Development Level

Tchem 6 | 1,598
Tbio 3 | 11,445
Tclin 3 | 613

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
prolonged ST segment 1 | 36

Disease

Carcinoma 8 | 11,493
Hypertension 8 | 396
Kidney disease 7 | 430
osteosarcoma 7 | 7,950
diabetes mellitus 6 | 1,728
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
Atherosclerosis 5 | 291
Breast cancer 5 | 3,578
Cancer 5 | 2,499
Heart disease 5 | 306
Hypertensive disease 5 | 292
lung cancer 5 | 4,740
psoriasis 5 | 6,694
ulcerative colitis 5 | 1,819
Anemia 4 | 365
Autosomal recessive predisposition 4 | 1,442
Cerebrovascular disease 4 | 238
Coronary artery disease 4 | 268
Diabetic retinopathy 4 | 56
Hypertrophy, Left Ventricular 4 | 24
Left Ventricular Hypertrophy 4 | 47
Liver Cirrhosis, Experimental 4 | 769
Lung disease 4 | 142
atypical teratoid / rhabdoid tumor 4 | 5,112
cutaneous lupus erythematosus 4 | 1,057
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung carcinoma 4 | 2,843
medulloblastoma, large-cell 4 | 6,241
Albuminuria 3 | 21
Allanson Pantzar McLeod syndrome 3 | 4
Alzheimer's disease 3 | 658
Angioedema 3 | 38
Anuria 3 | 9
Asthma 3 | 385
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Congenital hypoplasia of lung 3 | 48
Depressive disorder 3 | 409
Diabetes Mellitus, Experimental 3 | 108
Diabetic Nephropathies 3 | 37
Diabetic Nephropathy 3 | 34
Fibrosis 3 | 44
Heart failure 3 | 162
Hyperaldosteronism 3 | 35
Hyperglycemia 3 | 137
Hypokalemia 3 | 52
Hypotension 3 | 82
Kidney Diseases 3 | 114
Kidney cancer 3 | 2,613
Maternal oligohydramnios 3 | 31
Multiple myeloma 3 | 1,332
Myocardial Infarction 3 | 151
Obesity 3 | 678
Oligohydramnios 3 | 52
Potter's facies 3 | 10
RENAL TUBULAR DYSGENESIS 3 | 4
Renal Insufficiency 3 | 90
Renal dysplasia 3 | 28
Respiratory Insufficiency 3 | 132
Respiratory function loss 3 | 121
Small head 3 | 374
Unipolar Depression 3 | 250
Widely patent fontanels and sutures 3 | 12
acute quadriplegic myopathy 3 | 1,158
cystic fibrosis 3 | 1,696
gastric carcinoma 3 | 807
glioblastoma 3 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
ovarian cancer 3 | 8,520
urothelial carcinoma 3 | 318
Adenoma 2 | 167
Allergic hypersensitivity disease 2 | 126
Atrial Fibrillation 2 | 124
Cardiovascular Diseases 2 | 59
Duchenne muscular dystrophy 2 | 601
Essential Hypertension 2 | 94
Focal glomerulosclerosis 2 | 37
IGA Glomerulonephritis 2 | 50
Kidney Failure 2 | 111
Lipid metabolism disorder 2 | 114
Liver Cirrhosis 2 | 181
Major Depressive Disorder 2 | 301
Melanoma 2 | 711
Mental Depression 2 | 333
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
Skin cancer 2 | 469
Vasculitis 2 | 80
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
esophageal adenocarcinoma 2 | 737
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Enzyme 10 | 4,145
Non-IDG 2 | 12,091

GO Process

angiotensin maturation 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mast cell carboxypeptidase A CPA3 Tchem Enzyme -1.72972 50.2 151
Angiotensin-converting enzyme 2 ACE2 Tchem Enzyme -3.00188 1129.3 720
Cathepsin Z CTSZ Tchem Enzyme -1.80363 70.2 233
Angiotensin-converting enzyme ACE Tclin Enzyme -4.52754 30363.8 643
Angiotensinogen AGT Tbio Non-IDG -3.24591 1711.3 695
Glutamyl aminopeptidase ENPEP Tchem Enzyme -2.81719 655.7 311
Neprilysin MME Tclin Enzyme -3.64168 4375.8 1505
Renin REN Tclin Enzyme -4.53626 33160.7 508
Chymase CMA1 Tchem Enzyme -3.03589 1121.1 278
Renin receptor ATP6AP2 Tbio Non-IDG -2.32908 192.9 236