Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal heart morphology 1 | 162
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
enlarged heart 1 | 210
increased monocyte cell number 1 | 63

Disease

Cancer 4 | 2,499
Carcinoma 3 | 11,493
ductal carcinoma in situ 3 | 1,745
invasive ductal carcinoma 3 | 2,951
psoriasis 3 | 6,694
Gastroenteritis 2 | 41
Osteopetrosis 2 | 43
Salmonellosis 2 | 42
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
Abnormal cortical bone morphology 1 | 22
Abnormality of the backbone 1 | 4
Abnormality of the clavicle 1 | 14
Abnormality of the vertebral column 1 | 4
Absent anterior chamber of eye 1 | 1
Acute cystitis 1 | 35
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Atrophic iris 1 | 2
Barrel chest 1 | 12
Brucellosis 1 | 24
Camurati-Engelmann disease 1 | 6
Coats disease 1 | 13
Collapse of vertebra 1 | 14
Common variable immunodeficiency 1 | 101
Compression fracture of vertebral column 1 | 14
Congenital retinal fold 1 | 3
Craniodiaphyseal dysplasia 1 | 3
Craniofacial hyperostosis 1 | 11
Diaphyseal thickening 1 | 11
Diffuse, symmetrical osteosclerosis 1 | 5
Enlargement of craniofacial bones 1 | 11
Exudative vitreoretinopathy 1 | 15
Exudative vitreoretinopathy 1 1 | 5
Facial paralysis 1 | 18
Familial Exudative Vitreoretinopathy 1 | 5
Flat forehead 1 | 5
Fractures, Bone 1 | 13
Glioma 1 | 74
Hyperostosis 1 | 18
Hyperostosis of cranial vault 1 | 7
Hypertrophy of craniofacial bones 1 | 11
Idiopathic juvenile osteoporosis 1 | 1
Increased bone density in skeletal bones 1 | 5
Increased thickness of cranium 1 | 17
Isolated polycystic liver disease 1 | 3
Juvenile osteoporosis 1 | 4
Kyphoscoliosis deformity of spine 1 | 60
Leukemia, Myeloid, Acute 1 | 105
Leukocoria 1 | 10
Malocclusion 1 | 57
Maxillary torus 1 | 2
Melioidosis 1 | 17
Metacarpal diaphyseal endosteal sclerosis 1 | 1
Metaphyseal widening 1 | 22
Metatarsal diaphyseal endosteal sclerosis 1 | 1
Microphthalmia 1 | 76
Mild Mental Retardation 1 | 70
Multiple renal cysts 1 | 5
Osteopoikilosis 1 | 6
Osteoporosis with pseudoglioma 1 | 1
Osteoporosis, Juvenile 1 | 4
Osteosclerosis 1 | 31
Pathological fracture 1 | 20
Peripheral retinal avascularization 1 | 2
Phthisis bulbi 1 | 5
Pilomatrixoma 1 | 12
Platyspondyly 1 | 56
Polycystic liver disease 1 | 16
Posterior Vitreous Detachment 1 | 2
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1 | 25
Prominent midpalatal ridge (torus palatinus) 1 | 2
Pulmonary alveolar proteinosis 1 | 15
Reduced visual acuity 1 | 63
Retinal Neovascularization 1 | 4
Retinopathy of prematurity 1 | 22
SOST-related sclerosing bone dysplasia 1 | 8
Sebaceous Gland Neoplasms 1 | 1
Shigellosis 1 | 21
Subcapsular cataract 1 | 5
Thick craniofacial bones 1 | 11
Thickened calvaria 1 | 17
Thickened cortex of long bones 1 | 4
Torus palatinus 1 | 2
Typhoid fever 1 | 22
Van Buchem disease 1 | 2
Vitreoretinal abnormalities 1 | 2
Vitreous Hemorrhage 1 | 6
Worth disease 1 | 1
abnormal growth 1 | 26
osteoporosis-pseudoglioma syndrome 1 | 9

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400

GO Process

anatomical structure regressio... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
Endosialin CD248 Tbio Non-IDG -3.07620 1180.8 253
Low-density lipoprotein receptor-related protein 5 LRP5 Tbio Non-IDG -3.10429 1247.5 302
Lymphoid enhancer-binding factor 1 LEF1 Tchem Transcription Factor -2.60971 375.2 591