Development Level

Tbio 4 | 11,445
Tclin 4 | 613
Tchem 3 | 1,598

IMPC Phenotype

abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased circulating choleste... 2 | 66
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal male genitalia morpho... 1 | 3
abnormal placenta size 1 | 20
abnormal tail bud morphology 1 | 8
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
cardiovascular system phenotyp... 1 | 36
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating phosphat... 1 | 27
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
oligodactyly 1 | 1
pale yolk sac 1 | 25
pallor 1 | 34
polydactyly 1 | 7
preweaning lethality, complete... 1 | 979
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small kidney 1 | 16
small superior vagus ganglion 1 | 74

Disease

Prostatic Neoplasms 7 | 495
ovarian cancer 6 | 8,520
Carcinoma 5 | 11,493
Polycystic ovary syndrome 5 | 360
psoriasis 5 | 6,694
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Cryptorchidism 4 | 296
Endometriosis 4 | 540
Hyperandrogenism 4 | 34
Hypospadias 4 | 53
Infertility 4 | 188
Prostate cancer 4 | 175
Pseudohermaphroditism 4 | 16
ductal carcinoma in situ 4 | 1,745
invasive ductal carcinoma 4 | 2,951
medulloblastoma, large-cell 4 | 6,241
Amenorrhea 3 | 58
Cancer 3 | 2,499
Carcinoma, Hepatocellular 3 | 228
Congenital adrenal hyperplasia 3 | 73
Cushing's syndrome 3 | 48
Gynecomastia 3 | 64
Liver Cirrhosis, Experimental 3 | 769
Liver carcinoma 3 | 240
Male Pseudohermaphroditism 3 | 19
Osteoporosis 3 | 363
Penile hypospadias 3 | 106
Pick disease 3 | 1,894
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Abnormality of metabolism/homeostasis 2 | 134
Absence of secondary sex characteristics 2 | 22
Adrenal Hyperplasia, Congenital 2 | 9
Adrenal hyperplasia 2 | 13
Adrenocorticotropic hormone excess 2 | 5
Adrenogenital Syndrome 2 | 6
Alcoholic Intoxication, Chronic 2 | 289
Ambiguous Genitalia 2 | 24
Ambiguous genitalia, male 2 | 9
Astrocytoma, Pilocytic 2 | 3,081
Benign prostatic hyperplasia 2 | 7
Bifid scrotum 2 | 16
Congenital hypoplasia of penis 2 | 176
Decreased fertility in females 2 | 20
Decreased male fertility 2 | 7
Delayed Puberty 2 | 97
Delayed bone age 2 | 136
Elevated follicle stimulating hormone 2 | 15
Elevated luteinizing hormone 2 | 14
Enlarged polycystic ovaries 2 | 10
Generalized hyperpigmentation 2 | 22
Hyperaldosteronism 2 | 35
Hypercortisolism 2 | 8
Hyperkalemia 2 | 17
Hypertension 2 | 396
Hypospadias, perineal 2 | 5
Increased circulating ACTH level 2 | 8
Infantile uterus 2 | 23
Kidney cancer 2 | 2,613
Lipid metabolism disorder 2 | 114
Low to undetectable plasma cortisol 2 | 12
Male Patterned Baldness 2 | 2
Non-alcoholic Fatty Liver Disease 2 | 42
Parkinson's disease 2 | 392
Premature ovarian failure 2 | 65
Primary physiologic amenorrhea 2 | 55
Short stature 2 | 531
Small testicle 2 | 75
Urogenital sinus anomaly 2 | 15
adult high grade glioma 2 | 3,801
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormal sex determination 1 | 11
Female external genitalia in males 1 | 13
Hypoplasia of vagina 1 | 14
Paranoia 1 | 20
Paranoid Disorders 1 | 8
Rudimentary vagina 1 | 14
Sex reversal 1 | 10
menstrual periods stopped for over 6 months 1 | 13

Tissue

Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Digestive Tract 10 | 17,369
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Blood and immune system 9 | 16,909
Cardiovascular System 6 | 15,192

Target Family

Enzyme 9 | 4,145
Non-IDG 2 | 12,091

GO Process

androgen biosynthetic process 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 HSD3B1 Tchem Enzyme -2.62147 370.7 267
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369
Polyprenol reductase SRD5A3 Tbio Enzyme -1.38816 25.5 72
Testosterone 17-beta-dehydrogenase 3 HSD17B3 Tchem Enzyme -2.03781 102.2 140
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 HSD3B2 Tclin Enzyme -2.06512 109.2 126
17-beta-hydroxysteroid dehydrogenase type 6 HSD17B6 Tbio Enzyme -3.08175 1116.1 80
3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 Tclin Enzyme 0.00000 195
3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 Tclin Enzyme -1.97806 90.7 131
Protein Wnt-4 WNT4 Tbio Non-IDG -2.35896 227.8 288