,890
Intellectual disability 18 | 1,016
oligodendroglioma 18 | 2,850
Autosomal recessive predisposition 17 | 1,442
astrocytic glioma 17 | 2,597
breast carcinoma 17 | 1,638
Dull intelligence 16 | 645
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental deficiency 16 | 645
Poor school performance 16 | 645
tuberculosis 16 | 2,010
ulcerative colitis 16 | 1,819
ductal carcinoma in situ 15 | 1,745
Schizophrenia 14 | 1,160
pituitary cancer 14 | 1,972
Cognitive delay 13 | 608
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
Breast Neoplasms 12 | 445
Kidney cancer 12 | 2,613
Mammary Neoplasms 12 | 425
Muscle hypotonia 12 | 571
adrenocortical carcinoma 12 | 1,428
astrocytoma 12 | 1,146
group 4 medulloblastoma 12 | 1,855
Downward slant of palpebral fissure 11 | 158
Orbital separation excessive 11 | 244
colon cancer 11 | 1,478
cutaneous lupus erythematosus 11 | 1,057
diabetes mellitus 11 | 1,728
spina bifida 11 | 1,074
Blepharoptosis 10 | 231
Melanoma 10 | 711
Seizures 10 | 596
Ventricular Septal Defects 10 | 119
nasopharyngeal carcinoma 10 | 1,058
primary pancreatic ductal adenocarcinoma 10 | 1,109
primitive neuroectodermal tumor 10 | 3,035
subependymal giant cell astrocytoma 10 | 2,287
Cleft Palate 9 | 271
Congenital Epicanthus 9 | 177
Cryptorchidism 9 | 296
Epilepsy 9 | 792
Hypoplastic mandible condyle 9 | 275
Mandibular hypoplasia 9 | 275
Micrognathism 9 | 275
Short neck 9 | 140
Small head 9 | 374
Strabismus 9 | 270
active Crohn's disease 9 | 922
Acquired scoliosis 8 | 281
Anteverted nostril 8 | 191
Atopic dermatitis 8 | 952
Attention deficit hyperactivity disorder 8 | 278
Big calvaria 8 | 147
Cataract 8 | 297
Curvature of spine 8 | 282
Deafness 8 | 198
Hearing Loss, Partial 8 | 185
Increased head circumference 8 | 147
Increased size of cranium 8 | 147
Increased size of skull 8 | 147
Joint hyperflexibility 8 | 78
Lens Opacities 8 | 231
Long philtrum 8 | 137
Lung Neoplasms 8 | 232
Obesity 8 | 678
Rheumatoid arthritis 8 | 1,191
Sensorineural Hearing Loss (disorder) 8 | 284
Short nose 8 | 132
Small nose 8 | 132
medulloblastoma 8 | 720
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
pediatric high grade glioma 8 | 1,064

Tissue

Endocrine System 82 | 18,159
Digestive Tract 79 | 17,369
Female tissues 76 | 17,400
Liver and Pancreas 75 | 16,750
Male tissues 75 | 17,142
Skin and soft tissues 75 | 17,230
Blood and immune system 72 | 16,909
Nervous System 72 | 16,725
Urinary Tract 72 | 16,678
Respiratory system 68 | 16,393
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 44 | 12,091
Transcription Factor 25 | 1,400
Enzyme 7 | 4,145
Kinase 4 | 634
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GO Process

animal organ morphogenesis 83 | 83
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,3-N-acetylglucosaminyltransferase radical fringe RFNG Tdark Enzyme -0.37913 1.57 92
One cut domain family member 2 ONECUT2 Tbio Transcription Factor -2.25163 169.5 107
Cone-rod homeobox protein CRX Tbio Transcription Factor -2.44826 272.0 185
Four and a half LIM domains protein 1 FHL1 Tbio Non-IDG -2.46134 291.4 312
Friend leukemia integration 1 transcription factor FLI1 Tbio Transcription Factor -1.82504 66.8 454
Collagen alpha-1(XVIII) chain COL18A1 Tbio Non-IDG -3.18339 1561.4 433
Homeobox protein CDX-2 CDX2 Tbio Transcription Factor -2.91273 837.0 699
T-box transcription factor TBX3 TBX3 Tbio Transcription Factor -2.42253 255.6 328
Transmembrane protein 176B TMEM176B Tbio Non-IDG -1.58623 35.8 64
Pleckstrin homology-like domain family A member 2 PHLDA2 Tbio Non-IDG -1.73788 57.4 224