Development Level

Tbio 4 | 11,445
Tclin 2 | 613

IMPC Phenotype

decreased bone mineral density 2 | 126
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
preweaning lethality, incomple... 1 | 499

Disease

Alcoholic Intoxication, Chronic 4 | 289
Carcinoma 4 | 11,493
Alcohol dependence 3 | 107
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
psoriasis 3 | 6,694
Alcohol abuse 2 | 50
Alcoholic neuropathy 2 | 3
Liver Cirrhosis, Experimental 2 | 769
Liver disease 2 | 237
ductal carcinoma in situ 2 | 1,745
esophageal cancer 2 | 22
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
nasopharyngeal carcinoma 2 | 1,058
ovarian cancer 2 | 8,520
ALCOHOL SENSITIVITY, ACUTE 1 | 1
Accidental poisoning by methyl alcohol 1 | 3
Alcohol-Induced Disorders 1 | 1
Alcohol-Related Disorders 1 | 5
Alcoholic Intoxication 1 | 34
Alcoholism 1 | 45
Asthma 1 | 385
Bipolar Disorder 1 | 666
Brain infarction 1 | 22
Cancer 1 | 2,499
Colorectal Neoplasms 1 | 243
Complications of Diabetes Mellitus 1 | 5
Coronary artery disease 1 | 268
Delayed oxidation of acetaldehyde 1 | 1
Dermatitis, Occupational 1 | 4
Diabetes Complications 1 | 6
Enterocolitis, Necrotizing 1 | 17
Esophageal Neoplasms 1 | 69
Esophageal Squamous Cell Carcinoma 1 | 77
Ethylene Glycol Toxicity 1 | 3
Facial flushing after alcohol intake 1 | 1
Flushing 1 | 60
Genetic Predisposition to Disease 1 | 27
Hangover from alcohol 1 | 2
Heart Injuries 1 | 3
Heroin dependence 1 | 30
Infertility, Male 1 | 46
Intracranial aneurysm 1 | 24
Kidney disease 1 | 430
Male infertility 1 | 206
Necrotizing Enterocolitis 1 | 17
Pancreatitis 1 | 123
Paranoid Schizophrenia 1 | 18
Precancerous Conditions 1 | 80
Retinitis pigmentosa 23 1 | 27
Schizophrenia 1 | 1,160
Squamous cell carcinoma of esophagus 1 | 77
Substance abuse 1 | 59
Succinic semialdehyde dehydrogenase deficiency 1 | 16
Vascular Diseases 1 | 16
Ventricular Dysfunction 1 | 7
Wernicke-Korsakoff syndrome 1 | 10
adrenocortical carcinoma 1 | 1,428
alcohol use disorder 1 | 12
atypical teratoid / rhabdoid tumor 1 | 5,112
breast carcinoma 1 | 1,638
chronic lymphosyte leukemia 1 | 204
chronic rhinosinusitis 1 | 512
cystic fibrosis 1 | 1,696
esophageal adenocarcinoma 1 | 737
fibroadenoma 1 | 559
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
limb girdle muscular dystrophy 2B 1 | 40
lung carcinoma 1 | 2,843
medulloblastoma, large-cell 1 | 6,241
non-small cell lung carcinoma 1 | 317
osteosarcoma 1 | 7,950
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
primitive neuroectodermal tumor 1 | 3,035
subependymal giant cell astrocytoma 1 | 2,287
substance-related disorder 1 | 162
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192
Nervous System 5 | 16,725

Target Family

Enzyme 6 | 4,145

GO Process

alcohol metabolic process 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dehydrogenase/reductase SDR family member 4 DHRS4 Tbio Enzyme -1.65486 46.6 122
Alcohol dehydrogenase 4 ADH4 Tbio Enzyme -2.30746 247.9 210
Aldehyde dehydrogenase family 3 member B2 ALDH3B2 Tbio Enzyme -0.92036 7.80 176
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470
Aldehyde dehydrogenase family 3 member B1 ALDH3B1 Tbio Enzyme 0.00000 182
Alcohol dehydrogenase 1A ADH1A Tclin Enzyme -2.41845 265.1 167