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Target Filters...

Development Level

Tbio 50 | 10,625
Tchem 19 | 1,890
Tclin 5 | 602
Tdark 3 | 7,003

IMPC Term

preweaning lethality, complete... 11 | 633
embryonic lethality prior to t... 5 | 187
embryonic lethality prior to o... 4 | 148
abnormal embryo size 3 | 112
embryonic growth retardation 3 | 28
anophthalmia 2 | 20
abnormal craniofacial morpholo... 1 | 12
abnormal forebrain morphology 1 | 4
abnormal head shape 1 | 4
abnormal hindbrain morphology 1 | 2
abnormal midbrain morphology 1 | 2
abnormal neural tube closure 1 | 37
abnormal placenta morphology 1 | 4
abnormal placenta size 1 | 10
abnormal skin coloration 1 | 18
decreased body length 1 | 108
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating glucose ... 1 | 121
edema 1 | 11
improved glucose tolerance 1 | 56
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
microphthalmia 1 | 15
pallor 1 | 13
prenatal lethality 1 | 16
urinary bladder obstruction 1 | 2

Disease

ovarian cancer 54 | 8,492
psoriasis 38 | 6,685
lung cancer 37 | 4,473
osteosarcoma 32 | 7,933
glioblastoma 31 | 5,572
Multiple myeloma 28 | 1,328
medulloblastoma, large-cell 21 | 6,234
Cancer 20 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
Breast cancer 17 | 3,099
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
invasive ductal carcinoma 17 | 2,950
non-small cell lung cancer 17 | 2,798
HIV Infections 15 | 100
malignant mesothelioma 15 | 3,163
pediatric high grade glioma 15 | 2,712
lung adenocarcinoma 14 | 2,714
Waldenstrons macroglobulinemia 13 | 765
adrenocortical carcinoma 13 | 1,427
atypical teratoid / rhabdoid tumor 13 | 4,369
dermatomyositis 12 | 967
pancreatic cancer 12 | 2,300
primitive neuroectodermal tumor 12 | 3,031
group 3 medulloblastoma 11 | 2,254
posterior fossa group A ependymoma 11 | 1,511
IGA Glomerulonephritis 10 | 454
breast carcinoma 10 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
Atopic dermatitis 9 | 944
Endometriosis 9 | 535
colon cancer 9 | 1,475
astrocytoma 8 | 1,493
ductal carcinoma in situ 8 | 1,745
non primary Sjogren syndrome sicca 8 | 840
primary Sjogren syndrome 8 | 789
Pick disease 7 | 1,893
diabetes mellitus 7 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
oligodendroglioma 7 | 2,849
astrocytic glioma 6 | 2,241
ependymoma 6 | 2,514
esophageal adenocarcinoma 6 | 737
interstitial cystitis 6 | 2,299
nasopharyngeal carcinoma 6 | 1,056
sonic hedgehog group medulloblastoma 6 | 1,482
ulcerative colitis 6 | 2,087
Mantle cell lymphoma 5 | 20
active Crohn's disease 5 | 918
acute quadriplegic myopathy 5 | 1,157
atypical teratoid/rhabdoid tumor 5 | 1,095
lung carcinoma 5 | 2,844
medulloblastoma 5 | 1,524
Squamous cell carcinoma of esophagus 4 | 82
acute myeloid leukemia 4 | 785
cutaneous lupus erythematosus 4 | 1,056
juvenile dermatomyositis 4 | 1,189
pilocytic astrocytoma 4 | 3,086
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,271
subependymal giant cell astrocytoma 4 | 2,287
Mammary Neoplasms, Experimental 3 | 150
Osteoporosis 3 | 259
Peripheral Neuropathy 3 | 303
Polycystic Ovary Syndrome 3 | 335
inflammatory breast cancer 3 | 404
progressive supranuclear palsy 3 | 674
tuberculosis 3 | 1,563
Acquired metabolic disease 2 | 267
Alzheimer's disease 2 | 644
Animal Mammary Neoplasms 2 | 136
Carcinoma of colon 2 | 32
Colorectal Neoplasms 2 | 217
Diffuse large B-cell lymphoma 2 | 42
Duchenne muscular dystrophy 2 | 602
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 2 | 4
Mammary Neoplasms 2 | 410
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Parkinson's disease 2 | 364
Pick's disease 2 | 14
Rheumatoid Arthritis 2 | 1,171
chronic kidney disease 2 | 90
group 4 medulloblastoma 2 | 1,875
hepatocellular carcinoma 2 | 550
mosaic variegated aneuploidy syndrome 1 2 | 4
sarcoidosis 2 | 368
tuberculosis and treatment for 6 months 2 | 686
Bladder Neoplasm 1 | 109
Cockayne syndrome 1 | 54
Degenerative polyarthritis 1 | 93
Exophthalmos 1 | 16
Liver carcinoma 1 | 217
Liver neoplasms 1 | 109
Microcephaly 1 | 149
Patau syndrome 1 | 15
Sjogren's syndrome 1 | 23
cystic fibrosis and chronic rhinosinusitis 1 | 213
limb girdle muscular dystrophy 2B 1 | 74
substance-related disorder 1 | 105
systemic lupus erythematosus 1 | 172

Tissue

Blood and immune system 77 | 17,995
Digestive Tract 77 | 18,473
Endocrine System 77 | 18,512
Female tissues 77 | 18,647
Liver and Pancreas 77 | 18,136
Male tissues 77 | 17,969
Nervous System 77 | 18,561
Urinary Tract 77 | 18,444
Cardiovascular System 76 | 17,958
Respiratory system 76 | 17,484
Skin and soft tissues 76 | 18,115

Target Family

Enzyme 50 | 4,146
Non-IDG 22 | 11,969
Kinase 5 | 634

GO Process

anaphase-promoting complex-dep... 77 | 77
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cell division cycle protein 20 homolog CDC20 Tbio Non-IDG -2.58287 383.9 269
Serine/threonine-protein kinase PLK1 PLK1 Tchem Kinase -3.06059 1176.3 707
Mitotic checkpoint protein BUB3 BUB3 Tbio Non-IDG -1.91281 73.2 222
Polyubiquitin-C UBC Tbio Non-IDG -2.87696 56.7 130
Polyubiquitin-B UBB Tbio Non-IDG -1.96206 92.3 370
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.86105 71.4 158
26S protease regulatory subunit 6A PSMC3 Tbio Enzyme -1.26468 18.5 271
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.44048 25.4 280
Securin PTTG1 Tbio Non-IDG -2.39265 244.3 267
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.59489 39.3 30