Development Level

Tbio 108 | 11,651
Tdark 13 | 6,593
Tchem 5 | 1,388
Tclin 4 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal embryo size 4 | 220
increased mean corpuscular vol... 4 | 92
preweaning lethality, incomple... 4 | 499
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
abnormal skin coloration 2 | 25
decreased circulating alkaline... 2 | 46
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
enlarged heart 2 | 210
hyperactivity 2 | 148
hypoactivity 2 | 132
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal pancreas morphology 1 | 13
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
female infertility 1 | 60
hemorrhage 1 | 23
increased CD4-positive, alpha ... 1 | 4
increased T cell number 1 | 6
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
no spontaneous movement 1 | 1
pallor 1 | 34
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58
thick ventricular wall 1 | 7
thrombocytopenia 1 | 56

Disease

Carcinoma 72 | 11,493
ovarian cancer 52 | 8,520
psoriasis 50 | 6,694
osteosarcoma 48 | 7,950
Cancer 42 | 2,499
glioblastoma 38 | 5,792
medulloblastoma, large-cell 35 | 6,241
Breast cancer 34 | 3,578
atypical teratoid / rhabdoid tumor 32 | 5,112
lung cancer 32 | 4,740
lung adenocarcinoma 29 | 2,716
group 3 medulloblastoma 28 | 4,104
invasive ductal carcinoma 27 | 2,951
non-small cell lung cancer 27 | 2,890
malignant mesothelioma 26 | 3,232
lung carcinoma 25 | 2,843
breast carcinoma 24 | 1,638
pancreatic cancer 24 | 2,398
ductal carcinoma in situ 23 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
interstitial cystitis 22 | 2,312
pituitary cancer 22 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
Astrocytoma, Pilocytic 20 | 3,081
ependymoma 20 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
primitive neuroectodermal tumor 19 | 3,035
adult high grade glioma 18 | 3,801
cystic fibrosis 18 | 1,696
diabetes mellitus 18 | 1,728
adrenocortical carcinoma 17 | 1,428
group 4 medulloblastoma 16 | 1,855
Autosomal recessive predisposition 13 | 1,442
oligodendroglioma 13 | 2,850
Cleft Palate 12 | 271
spina bifida 12 | 1,074
tuberculosis 12 | 2,010
Acquired metabolic disease 11 | 336
Atopic dermatitis 11 | 952
Muscle hypotonia 11 | 571
Pick disease 11 | 1,894
pediatric high grade glioma 11 | 1,064
ulcerative colitis 11 | 1,819
Breast Neoplasms 10 | 445
Kidney cancer 10 | 2,613
Mammary Neoplasms 10 | 425
Rheumatoid arthritis 10 | 1,191
Sensorineural Hearing Loss (disorder) 10 | 284
astrocytic glioma 10 | 2,597
esophageal adenocarcinoma 10 | 737
subependymal giant cell astrocytoma 10 | 2,287
Bipolar Disorder 9 | 666
Broad flat nasal bridge 9 | 236
Constipation 9 | 181
Intellectual disability 9 | 1,016
Multiple Sclerosis 9 | 540
Nasal bridge wide 9 | 236
Obesity 9 | 678
astrocytoma 9 | 1,146
colon cancer 9 | 1,478
fibroadenoma 9 | 559
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
primary pancreatic ductal adenocarcinoma 9 | 1,109
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Schizophrenia 8 | 1,160
Short stature 8 | 531
acute quadriplegic myopathy 8 | 1,158
Carcinoma, Hepatocellular 7 | 228
Cognitive delay 7 | 608
Concave bridge of nose 7 | 195
Craniofacial Abnormalities 7 | 151
Cryptorchidism 7 | 296
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Dyschezia 7 | 135
Global developmental delay 7 | 608
Liver carcinoma 7 | 240
Mental and motor retardation 7 | 608
cutaneous lupus erythematosus 7 | 1,057
non primary Sjogren syndrome sicca 7 | 891
sonic hedgehog group medulloblastoma 7 | 467
Acquired scoliosis 6 | 281
Adenoma 6 | 167
Cleft Lip 6 | 141
Congenital Epicanthus 6 | 177
Curvature of spine 6 | 282
Deafness 6 | 198
Depressive disorder 6 | 409
Epilepsy 6 | 792
Hearing Loss, Partial 6 | 185
Liver Cirrhosis, Experimental 6 | 769
Mental Depression 6 | 333
Uranostaphyloschisis 6 | 167
juvenile dermatomyositis 6 | 1,187
medulloblastoma 6 | 720
posterior fossa group A ependymoma 6 | 468

Tissue

Endocrine System 124 | 18,159
Skin and soft tissues 117 | 17,230
Digestive Tract 115 | 17,369
Female tissues 115 | 17,400
Blood and immune system 113 | 16,909
Male tissues 110 | 17,142
Liver and Pancreas 106 | 16,750
Urinary Tract 105 | 16,678
Nervous System 102 | 16,725
Respiratory system 101 | 16,393
Cardiovascular System 83 | 15,192

Target Family

Transcription Factor 65 | 1,400
Non-IDG 47 | 12,091
Enzyme 8 | 4,145
GPCR 4 | 408
Epigenetic 3 | 242
Kinase 2 | 634
TF/Epigenetic 1 | 38

GO Process

anatomical structure morphogen... 130 | 130
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
39S ribosomal protein L40, mitochondrial MRPL40 Tbio Non-IDG -0.92179 8.33 105
Nuclear factor erythroid 2-related factor 1 NFE2L1 Tbio Transcription Factor -1.57346 40.9 157
Lymphatic vessel endothelial hyaluronic acid receptor 1 LYVE1 Tbio Non-IDG -2.77184 557.5 586
Calcipressin-3 RCAN3 Tbio Non-IDG -0.77232 6.75 203
Dickkopf-like protein 1 DKKL1 Tbio Non-IDG -2.20166 148.4 140
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.94674 87.1 452
POU domain, class 5, transcription factor 1 POU5F1 Tbio Transcription Factor -3.31332 2140.4 983
Forkhead box protein S1 FOXS1 Tdark Transcription Factor -0.43453 3.53 53
Ephrin-B2 EFNB2 Tbio Non-IDG -2.45068 288.9 381
Forkhead box protein K1 FOXK1 Tbio Transcription Factor -2.42390 266.0 150