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Development Level

Tbio 64 | 11,651
Tchem 7 | 1,388
Tclin 5 | 612
Tdark 5 | 6,593

IMPC Phenotype

preweaning lethality, complete... 13 | 979
embryonic lethality prior to t... 6 | 278
abnormal embryo size 5 | 220
embryonic lethality prior to o... 5 | 239
embryonic growth retardation 4 | 106
abnormal heart morphology 2 | 162
abnormal placenta size 2 | 20
anophthalmia 2 | 33
impaired glucose tolerance 2 | 75
increased mean corpuscular vol... 2 | 92
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal forebrain morphology 1 | 10
abnormal head shape 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta morphology 1 | 5
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
brachydactyly 1 | 19
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
female infertility 1 | 60
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating glucose ... 1 | 24
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
microphthalmia 1 | 26
pallor 1 | 34
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
sclerocornea 1 | 2
small kidney 1 | 16
small spleen 1 | 19
small testis 1 | 58
syndactyly 1 | 23
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 57 | 8,520
lung cancer 39 | 4,740
psoriasis 39 | 6,694
Carcinoma 33 | 11,493
glioblastoma 33 | 5,792
osteosarcoma 32 | 7,950
Multiple myeloma 29 | 1,332
medulloblastoma, large-cell 24 | 6,241
Breast cancer 23 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
Cancer 21 | 2,499
atypical teratoid / rhabdoid tumor 21 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
non-small cell lung cancer 19 | 2,890
invasive ductal carcinoma 18 | 2,951
group 3 medulloblastoma 17 | 4,104
malignant mesothelioma 16 | 3,232
HIV Infections 15 | 102
ependymoma 15 | 4,679
lung adenocarcinoma 15 | 2,716
adrenocortical carcinoma 14 | 1,428
Waldenstrons macroglobulinemia 13 | 765
adult high grade glioma 13 | 3,801
primitive neuroectodermal tumor 13 | 3,035
dermatomyositis 12 | 966
pancreatic cancer 12 | 2,398
breast carcinoma 11 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Atopic dermatitis 9 | 952
Endometriosis 9 | 540
colon cancer 9 | 1,478
ductal carcinoma in situ 9 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
astrocytoma 8 | 1,146
non primary Sjogren syndrome sicca 8 | 891
oligodendroglioma 8 | 2,850
primary Sjogren syndrome 8 | 735
Pick disease 7 | 1,894
astrocytic glioma 7 | 2,597
diabetes mellitus 7 | 1,728
nasopharyngeal carcinoma 7 | 1,058
subependymal giant cell astrocytoma 7 | 2,287
Astrocytoma, Pilocytic 6 | 3,081
esophageal adenocarcinoma 6 | 737
interstitial cystitis 6 | 2,312
lung carcinoma 6 | 2,843
tuberculosis 6 | 2,010
Intellectual disability 5 | 1,016
Kidney cancer 5 | 2,613
Liver Cirrhosis, Experimental 5 | 769
Mantle cell lymphoma 5 | 23
active Crohn's disease 5 | 922
acute quadriplegic myopathy 5 | 1,158
pituitary cancer 5 | 1,972
posterior fossa group A ependymoma 5 | 468
ulcerative colitis 5 | 1,819
Esophageal Squamous Cell Carcinoma 4 | 77
Osteoporosis 4 | 363
Squamous cell carcinoma of esophagus 4 | 77
acute myeloid leukemia 4 | 783
cutaneous lupus erythematosus 4 | 1,057
group 4 medulloblastoma 4 | 1,855
juvenile dermatomyositis 4 | 1,187
pediatric high grade glioma 4 | 1,064
Acquired metabolic disease 3 | 336
Anemia 3 | 365
Hypoplastic mandible condyle 3 | 275
Mammary Neoplasms, Experimental 3 | 154
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Parkinson's disease 3 | 392
Polycystic ovary syndrome 3 | 360
medulloblastoma 3 | 720
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676
Alzheimer's disease 2 | 658
Animal Mammary Neoplasms 2 | 136
Breast Neoplasms 2 | 445
Clouding of corneal stroma 2 | 50
Colorectal Neoplasms 2 | 243
Congenital Epicanthus 2 | 177
Congestive heart failure 2 | 113
Corneal Opacity 2 | 53
Duchenne muscular dystrophy 2 | 601
Glaucoma 2 | 239
Leukemia 2 | 104
Mammary Neoplasms 2 | 425
Mammary Neoplasms, Animal 2 | 136
Melanoma 2 | 711
Muscle biopsy shows dystrophic changes 2 | 39
Muscular dystrophy 2 | 75
Polyhydramnios 2 | 108
Profound Mental Retardation 2 | 31
Profound intellectual disabilities 2 | 31
Stomach Neoplasms 2 | 300
Triangular face 2 | 58
gastric carcinoma 2 | 807
hepatocellular carcinoma 2 | 547
sarcoidosis 2 | 370
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Endocrine System 81 | 18,159
Blood and immune system 80 | 16,909
Digestive Tract 80 | 17,369
Female tissues 80 | 17,400
Male tissues 80 | 17,142
Nervous System 80 | 16,725
Respiratory system 80 | 16,393
Urinary Tract 80 | 16,678
Cardiovascular System 79 | 15,192
Liver and Pancreas 79 | 16,750
Skin and soft tissues 79 | 17,230

Target Family

Enzyme 50 | 4,145
Non-IDG 26 | 12,091
Kinase 5 | 634

GO Process

anaphase-promoting complex-dep... 81 | 81
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Securin PTTG1 Tbio Non-IDG -2.42127 261.4 311
26S proteasome regulatory subunit 6A PSMC3 Tbio Enzyme -1.29086 19.3 302
Anaphase-promoting complex subunit 5 ANAPC5 Tbio Enzyme -1.45912 28.7 251
26S proteasome non-ATPase regulatory subunit 13 PSMD13 Tbio Enzyme -1.09295 11.9 110
26S proteasome non-ATPase regulatory subunit 3 PSMD3 Tbio Enzyme -1.22269 15.9 168
Mitotic checkpoint protein BUB3 BUB3 Tbio Non-IDG -1.93368 76.1 256
Fizzy-related protein homolog FZR1 Tbio Non-IDG -1.78590 63.2 228
Proteasome activator complex subunit 3 PSME3 Tbio Non-IDG -1.87037 83.7 245
Cullin-3 CUL3 Tbio Non-IDG -3.26322 1670.8 307
Serine/threonine-protein kinase PLK1 PLK1 Tchem Kinase -3.09610 1271.1 856