Development Level

Tbio 136 | 10,625
Tchem 66 | 1,890
Tclin 14 | 602
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 13 | 633
embryonic lethality prior to t... 6 | 187
preweaning lethality, incomple... 6 | 260
abnormal embryo size 5 | 112
abnormal neural tube closure 4 | 37
decreased grip strength 4 | 123
enlarged heart 4 | 111
abnormal behavior 3 | 226
abnormal bone structure 3 | 131
abnormal forebrain development 3 | 18
abnormal hindbrain development 3 | 24
abnormal midbrain development 3 | 22
decreased circulating alanine ... 3 | 53
decreased mean corpuscular vol... 3 | 50
embryonic lethality prior to o... 3 | 148
increased circulating HDL chol... 3 | 63
increased circulating alkaline... 3 | 119
increased or absent threshold ... 3 | 128
pale yolk sac 3 | 12
abnormal heart morphology 2 | 51
absent heartbeat 2 | 6
cataract 2 | 26
decreased bone mineral content 2 | 157
decreased circulating alkaline... 2 | 41
decreased circulating chloride... 2 | 32
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased fasted circulating g... 2 | 49
decreased hemoglobin content 2 | 53
decreased lean body mass 2 | 195
decreased spleen weight 2 | 13
decreased total body fat amoun... 2 | 186
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased circulating calcium ... 2 | 32
increased fasted circulating g... 2 | 68
increased hematocrit 2 | 36
increased lean body mass 2 | 107
increased mean corpuscular vol... 2 | 91
increased total body fat amoun... 2 | 57
increased vertical activity 2 | 18
lethargy 2 | 5
narrow eye opening 2 | 15
pallor 2 | 13
short tibia 2 | 82
tremors 2 | 34
abnormal QRS complex 1 | 25
abnormal allantois morphology 1 | 3
abnormal body wall morphology 1 | 7
abnormal cornea morphology 1 | 24
abnormal embryo turning 1 | 15
abnormal eye morphology 1 | 38
abnormal gait 1 | 51
abnormal heart left ventricle ... 1 | 20
abnormal iris morphology 1 | 12
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal lung morphology 1 | 15
abnormal neural tube morpholog... 1 | 8
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal skin appearance 1 | 8
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal tail bud morphology 1 | 6
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
cleft palate 1 | 6
corneal opacity 1 | 25
decreased IgG1 level 1 | 4
decreased Ly6C high monocyte n... 1 | 18
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating calcium ... 1 | 33
decreased circulating sodium l... 1 | 18
decreased eosinophil cell numb... 1 | 41
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased monocyte cell number 1 | 28
decreased pulmonary respirator... 1 | 4
embryonic growth retardation 1 | 28
enlarged stomach 1 | 2
hydrometra 1 | 13
impaired righting response 1 | 19
increased circulating alanine ... 1 | 11
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased grip strength 1 | 83
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
prenatal lethality prior to he... 1 | 64
small thymus 1 | 11
straub tail 1 | 26
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

ovarian cancer 140 | 8,492
psoriasis 116 | 6,685
osteosarcoma 109 | 7,933
Cancer 101 | 2,346
glioblastoma 93 | 5,572
lung cancer 93 | 4,473
medulloblastoma, large-cell 82 | 6,234
invasive ductal carcinoma 81 | 2,950
malignant mesothelioma 78 | 3,163
interstitial cystitis 75 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 74 | 2,956
lung adenocarcinoma 73 | 2,714
intraductal papillary-mucinous neoplasm (IPMN) 72 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 69 | 2,988
atypical teratoid / rhabdoid tumor 68 | 4,369
Breast cancer 66 | 3,099
lung carcinoma 66 | 2,844
pilocytic astrocytoma 62 | 3,086
non-small cell lung cancer 60 | 2,798
pancreatic cancer 59 | 2,300
cystic fibrosis 58 | 1,670
ulcerative colitis 54 | 2,087
breast carcinoma 53 | 1,614
pediatric high grade glioma 51 | 2,712
oligodendroglioma 48 | 2,849
Carcinoma 43 | 2,147
ductal carcinoma in situ 43 | 1,745
pituitary cancer 42 | 1,972
posterior fossa group A ependymoma 42 | 1,511
gastric carcinoma 40 | 832
primitive neuroectodermal tumor 40 | 3,031
subependymal giant cell astrocytoma 40 | 2,287
Mammary Neoplasms 39 | 410
colon cancer 38 | 1,475
diabetes mellitus 37 | 1,663
adrenocortical carcinoma 35 | 1,427
primary pancreatic ductal adenocarcinoma 35 | 1,271
tuberculosis 33 | 1,563
group 3 medulloblastoma 31 | 2,254
adult high grade glioma 30 | 2,148
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,795
astrocytoma 29 | 1,493
group 4 medulloblastoma 29 | 1,875
juvenile dermatomyositis 28 | 1,189
sonic hedgehog group medulloblastoma 28 | 1,482
Vascular disease 27 | 281
ependymoma 27 | 2,514
astrocytic glioma 26 | 2,241
cutaneous lupus erythematosus 25 | 1,056
posterior fossa group B ependymoma 25 | 1,530
Hypertension 24 | 293
Kidney disease 22 | 397
nasopharyngeal carcinoma 21 | 1,056
Prostatic Neoplasms 20 | 471
Rheumatoid Arthritis 20 | 1,171
aldosterone-producing adenoma 20 | 664
Alzheimer's disease 19 | 644
Multiple myeloma 19 | 1,328
Obesity 19 | 616
Pick disease 19 | 1,893
acute quadriplegic myopathy 19 | 1,157
dermatomyositis 19 | 967
Atopic dermatitis 18 | 944
Duchenne muscular dystrophy 18 | 602
Heart disease 18 | 279
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 499
fibroadenoma 18 | 557
non-small cell lung carcinoma 18 | 413
Atherosclerosis 17 | 275
Endometriosis 17 | 535
spina bifida 17 | 1,064
Arthritis 16 | 248
Hypertensive disease 16 | 193
Lung Neoplasms 16 | 171
active Crohn's disease 16 | 918
medulloblastoma 16 | 1,524
Down syndrome 15 | 548
atypical teratoid/rhabdoid tumor 15 | 1,095
esophageal adenocarcinoma 15 | 737
glioblastoma multiforme 15 | 347
urothelial carcinoma 15 | 318
Asthma 14 | 349
Liver disease 14 | 219
Lung disease 14 | 136
mucosa-associated lymphoid tissue lymphoma 14 | 480
Adenocarcinoma 13 | 115
IGA Glomerulonephritis 13 | 454
Multiple Sclerosis 13 | 498
hepatocellular carcinoma 13 | 550
Autistic Disorder 12 | 320
Colorectal Neoplasms 12 | 217
Coronary artery disease 12 | 240
Diabetes Mellitus, Experimental 12 | 106
Myocardial Ischemia 12 | 169
Neoplasm Invasiveness 12 | 127
Polycystic Ovary Syndrome 12 | 335
Reperfusion Injury 12 | 84
Stomach Neoplasms 12 | 282
inflammatory breast cancer 12 | 404
non primary Sjogren syndrome sicca 12 | 840

Tissue

Cardiovascular System 216 | 17,958
Digestive Tract 216 | 18,473
Female tissues 216 | 18,647
Male tissues 216 | 17,969
Nervous System 216 | 18,561
Urinary Tract 216 | 18,444
Blood and immune system 215 | 17,995
Endocrine System 215 | 18,512
Skin and soft tissues 215 | 18,115
Liver and Pancreas 214 | 18,136
Respiratory system 214 | 17,484

Target Family

Non-IDG 112 | 11,969
Enzyme 43 | 4,146
Transcription Factor 26 | 1,400
Kinase 25 | 634
GPCR 7 | 408
Epigenetic 2 | 242
Ion Channel 1 | 341
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

angiogenesis 218 | 218
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor Ovo-like 2 OVOL2 Tbio Transcription Factor -1.12872 15.5 91
ATPase inhibitor, mitochondrial ATPIF1 Tbio Enzyme -2.17521 137.1 147
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.05927 116.0 218
NADPH oxidase 5 NOX5 Tbio Enzyme -1.78802 71.4 163
Zinc finger protein 304 ZNF304 Tbio Transcription Factor -0.82181 1.86 13
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.82355 7.27 72
Aminopeptidase N ANPEP Tchem Enzyme -3.26833 1759.9 972
Ephrin type-B receptor 4 EPHB4 Tchem Kinase -2.22611 184.7 435
Epidermal growth factor-like protein 7 EGFL7 Tchem Non-IDG -1.73134 65.0 174
Hypoxia-inducible factor 3-alpha HIF3A Tbio Non-IDG -2.50469 313.9 193