Development Level

Tbio 25 | 11,445
Tchem 8 | 1,598

IMPC Phenotype

abnormal epididymis morphology 2 | 42
enlarged epididymis 2 | 31
abnormal femur morphology 1 | 14
abnormal kidney morphology 1 | 65
abnormal optic disc morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal urinary bladder morph... 1 | 11
abnormal vitreous body morphol... 1 | 10
cystolithiasis 1 | 3
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased total body fat amoun... 1 | 207
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased circulating glucose ... 1 | 24
increased lean body mass 1 | 172
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499
small kidney 1 | 16

Disease

Carcinoma 24 | 11,493
osteosarcoma 18 | 7,950
ovarian cancer 14 | 8,520
medulloblastoma, large-cell 13 | 6,241
atypical teratoid / rhabdoid tumor 12 | 5,112
ependymoma 12 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung cancer 11 | 4,740
pancreatic cancer 11 | 2,398
psoriasis 11 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
glioblastoma 9 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung carcinoma 9 | 2,843
malignant mesothelioma 9 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
tuberculosis 9 | 2,010
Breast cancer 8 | 3,578
Cystinuria 8 | 18
Lysinuric protein intolerance 8 | 15
group 3 medulloblastoma 8 | 4,104
interstitial cystitis 8 | 2,312
invasive ductal carcinoma 8 | 2,951
active ulcerative colitis 7 | 764
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
Astrocytoma, Pilocytic 6 | 3,081
Cancer 6 | 2,499
Hartnup disease 6 | 13
active Crohn's disease 6 | 922
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
ulcerative colitis 6 | 1,819
Autosomal recessive predisposition 5 | 1,442
Schizophrenia 5 | 1,160
atypical teratoid/rhabdoid tumor 5 | 357
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,855
Epilepsy 4 | 792
Iminoglycinuria 4 | 4
Muscle hypotonia 4 | 571
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
lung adenocarcinoma 4 | 2,716
pediatric high grade glioma 4 | 1,064
Allan-Herndon-Dudley syndrome 3 | 11
Atopic dermatitis 3 | 952
Barrett's esophagus 3 | 182
Cognitive delay 3 | 608
Duchenne muscular dystrophy 3 | 601
Dull intelligence 3 | 645
Endometriosis 3 | 540
Failure to gain weight 3 | 365
Global developmental delay 3 | 608
HYPERGLYCINURIA (disorder) 3 | 12
Hyperglycinuria 3 | 3
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Multiple myeloma 3 | 1,332
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
nephrosclerosis 3 | 333
spina bifida 3 | 1,074
Amyotrophic lateral sclerosis 2 | 451
Cerebral atrophy 2 | 178
Congenital Epicanthus 2 | 177
Hepatomegaly 2 | 285
Highly variable severity 2 | 157
Kidney Failure 2 | 111
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Nephrolithiasis 2 | 56
Pellagra 2 | 26
Polycystic ovary syndrome 2 | 360
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Seizures 2 | 596
Variable expressivity 2 | 157
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cutaneous lupus erythematosus 2 | 1,057
gastric cancer 2 | 459
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Urinary Tract 33 | 16,678
Blood and immune system 32 | 16,909
Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Male tissues 32 | 17,142
Nervous System 32 | 16,725
Skin and soft tissues 32 | 17,230
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Respiratory system 30 | 16,393
Cardiovascular System 26 | 15,192

Target Family

Transporter 32 | 473
Non-IDG 1 | 12,091

GO Process

amino acid transport 33 | 33
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cationic amino acid transporter 3 SLC7A3 Tbio Transporter -2.20835 146.6 38
Proton-coupled amino acid transporter 2 SLC36A2 Tchem Transporter -1.78507 61.5 88
Sodium-coupled neutral amino acid transporter 5 SLC38A5 Tbio Transporter -3.03889 1061.8 77
Sodium-coupled neutral amino acid transporter 3 SLC38A3 Tbio Transporter 0.00000 59
Cationic amino acid transporter 2 SLC7A2 Tbio Transporter -1.55868 37.6 57
Sodium-coupled neutral amino acid transporter 2 SLC38A2 Tbio Transporter -1.98482 96.5 91
Sodium-dependent neutral amino acid transporter B(0)AT1 SLC6A19 Tchem Transporter -1.89653 74.4 32
Sodium- and chloride-dependent betaine transporter SLC6A12 Tchem Transporter -2.34582 212.0 104
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 Tchem Transporter -1.42715 25.8 76
Y+L amino acid transporter 2 SLC7A6 Tbio Transporter -1.48428 28.6 64