Development Level

Tbio 148 | 11,445
Tchem 54 | 1,598
Tclin 16 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 18 | 979
embryonic lethality prior to t... 9 | 278
abnormal embryo size 7 | 220
preweaning lethality, incomple... 7 | 499
abnormal bone structure 6 | 187
abnormal heart morphology 6 | 162
enlarged heart 6 | 210
decreased lean body mass 5 | 135
increased total body fat amoun... 5 | 134
abnormal neural tube closure 4 | 46
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
pale yolk sac 4 | 25
abnormal forebrain development 3 | 20
abnormal locomotor behavior 3 | 24
abnormal pericardium morpholog... 3 | 26
cataract 3 | 92
decreased bone mineral density 3 | 126
decreased circulating triglyce... 3 | 79
decreased fasted circulating g... 3 | 65
decreased grip strength 3 | 116
decreased mean corpuscular vol... 3 | 79
embryonic growth retardation 3 | 106
hydrometra 3 | 53
impaired glucose tolerance 3 | 75
increased circulating alkaline... 3 | 122
increased lean body mass 3 | 172
increased red blood cell distr... 3 | 34
increased startle reflex 3 | 112
pallor 3 | 34
abnormal behavior 2 | 298
abnormal hindbrain development 2 | 16
abnormal lens morphology 2 | 81
abnormal midbrain development 2 | 20
abnormal retinal vasculature m... 2 | 27
decreased IgG1 level 2 | 8
decreased bone mineral content 2 | 151
decreased circulating chloride... 2 | 30
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased lymphocyte cell numb... 2 | 83
decreased red blood cell distr... 2 | 41
decreased spleen weight 2 | 10
impaired righting response 2 | 26
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating potassiu... 2 | 29
increased fasted circulating g... 2 | 76
increased hematocrit 2 | 46
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
short tibia 2 | 97
small seminal vesicle 2 | 10
small superior vagus ganglion 2 | 74
tremors 2 | 39
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal heart looping 1 | 5
abnormal lung morphology 1 | 26
abnormal neural tube morpholog... 1 | 12
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased neutrophil cell numb... 1 | 42
decreased pulmonary respirator... 1 | 5
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged stomach 1 | 2
enlarged uterus 1 | 11
impaired pupillary reflex 1 | 26
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
iris synechia 1 | 3
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
small thymus 1 | 16
thin ventricular wall 1 | 24
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 154 | 11,493
ovarian cancer 142 | 8,520
psoriasis 117 | 6,694
osteosarcoma 111 | 7,950
Cancer 104 | 2,499
glioblastoma 103 | 5,792
lung cancer 98 | 4,740
Breast cancer 84 | 3,578
medulloblastoma, large-cell 82 | 6,241
invasive ductal carcinoma 81 | 2,951
malignant mesothelioma 81 | 3,232
atypical teratoid / rhabdoid tumor 76 | 5,112
ependymoma 75 | 4,679
interstitial cystitis 74 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 74 | 2,955
lung adenocarcinoma 73 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 72 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 69 | 2,989
lung carcinoma 68 | 2,843
non-small cell lung cancer 67 | 2,890
pancreatic cancer 63 | 2,398
Astrocytoma, Pilocytic 62 | 3,081
adult high grade glioma 59 | 3,801
cystic fibrosis 58 | 1,696
breast carcinoma 55 | 1,638
ulcerative colitis 49 | 1,819
group 3 medulloblastoma 48 | 4,104
Kidney cancer 47 | 2,613
oligodendroglioma 47 | 2,850
ductal carcinoma in situ 43 | 1,745
pituitary cancer 43 | 1,972
tuberculosis 42 | 2,010
Breast Neoplasms 40 | 445
subependymal giant cell astrocytoma 40 | 2,287
Mammary Neoplasms 39 | 425
primitive neuroectodermal tumor 39 | 3,035
colon cancer 38 | 1,478
diabetes mellitus 38 | 1,728
gastric carcinoma 38 | 807
adrenocortical carcinoma 35 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,962
group 4 medulloblastoma 33 | 1,855
Hypertension 32 | 396
primary pancreatic ductal adenocarcinoma 32 | 1,109
astrocytic glioma 31 | 2,597
Schizophrenia 29 | 1,160
Vascular disease 29 | 319
juvenile dermatomyositis 28 | 1,187
Liver Cirrhosis, Experimental 26 | 769
Obesity 26 | 678
astrocytoma 26 | 1,146
cutaneous lupus erythematosus 26 | 1,057
Autosomal recessive predisposition 23 | 1,442
Kidney disease 23 | 430
pediatric high grade glioma 22 | 1,064
Bipolar Disorder 21 | 666
Hypertensive disease 21 | 292
Prostatic Neoplasms 21 | 495
nasopharyngeal carcinoma 21 | 1,058
Rheumatoid arthritis 20 | 1,191
aldosterone-producing adenoma 20 | 665
Heart disease 19 | 306
Melanoma 19 | 711
Multiple myeloma 19 | 1,332
acute quadriplegic myopathy 19 | 1,158
dermatomyositis 19 | 966
Arthritis 18 | 290
Atherosclerosis 18 | 291
Atopic dermatitis 18 | 952
Duchenne muscular dystrophy 18 | 601
Intellectual disability 18 | 1,016
Pick disease 18 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 510
fibroadenoma 18 | 559
spina bifida 18 | 1,074
Alzheimer's disease 17 | 658
Endometriosis 17 | 540
Down syndrome 16 | 499
Epilepsy 16 | 792
Lung Neoplasms 16 | 232
Seizures 16 | 596
active Crohn's disease 16 | 922
active ulcerative colitis 16 | 764
esophageal adenocarcinoma 16 | 737
Asthma 15 | 385
Liver cancer 15 | 604
Lung disease 15 | 142
Multiple Sclerosis 15 | 540
urothelial carcinoma 15 | 318
Adenocarcinoma 14 | 122
Coronary artery disease 14 | 268
Major Depressive Disorder 14 | 301
Neoplasm Invasiveness 14 | 161
mucosa-associated lymphoid tissue lymphoma 14 | 484
Cleft Palate 13 | 271
Dull intelligence 13 | 645
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Poor school performance 13 | 645

Tissue

Digestive Tract 217 | 17,369
Endocrine System 217 | 18,159
Liver and Pancreas 217 | 16,750
Female tissues 215 | 17,400
Skin and soft tissues 215 | 17,230
Urinary Tract 215 | 16,678
Blood and immune system 213 | 16,909
Male tissues 213 | 17,142
Respiratory system 211 | 16,393
Nervous System 210 | 16,725
Cardiovascular System 199 | 15,192

Target Family

Non-IDG 115 | 12,091
Enzyme 42 | 4,145
Transcription Factor 26 | 1,400
Kinase 25 | 634
GPCR 7 | 408
Epigenetic 2 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

angiogenesis 220 | 220
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Upstream-binding protein 1 UBP1 Tbio Transcription Factor -1.69641 47.4 194
Histone-lysine N-methyltransferase SETD2 SETD2 Tchem Epigenetic -2.83266 645.3 214
Collagen alpha-1(VIII) chain COL8A1 Tbio Non-IDG -1.31054 16.6 116
Tumor necrosis factor ligand superfamily member 12 TNFSF12 Tbio Non-IDG -2.49751 362.7 413
ETS domain-containing protein Elk-3 ELK3 Tbio Transcription Factor -0.17124 0.86 225
Neurexin-3-beta NRXN3 Tbio Non-IDG -1.34072 34.8 172
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Ephrin type-B receptor 1 EPHB1 Tchem Kinase -1.70013 52.0 389
Ephrin type-B receptor 4 EPHB4 Tchem Kinase -2.26622 206.3 514