Development Level

Tbio 75 | 10,625
Tchem 7 | 1,890
Tdark 5 | 7,003
Tclin 4 | 602

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal embryo size 3 | 112
decreased body length 2 | 108
decreased circulating alkaline... 2 | 41
decreased grip strength 2 | 123
increased circulating alkaline... 2 | 119
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
preweaning lethality, incomple... 2 | 260
abnormal heart morphology 1 | 51
abnormal posture 1 | 5
abnormal skin morphology 1 | 23
abnormal tail morphology 1 | 17
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
decreased circulating alanine ... 1 | 53
decreased circulating iron lev... 1 | 25
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 19
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
decreased startle reflex 1 | 48
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
hyperactivity 1 | 108
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased cellular hemoglobin ... 1 | 2
increased mean corpuscular hem... 1 | 25
increased red blood cell distr... 1 | 21
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
male infertility 1 | 62
no spontaneous movement 1 | 1
small adrenal glands 1 | 15
small testis 1 | 37
straub tail 1 | 26

Disease

osteosarcoma 40 | 7,933
ovarian cancer 40 | 8,484
psoriasis 36 | 6,685
Cancer 29 | 2,346
glioblastoma 29 | 5,572
medulloblastoma, large-cell 27 | 6,234
lung cancer 26 | 4,466
Breast cancer 25 | 3,094
lung adenocarcinoma 24 | 2,713
atypical teratoid / rhabdoid tumor 22 | 4,369
invasive ductal carcinoma 22 | 2,950
lung carcinoma 21 | 2,844
non-small cell lung cancer 21 | 2,798
breast carcinoma 20 | 1,614
malignant mesothelioma 20 | 3,162
pancreatic cancer 20 | 2,300
ductal carcinoma in situ 19 | 1,745
interstitial cystitis 18 | 2,299
pituitary cancer 18 | 1,972
group 4 medulloblastoma 17 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
primitive neuroectodermal tumor 16 | 3,031
adrenocortical carcinoma 15 | 1,427
group 3 medulloblastoma 15 | 2,254
pediatric high grade glioma 15 | 2,712
pilocytic astrocytoma 15 | 3,086
cystic fibrosis 13 | 1,665
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
diabetes mellitus 11 | 1,663
Pick disease 10 | 1,893
adult high grade glioma 10 | 2,148
oligodendroglioma 10 | 2,849
posterior fossa group A ependymoma 10 | 1,511
spina bifida 10 | 1,064
subependymal giant cell astrocytoma 10 | 2,287
ulcerative colitis 10 | 2,087
Atopic dermatitis 9 | 944
Carcinoma 9 | 2,147
esophageal adenocarcinoma 9 | 737
primary pancreatic ductal adenocarcinoma 9 | 1,271
Acquired metabolic disease 8 | 267
Cleft palate 8 | 125
Rheumatoid Arthritis 8 | 1,160
DiGeorge syndrome 7 | 46
acute quadriplegic myopathy 7 | 1,157
astrocytoma 7 | 1,493
cutaneous lupus erythematosus 7 | 1,056
posterior fossa group B ependymoma 7 | 1,530
tuberculosis 7 | 1,557
Cleft Lip 6 | 91
Liver carcinoma 6 | 217
Mammary Neoplasms 6 | 410
astrocytic glioma 6 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
colon cancer 6 | 1,475
fibroadenoma 6 | 557
gastric carcinoma 6 | 832
juvenile dermatomyositis 6 | 1,189
non primary Sjogren syndrome sicca 6 | 840
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
Adenoma 5 | 165
Craniofacial Abnormalities 5 | 147
Duchenne muscular dystrophy 5 | 602
Multiple Sclerosis 5 | 498
Velocardiofacial syndrome 5 | 45
acute myeloid leukemia 5 | 780
aldosterone-producing adenoma 5 | 664
atypical teratoid/rhabdoid tumor 5 | 1,095
ependymoma 5 | 2,514
hepatocellular carcinoma 5 | 532
medulloblastoma 5 | 1,524
nasopharyngeal carcinoma 5 | 1,056
nephrosclerosis 5 | 329
non-small cell lung carcinoma 5 | 413
Colorectal Neoplasms 4 | 217
Kidney disease 4 | 396
Multiple myeloma 4 | 1,327
Obesity 4 | 616
Sensorineural hearing loss 4 | 107
inflammatory breast cancer 4 | 404
mucosa-associated lymphoid tissue lymphoma 4 | 480
sarcoidosis 4 | 358
sonic hedgehog group medulloblastoma 4 | 1,482
tuberculosis and treatment for 6 months 4 | 686
Autistic Disorder 3 | 320
Congenital Heart Defects 3 | 37
Down syndrome 3 | 548
Endometriosis 3 | 535
Epilepsy 3 | 346
Holoprosencephaly 3 | 52
Hypothyroidism 3 | 89
Intellectual disability 3 | 573
Parkinson's disease 3 | 364
active ulcerative colitis 3 | 477
chronic lymphosyte leukemia 3 | 232
chronic rhinosinusitis 3 | 512
pancreatic carcinoma 3 | 567
primary Sjogren syndrome 3 | 789
progressive supranuclear palsy 3 | 674

Tissue

Cardiovascular System 89 | 17,958
Endocrine System 89 | 18,512
Female tissues 89 | 18,647
Nervous System 89 | 18,561
Skin and soft tissues 89 | 18,115
Digestive Tract 88 | 18,473
Male tissues 88 | 17,969
Blood and immune system 87 | 17,995
Urinary Tract 87 | 18,444
Liver and Pancreas 86 | 18,136
Respiratory system 84 | 17,484

Target Family

Non-IDG 46 | 11,971
Transcription Factor 28 | 1,400
Enzyme 8 | 4,146
GPCR 4 | 406
Epigenetic 3 | 242
Kinase 1 | 634
TF/Epigenetic 1 | 38

GO Process

anatomical structure morphogen... 91 | 91
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sex comb on midleg-like protein 2 SCML2 Tbio Epigenetic -1.13986 13.7 93
Glypican-3 GPC3 Tbio Non-IDG -2.85848 794.8 523
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.65303 525.6 142
Homeobox protein Hox-B5 HOXB5 Tbio Transcription Factor -1.79865 63.7 162
Homeobox protein Hox-A1 HOXA1 Tbio Transcription Factor -1.95847 92.9 260
Homeobox protein goosecoid-2 GSC2 Tbio Transcription Factor -1.23130 18.9 44
Syncytin-1 ERVW-1 Tbio Non-IDG -3.60744 3712.1 143
Fibroblast growth factor 18 FGF18 Tbio Non-IDG -1.83412 76.6 133
POU domain, class 5, transcription factor 1 POU5F1 Tbio Transcription Factor -3.28204 1980.8 817
Clathrin heavy chain 2 CLTCL1 Tbio Non-IDG -1.26936 21.4 27